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GENE：SNX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SNX1
FullNmae sorting nexin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11172
EnsembleID ENSG00000028528
Uniprot Q13596

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SNX1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SNX1 GO:0005154,GO:0005158,GO:0005515,GO:0005737,GO:0005764,GO:0005768,GO:0005768,GO:0005794,GO:0005829,GO:0006886,GO:0010008,GO:0010008,GO:0016020,GO:0030027,GO:0030904,GO:0030905,GO:0030905,GO:0031623,GO:0031901,GO:0031982,GO:0032991,GO:0034498,GO:0034498,GO:0035091,GO:0035091,GO:0042147,GO:0042147,GO:0042802,GO:0042803,GO:0043231,GO:0045296,GO:0046982,GO:0072673,GO:1990459,GO:1990460

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SNX1 hsa:6642 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SNX1 CHRM1 15452121 23180781 physical association pull down InnateDB
SNX1 CHRM4 15452121 23180781 physical association pull down InnateDB
CHRM5 SNX1 15452121 23180781 physical association pull down InnateDB
SNX1 TAC1 15452121 23180781 physical association pull down InnateDB
SNX1 TAC3 15452121 23180781 physical association pull down InnateDB
OXTR SNX1 15452121 23180781 physical association pull down InnateDB
SNX1 ADRB2 15452121 23180781 physical association pull down InnateDB
SNX1 AVPR2 15452121 23180781 physical association pull down InnateDB
SNX1 CHRM5 15452121 23180781 physical association pull down InnateDB
SNX1 TACR1 15452121 23180781 physical association pull down InnateDB
SNX1 TACR2 15452121 23180781 physical association pull down InnateDB
SNX1 TACR3 15452121 23180781 physical association pull down InnateDB
SNX1 OXTR 15452121 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR SNX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SNX1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SNX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC SNX1 12695333 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SNX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SNX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SNX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SNX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SNX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SNX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000015F70F SNX1 21427358 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS00000F4AC3 SNX1 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS000015F70F SNX1 21427358 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase
URS00001799A3 SNX1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BD1DE SNX1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B SNX1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SNX1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE SNX1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 SNX1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FAM90A1 SNX1 25348397 N/A physical interaction ComPPI
FXR2 SNX1 25348397 N/A physical interaction ComPPI
SH3GLB1 SNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPX7 SNX1 25348397 N/A physical interaction ComPPI
STAT1 SNX1 25348397 N/A physical interaction ComPPI
TK1 SNX1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LSM2 SNX1 25348397 N/A physical interaction ComPPI
MCM2 SNX1 25348397 N/A physical interaction ComPPI
FUNDC1 SNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
REEP6 SNX1 21988832 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RABAC1 SNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HCLS1 SNX1 25348397 N/A physical interaction ComPPI
JUN SNX1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PDGFRB SNX1 14525934 25348397 9819414 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HGS SNX1 11110793 14525934 19874558 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
DLD SNX1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 SNX1 25348397 N/A physical interaction ComPPI
CDH1 SNX1 25348397 N/A physical interaction ComPPI
SNX1 F2R 12058063 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNX1 LEPR 14525934 25348397 9819414 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SNX1 ACVR1B 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SNX1 ACVR2B 11279102 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SNX1 SNX2 11102511 14525934 24234451 25348397 9819414 physical association experimental interaction detection,physical interaction,in vitro,in vivo,lexa b52 complementation ComPPI,HPRD,IntAct
SNX1 SNX6 11279102 14525934 21988832 23524952 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
SNX1 EGFR 14525934 25348397 8638121 9819414 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
SNX1 INSR 14525934 25348397 9819414 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SNX1 ATXN7 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNX1 UFD1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNX1 DNAJC13 25348397 N/A physical interaction ComPPI
SNX1 APP 25348397 N/A physical interaction ComPPI
SNX1 ARFIP2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNX1 GSPT2 25348397 N/A physical interaction ComPPI
SNX1 MAT2B 25348397 N/A physical interaction ComPPI
SNX1 NASP 25348397 N/A physical interaction ComPPI
SNX1 SHMT2 25348397 N/A physical interaction ComPPI
SNX1 ATG7 25348397 N/A physical interaction ComPPI
SNX1 CTTN 25348397 N/A physical interaction ComPPI
SNX1 GARS1 25348397 N/A physical interaction ComPPI
SNX1 UGDH 25348397 N/A physical interaction ComPPI
SNX1 RTN3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX1 ARL6IP1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX1 AGTRAP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX1 RTN4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX1 CMTM5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX1 SNX32 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNX1 MOV10 25348397 N/A physical interaction ComPPI
SNX1 NXF1 25348397 N/A physical interaction ComPPI
SNX1 BIN3 25348397 N/A physical interaction ComPPI
SNX1 ZNF397 25348397 N/A physical interaction ComPPI
SNX1 TMOD1 25348397 N/A physical interaction ComPPI
SNX1 DNM3 25348397 N/A physical interaction ComPPI
SNX1 GNAT2 25348397 N/A physical interaction ComPPI
SNX1 CCNL2 25348397 N/A physical interaction ComPPI
SNX1 GSPT1 25348397 N/A physical interaction ComPPI
SNX1 RUVBL2 25348397 N/A physical interaction ComPPI
SNX1 SMYD2 25348397 N/A physical interaction ComPPI
SNX1 WDFY1 25348397 N/A physical interaction ComPPI
SNX1 SNX5 23085988 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
SNX1 VPS26A 11102511 24234451 25348397 association,physical association anti bait coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
SNX1 VPS26B 25348397 N/A physical interaction ComPPI
SNX1 VPS29 11102511 24234451 25348397 physical association molecular sieving,physical interaction ComPPI,IntAct
SNX1 MED4 25348397 N/A physical interaction ComPPI
SNX1 CCDC88A 25348397 N/A physical interaction ComPPI
SNX1 C1ORF87 25348397 N/A physical interaction ComPPI
SNX1 CCDC102B 25348397 N/A physical interaction ComPPI
SNX1 MLX 25348397 N/A physical interaction ComPPI
SNX1 TMEM87A 25348397 N/A physical interaction ComPPI
SNX1 POTEB3 25348397 N/A physical interaction ComPPI
SNX1 KLHL10 25348397 N/A physical interaction ComPPI
SNX1 SLC35F2 25348397 N/A physical interaction ComPPI
SNX1 STAM 25348397 N/A physical interaction ComPPI
SNX1 SNX8 23085988 24234451 25348397 physical association pull down ComPPI,IntAct
SNX1 WASHC5 20923837 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SNX1 WASHC1 20923837 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
SNX1 SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 PLIN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 LIME1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 HCCS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 SDR16C5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 COQ3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 SYP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 REEP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 MPC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 SFT2D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 RHEX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNX1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SNX1 TGOLN2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
VPS35 SNX1 11102511 14525934 24234451 25348397 physical association experimental interaction detection,molecular sieving,physical interaction,in vivo,lexa b52 complementation ComPPI,HPRD,IntAct
ATP6V1C1 SNX1 25348397 N/A physical interaction ComPPI
SNX1 SNX1 11102511 11309204 14525934 23085988 24234451 physical association experimental interaction detection,x-ray crystallography,lexa b52 complementation HPRD,IntAct
ENO1 SNX1 24234451 30021884 physical association cross-linking study IntAct
SNX1 CLASP1 23477787 27898060 N/A N/A OmniPath

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