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GENE：SERPINE2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERPINE2
FullNmae serpin family E member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8951
EnsembleID ENSG00000135919
Uniprot P07093

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERPINE2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SERPINE2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SERPINE2 GO:0004867,GO:0004867,GO:0004867,GO:0005102,GO:0005515,GO:0005539,GO:0005576,GO:0005576,GO:0005615,GO:0005829,GO:0008201,GO:0008285,GO:0010757,GO:0010757,GO:0010766,GO:0010951,GO:0010955,GO:0021683,GO:0030154,GO:0030163,GO:0030168,GO:0030195,GO:0030195,GO:0030308,GO:0030334,GO:0031091,GO:0031091,GO:0031594,GO:0032940,GO:0033363,GO:0042177,GO:0042628,GO:0045861,GO:0045879,GO:0048505,GO:0048711,GO:0050974,GO:0051966,GO:0060291,GO:0060384,GO:0061108,GO:0062023,GO:0062023,GO:0090331,GO:1903561

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERPINE2 hsa:5270 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SERPINE2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SERPINE2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA3 SERPINE2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SERPINE2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SERPINE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SERPINE2 N/A trascriptional regulation,stimulation inferred by curator TFlink
USF1 SERPINE2 N/A trascriptional regulation,stimulation inferred by curator TFlink
USF2 SERPINE2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 SERPINE2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001DE669 SERPINE2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
F2 SERPINE2 25361965 interaction type N/A PTMCode2
SERPINE2 F2 25361965 interaction type N/A PTMCode2
COL4A5 SERPINE2 25361965 interaction type N/A PTMCode2
SERPINE2 COL4A5 25361965 interaction type N/A PTMCode2
COL4A2 SERPINE2 25361965 interaction type N/A PTMCode2
SERPINE2 COL4A2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KEAP1 SERPINE2 25348397 N/A physical interaction ComPPI
COL4A5 SERPINE2 14525934 25348397 8006028 N/A experimental interaction detection,in vivo ComPPI,HPRD
COL4A6 SERPINE2 14525934 25348397 8006028 N/A experimental interaction detection,in vivo ComPPI,HPRD
BCAT1 SERPINE2 25348397 N/A physical interaction ComPPI
F2 SERPINE2 12106474 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PLAT SERPINE2 25348397 N/A physical interaction ComPPI
APOD SERPINE2 25348397 N/A physical interaction ComPPI
COL4A2 SERPINE2 14525934 25348397 8006028 N/A experimental interaction detection,in vivo ComPPI,HPRD
XPO5 SERPINE2 25348397 N/A physical interaction ComPPI
SERPINE2 COL4A3 14525934 25348397 8006028 N/A experimental interaction detection,in vivo ComPPI,HPRD
SERPINE2 COL4A1 25348397 N/A in vivo ComPPI
SERPINE2 COL4A4 14525934 25348397 8006028 N/A experimental interaction detection,in vivo ComPPI,HPRD
SERPINE2 PLAU 25348397 26186194 27898060 9184208 N/A physical interaction ComPPI,OmniPath
SERPINE2 ELAVL1 25348397 N/A physical interaction ComPPI
SERPINE2 AGL 25348397 N/A physical interaction ComPPI
SERPINE2 NCBP1 25348397 N/A physical interaction ComPPI
SERPINE2 DUS3L 25348397 N/A physical interaction ComPPI
SERPINE2 HNRNPUL1 25348397 N/A physical interaction ComPPI
SERPINE2 SP100 25348397 N/A physical interaction ComPPI
SERPINE2 FAM9B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SERPINE2 KLK2 25348397 N/A physical interaction ComPPI
SERPINE2 KLK13 25348397 N/A physical interaction ComPPI
SERPINE2 RTN1 25348397 N/A physical interaction ComPPI
SERPINE2 SCGB2A2 25348397 N/A physical interaction ComPPI
SERPINE2 PMEL 25348397 N/A physical interaction ComPPI
APEH SERPINE2 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009B6D65 SERPINE2 27087310 direct interaction,inhibition N/A NPInter

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