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GENE：PSMA7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMA7
FullNmae proteasome 20S subunit alpha 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9536
EnsembleID ENSG00000101182
Uniprot O14818

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMA7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMA7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMA7 apoptosis 38173490 PSMA7 overexpression significantly promoted the proliferation, migration and invasion of Eca109 and KYSE150 cells, and significantly promoted apoptosis. retulator signature

Go Annotation:

GeneSymbol Go id
PSMA7 GO:0000502,GO:0000502,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0005839,GO:0010498,GO:0019773,GO:0019773,GO:0019773,GO:0042802,GO:0043161,GO:0070062,GO:0098794

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMA7 hsa:5688 path:hsa03050 Proteasome - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05020 Prion disease - Homo sapiens (human)
PSMA7 hsa:5688 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAVS PSMA7 19734229 23180781 physical association anti tag coimmunoprecipitation InnateDB
ISG15 PSMA7 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PSMA7 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMA7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA PSMA7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMA7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PSMA7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PSMA7 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 PSMA7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 PSMA7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002F5FEE PSMA7 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000034B6F5 PSMA7 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 PSMA7 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000184017 PSMA7 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00003E5E03 PSMA7 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ABL1 PSMA7 22135298 phosphorylation N/A PhosphoSite
ABL2 PSMA7 22135298 phosphorylation N/A PhosphoSite
PSMA4 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMA4 25361965 interaction type N/A PTMCode2
PSMA6 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMA6 25361965 interaction type N/A PTMCode2
PSMC4 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMC4 25361965 interaction type N/A PTMCode2
PSMD6 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD6 25361965 interaction type N/A PTMCode2
PSMD8 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD8 25361965 interaction type N/A PTMCode2
PSMD1 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD1 25361965 interaction type N/A PTMCode2
PSMC1 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMC1 25361965 interaction type N/A PTMCode2
PSMB6 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB6 25361965 interaction type N/A PTMCode2
PSMB1 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB1 25361965 interaction type N/A PTMCode2
PSMA5 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMA5 25361965 interaction type N/A PTMCode2
PSMA1 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMA1 25361965 interaction type N/A PTMCode2
PSMB3 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB3 25361965 interaction type N/A PTMCode2
HIF1A PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 HIF1A 25361965 interaction type N/A PTMCode2
PSMB10 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB10 25361965 interaction type N/A PTMCode2
PSMD11 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD11 25361965 interaction type N/A PTMCode2
PSMA7 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD14 25361965 interaction type N/A PTMCode2
PSMD14 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB9 25361965 interaction type N/A PTMCode2
PSMB9 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 PSMA7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB7 25361965 interaction type N/A PTMCode2
PSMB4 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB4 25361965 interaction type N/A PTMCode2
PSMD7 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMD7 25361965 interaction type N/A PTMCode2
PSMA3 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMA3 25361965 interaction type N/A PTMCode2
RAB7A PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 RAB7A 25361965 interaction type N/A PTMCode2
PIPSL PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PIPSL 25361965 interaction type N/A PTMCode2
CUL1 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 CUL1 25361965 interaction type N/A PTMCode2
PSMC3 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF1B PSMA7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAG3 PSMA7 25348397 N/A physical interaction ComPPI
ISG15 PSMA7 25348397 N/A physical interaction ComPPI
SNRPA1 PSMA7 25348397 N/A physical interaction ComPPI
RBM3 PSMA7 25348397 N/A physical interaction ComPPI
PSMC3 PSMA7 25348397 N/A physical interaction ComPPI
PSMC6 PSMA7 25348397 N/A physical interaction ComPPI
PSMD14 PSMA7 25348397 N/A physical interaction ComPPI
PSMD7 PSMA7 25348397 N/A physical interaction ComPPI
VCP PSMA7 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GABARAPL2 PSMA7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SKP1 PSMA7 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
MCM2 PSMA7 25348397 N/A physical interaction ComPPI
PSMB2 PSMA7 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
INSIG2 PSMA7 25348397 N/A physical interaction ComPPI
AP3M1 PSMA7 25348397 N/A physical interaction ComPPI
ERRFI1 PSMA7 25348397 N/A physical interaction ComPPI
ABRAXAS2 PSMA7 19214193 24234451 25348397 association biochemical ComPPI,IntAct
JUN PSMA7 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 PSMA7 25348397 N/A physical interaction ComPPI
HIF1A PSMA7 11389899 14525934 18313384 24234451 25348397 27898060 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
COPS5 PSMA7 25348397 N/A physical interaction ComPPI
PSMA3 PSMA7 14525934 15225636 17948026 21900206 21988832 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PSMD11 PSMA7 25348397 N/A physical interaction ComPPI
CUL3 PSMA7 25348397 N/A physical interaction ComPPI
RAB7A PSMA7 25348397 N/A physical interaction ComPPI
UBC PSMA7 25348397 N/A physical interaction ComPPI
NTRK1 PSMA7 25348397 N/A physical interaction ComPPI
P4HB PSMA7 25348397 N/A physical interaction ComPPI
