GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
RUFY3 |
| FullNmae |
RUN and FYVE domain containing 3 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:30285 |
| EnsembleID |
ENSG00000018189 |
| Uniprot |
Q7L099 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| RUFY3 |
pyroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
| RUFY3 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| RUFY3 |
GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0007015,GO:0007399,GO:0012505,GO:0016020,GO:0030027,GO:0030154,GO:0030175,GO:0030335,GO:0030424,GO:0030424,GO:0030425,GO:0030425,GO:0030426,GO:0043025,GO:0043204,GO:0045773,GO:0050770,GO:0050771,GO:0070161,GO:0090316,GO:2000114 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| AR |
RUFY3 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| ETS1 |
RUFY3 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
RUFY3 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| FOXP3 |
RUFY3 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| SMARCA4 |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| SPI1 |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TAL1 |
RUFY3 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00000F31F4 |
RUFY3 |
19074876
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS00000B59A2 |
RUFY3 |
19074876
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS000009262D |
RUFY3 |
18591254
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS000017EA6A |
RUFY3 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| UNC119 |
RUFY3 |
14525934
16169070
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid |
ComPPI,HPRD,IntAct |
| NTRK1 |
RUFY3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RUFY1 |
RUFY3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RUFY2 |
RUFY3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ABI3 |
RUFY3 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| RAB9A |
RUFY3 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
| GANAB |
RUFY3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RUFY3 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
| CTTNBP2NL |
RUFY3 |
24234451
24255178
25348397
|
colocalization |
physical interaction,proximity-dependent biotin identification |
ComPPI,IntAct |
| SMARCA2 |
RUFY3 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization