Gene Information gene info

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GENE：SGCB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SGCB
FullNmae sarcoglycan beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10806
EnsembleID ENSG00000163069
Uniprot Q16585

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SGCB pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SGCB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SGCB autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SGCB GO:0005515,GO:0005737,GO:0005856,GO:0005886,GO:0007517,GO:0009749,GO:0010467,GO:0016010,GO:0016012,GO:0042383,GO:0042593,GO:0044381,GO:0055013,GO:0097084

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SGCB hsa:6443 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
SGCB hsa:6443 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)
SGCB hsa:6443 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)
SGCB hsa:6443 path:hsa05416 Viral myocarditis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 SGCB 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SGCB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SGCB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SGCB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SGCB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SGCB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272039 SGCB 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000F31F4 SGCB 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 SGCB 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D SGCB 18591254 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SGCD SGCB 25361965 interaction type N/A PTMCode2
SGCB SGCD 25361965 interaction type N/A PTMCode2
DMD SGCB 25361965 interaction type N/A PTMCode2
SGCB DMD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TMEM11 SGCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMIM3 SGCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NINJ1 SGCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGCD SGCB 14525934 25348397 9864373 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SGCG SGCB 12189167 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TNF SGCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EHHADH SGCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM63 SGCB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
CHRND SGCB 25348397 N/A physical interaction ComPPI
SGCB SGCA 11747090 14525934 1461282 25348397 27898060 9864373 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SGCB ZACN 25348397 N/A physical interaction ComPPI
SGCB GLRA2 25348397 N/A physical interaction ComPPI
SGCB HTR3A 25348397 N/A physical interaction ComPPI
SGCB TMED6 25348397 N/A physical interaction ComPPI
SGCB TCTN2 25348397 N/A physical interaction ComPPI
SGCB TSPAN17 25348397 N/A physical interaction ComPPI
SGCB MGST2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGCB SLC52A1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGCB MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGCB APOL3 25348397 N/A two hybrid ComPPI
PTTG1IP SGCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGCZ SGCB 12189167 14525934 N/A experimental interaction detection HPRD
HTR2C SGCB 24234451 28298427 physical association ubiquitin reconstruction IntAct
ADRA1A SGCB 24234451 28298427 physical association ubiquitin reconstruction IntAct
LTB4R2 SGCB 24234451 28298427 physical association ubiquitin reconstruction IntAct
DAG1 SGCB 24234451 association cross-linking study IntAct

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