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GENE：PPFIA3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPFIA3
FullNmae PTPRF interacting protein alpha 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9247
EnsembleID ENSG00000177380
Uniprot O75145

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPFIA3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPFIA3 GO:0001669,GO:0005515,GO:0005829,GO:0007269,GO:0016081,GO:0048172,GO:0048786,GO:0048786,GO:0050808,GO:0098831,GO:0098875,GO:0098978

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 PPFIA3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PPFIA3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPFIA3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000004BACE PPFIA3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D PPFIA3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB PPFIA3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C PPFIA3 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPM1A PPFIA3 25361965 interaction type N/A PTMCode2
PPFIA3 PPM1A 25361965 interaction type N/A PTMCode2
PPFIA3 PPP2CA 25361965 interaction type N/A PTMCode2
PPP2CA PPFIA3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1R13B PPFIA3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SORBS3 PPFIA3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP2R1A PPFIA3 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PPFIA1 PPFIA3 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PIK3R1 PPFIA3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GIT1 PPFIA3 12923177 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PTPRF PPFIA3 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPRS PPFIA3 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PPFIBP1 PPFIA3 25348397 N/A physical interaction,in vitro ComPPI
PPP2CB PPFIA3 25348397 N/A physical interaction ComPPI
PPP2CA PPFIA3 18782753 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
RAB3IL1 PPFIA3 25348397 N/A physical interaction ComPPI
PPFIA2 PPFIA3 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PPFIA3 PTPRU 14525934 25348397 9624153 N/A experimental interaction detection,in vitro ComPPI,HPRD
PPFIA3 PPFIBP2 14525934 25348397 9624153 N/A experimental interaction detection,in vitro ComPPI,HPRD
PPFIA3 ERC2 12923177 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PPFIA3 CAST 12923177 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PPFIA3 GPS2 25348397 N/A physical interaction ComPPI
PPFIA3 PTPRD 14525934 25348397 9624153 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PPFIA3 EMILIN1 25348397 N/A physical interaction ComPPI
PPFIA3 TRIM25 25348397 N/A physical interaction ComPPI
PPFIA3 LNX1 25348397 N/A physical interaction ComPPI
PPFIA3 TFIP11 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPFIA3 PPFIA3 14525934 9624153 N/A experimental interaction detection HPRD
S100A10 PPFIA3 24234451 30021884 physical association cross-linking study IntAct

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