Gene Information gene info

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GENE：RUFY1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RUFY1
FullNmae RUN and FYVE domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19760
EnsembleID ENSG00000176783
Uniprot Q96T51

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RUFY1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RUFY1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RUFY1 GO:0005515,GO:0005737,GO:0005768,GO:0005829,GO:0005829,GO:0006897,GO:0007264,GO:0008289,GO:0015031,GO:0016607,GO:0017124,GO:0030100,GO:0030100,GO:0031901,GO:0042169,GO:0043231,GO:0043231,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RUFY1 hsa:80230 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PIAS2 RUFY1 21988832 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 RUFY1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 RUFY1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RUFY1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RUFY1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
BMX RUFY1 22135298 phosphorylation N/A PhosphoSite
EPHA3 RUFY1 25361965 interaction type N/A PTMCode2
RUFY1 EPHA3 25361965 interaction type N/A PTMCode2
RAB4A RUFY1 25361965 interaction type N/A PTMCode2
RUFY1 RAB4A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIAS2 RUFY1 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
RAB39B RUFY1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UTP25 RUFY1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RALBP1 RUFY1 25348397 N/A physical interaction ComPPI
RAB4A RUFY1 11172003 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RAB14 RUFY1 25348397 N/A physical interaction ComPPI
HSPBP1 RUFY1 25348397 N/A physical interaction ComPPI
TUBB RUFY1 25348397 N/A physical interaction ComPPI
TXNDC17 RUFY1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ASPA RUFY1 25348397 N/A physical interaction ComPPI
AP3M1 RUFY1 25348397 N/A physical interaction ComPPI
FOSL2 RUFY1 25348397 N/A physical interaction ComPPI
PKN2 RUFY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 RUFY1 25348397 N/A physical interaction ComPPI
COPB2 RUFY1 25348397 N/A physical interaction ComPPI
RAB3IP RUFY1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RABEP1 RUFY1 25348397 N/A physical interaction ComPPI
RUFY1 EPHA3 11877430 14525934 24234451 25348397 association two hybrid,coimmunoprecipitation,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,IntAct
RUFY1 ITSN2 25348397 N/A physical interaction ComPPI
RUFY1 RAB5A 25348397 N/A physical interaction ComPPI
RUFY1 CCT8 25348397 N/A physical interaction ComPPI
RUFY1 VPS26A 25348397 N/A physical interaction ComPPI
RUFY1 HCK 17868192 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
RUFY1 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RUFY1 KLC4 25348397 N/A physical interaction ComPPI
RUFY1 PSME4 25348397 N/A physical interaction ComPPI
RUFY1 COPG1 25348397 N/A physical interaction ComPPI
RUFY1 COPZ1 25348397 N/A physical interaction ComPPI
RUFY1 SART3 25348397 N/A physical interaction ComPPI
RUFY1 TELO2 25348397 N/A physical interaction ComPPI
RUFY1 TTI1 25348397 N/A physical interaction ComPPI
RUFY1 AP3B2 25348397 N/A physical interaction ComPPI
RUFY1 DYNC1H1 25348397 N/A physical interaction ComPPI
RUFY1 TUBA1A 25348397 N/A physical interaction ComPPI
RUFY1 AP3D1 25348397 N/A physical interaction ComPPI
RUFY1 AP3S1 25348397 N/A physical interaction ComPPI
RUFY1 CCDC183 25348397 N/A physical interaction ComPPI
RUFY1 FAS 25348397 N/A physical interaction ComPPI
RUFY1 ST8SIA1 25348397 N/A physical interaction ComPPI
RUFY1 WDFY2 25348397 N/A physical interaction ComPPI
RUFY1 TGOLN2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RUFY1 SRA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RUFY1 RUFY2 25348397 N/A physical interaction ComPPI
RUFY1 NLN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RUFY1 PMF1 25348397 N/A physical interaction ComPPI
RUFY1 RUFY3 25348397 N/A physical interaction ComPPI
RUFY1 SYNC 25348397 N/A physical interaction ComPPI
RUFY1 SNX8 25348397 N/A physical interaction ComPPI
RUFY1 RUBCNL 25348397 N/A physical interaction ComPPI
RUFY1 CD79B 25348397 N/A physical interaction ComPPI
RUFY1 ST8SIA4 25348397 N/A physical interaction ComPPI
RUFY1 CERT1 25348397 N/A physical interaction ComPPI
RUFY1 VSIG1 25348397 N/A physical interaction ComPPI
RUFY1 CD70 25348397 N/A physical interaction ComPPI
RUFY1 TIMM23 25348397 N/A physical interaction ComPPI
RUFY1 EEA1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RUFY1 RAB9A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BMX RUFY1 11877430 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
RUFY1 RUFY1 24234451 25416956 physical association two hybrid array IntAct
PIAS2 RUFY1 21988832 27898060 N/A N/A OmniPath
BMX RUFY1 11877430 27898060 N/A N/A OmniPath

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