PLK1 PSMA7 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PSMA1 PSMA7 12376572 14525934 14733938 15225636 17948026 24234451 25348397 25599644 29568061 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,two hybrid,cosedimentation in solution,experimental interaction detection,pull down,x-ray crystallography,physical interaction,in vitro,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
PSMA6 PSMA7 14525934 14733938 15225636 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PSMA5 PSMA7 14525934 15225636 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PSMB9 PSMA7 25348397 N/A physical interaction ComPPI
MYC PSMA7 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RMND5B PSMA7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CFTR PSMA7 25348397 N/A physical interaction ComPPI
MAPK6 PSMA7 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD8 PSMA7 25348397 N/A physical interaction ComPPI
PSMB8 PSMA7 25348397 N/A physical interaction ComPPI
PSMD1 PSMA7 25348397 N/A physical interaction ComPPI
SYVN1 PSMA7 25348397 N/A physical interaction ComPPI
PSMC5 PSMA7 25348397 N/A physical interaction ComPPI
HUWE1 PSMA7 25348397 N/A physical interaction ComPPI
RAD23A PSMA7 25348397 N/A physical interaction ComPPI
SRPK1 PSMA7 23602568 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
NEDD8 PSMA7 25348397 N/A physical interaction ComPPI
MDM2 PSMA7 25348397 N/A physical interaction ComPPI
SPTBN1 PSMA7 25348397 N/A physical interaction ComPPI
CUL1 PSMA7 25348397 N/A physical interaction ComPPI
EGFR PSMA7 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
PSMC4 PSMA7 25348397 N/A physical interaction ComPPI
TIMP2 PSMA7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NOS2 PSMA7 25348397 N/A physical interaction ComPPI
RIPK2 PSMA7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD2 PSMA7 25348397 N/A physical interaction ComPPI
VCAM1 PSMA7 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 PSMA7 25348397 N/A physical interaction ComPPI
PRKN PSMA7 14525934 15987638 25348397 N/A anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
PSMD4 PSMA7 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP8 PSMA7 25348397 N/A physical interaction ComPPI
BARD1 PSMA7 25348397 N/A physical interaction ComPPI
SEM1 PSMA7 25348397 N/A physical interaction ComPPI
PSMB5 PSMA7 25348397 N/A physical interaction ComPPI
INSIG1 PSMA7 25348397 N/A physical interaction ComPPI
PSME3 PSMA7 25348397 N/A physical interaction ComPPI
NOD1 PSMA7 25348397 N/A physical interaction ComPPI
PSME1 PSMA7 25348397 N/A physical interaction ComPPI
UBQLN1 PSMA7 25348397 N/A physical interaction ComPPI
TERF1 PSMA7 25348397 N/A physical interaction ComPPI
PSMC1 PSMA7 11361004 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
AMFR PSMA7 25348397 N/A physical interaction ComPPI
PPP3R1 PSMA7 21256111 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BRCA1 PSMA7 25348397 N/A physical interaction ComPPI
PSMB4 PSMA7 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HECW2 PSMA7 25348397 N/A physical interaction ComPPI
PSMB1 PSMA7 25348397 N/A physical interaction ComPPI
PSMB3 PSMA7 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PSMB7 PSMA7 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PSMA7 PSMA2 14525934 15225636 17948026 21900206 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PSMA7 PSMA4 14525934 14733938 15225636 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
PSMA7 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 PSMD13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 RNF185 25348397 N/A physical interaction ComPPI
PSMA7 PSMD6 25348397 N/A physical interaction ComPPI
PSMA7 SEM1 25348397 N/A physical interaction ComPPI
PSMA7 MAVS 25348397 N/A physical interaction ComPPI
PSMA7 AIMP1 25348397 N/A physical interaction ComPPI
PSMA7 TBXA2R 25348397 N/A physical interaction ComPPI
PSMA7 ABL1 25348397 N/A physical interaction ComPPI
PSMA7 ABL2 25348397 N/A physical interaction ComPPI
PSMA7 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 POMP 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PSMA7 ECSCR 19416853 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PSMA7 APP 25348397 N/A physical interaction ComPPI
PSMA7 PSMB6 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 PSMC2 25348397 N/A physical interaction ComPPI
PSMA7 PSMD3 25348397 N/A physical interaction ComPPI
PSMA7 PSMD12 25348397 N/A physical interaction ComPPI
PSMA7 PSMD5 25348397 N/A physical interaction ComPPI
PSMA7 PSMA8 25348397 N/A physical interaction ComPPI
PSMA7 SAMD1 25348397 N/A physical interaction ComPPI
PSMA7 MRPS16 25348397 N/A physical interaction ComPPI
PSMA7 FN1 25348397 N/A physical interaction ComPPI
PSMA7 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 CAPN10 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMA7 PSME4 25348397 N/A physical interaction ComPPI
PSMA7 PYCR3 25348397 N/A physical interaction ComPPI
PSMA7 PSMG3 25348397 N/A physical interaction ComPPI
PSMA7 PSMG1 25348397 N/A physical interaction ComPPI
PSMA7 AMBRA1 25348397 N/A physical interaction ComPPI
PSMA7 EXOSC9 25348397 N/A physical interaction ComPPI
PSMA7 CEP85 25348397 N/A physical interaction ComPPI
PSMA7 TSC22D2 25348397 N/A physical interaction ComPPI
PSMA7 CYLD 25348397 N/A physical interaction ComPPI
PSMA7 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA7 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA7 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA7 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA7 ACTR6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA7 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA7 XBP1 25348397 N/A pull down ComPPI
PSMA7 L3MBTL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMA7 L3MBTL4 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMA7 YOD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ADRM1 PSMA7 25348397 N/A physical interaction ComPPI
PSMF1 PSMA7 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK4 PSMA7 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMA7 PSMA7 14525934 15225636 17948026 24234451 physical association two hybrid,experimental interaction detection,pull down,two hybrid HPRD,IntAct
OXTR PSMA7 24234451 28298427 physical association ubiquitin reconstruction IntAct
ABL2 PSMA7 16678104 25620702 27898060 inhibition N/A OmniPath
PSMA7 MAVS 19734229 27898060 N/A N/A OmniPath
ABL1 PSMA7 16678104 20841568 25620702 27898060 inhibition N/A OmniPath
ISG15 PSMA7 16009940 27898060 N/A N/A OmniPath

Visualization










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