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GENE：SUGT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SUGT1
FullNmae SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16987
EnsembleID ENSG00000165416
Uniprot Q9Y2Z0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SUGT1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SUGT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SUGT1 GO:0000151,GO:0000776,GO:0005515,GO:0005634,GO:0005829,GO:0007051,GO:0014841,GO:0031647,GO:0032991,GO:0051087,GO:0051382,GO:0106222

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SUGT1 hsa:10910 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NOD1 SUGT1 17420470 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOD2 SUGT1 17420470 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 NLRP2 17420470 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 NLRP4 17420470 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 NLRP12 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 NLRC4 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 NLRP3 17435760 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
NLRP3 SUGT1 17435760 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 ITGB1BP2 18474241 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUGT1 HSF1 18358234 23180781 physical association electrophoretic mobility supershift assay InnateDB
SUGT1 HSPA4 17466273 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,solid phase assay InnateDB
HSP90AA1 SUGT1 16501598 17466273 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,solid phase assay InnateDB
SUGT1 HSP90B1 16501598 17466273 23180781 physical association anti tag coimmunoprecipitation,solid phase assay InnateDB
SUGT1 SKP1 16501598 18818696 23180781 physical association anti tag coimmunoprecipitation,isothermal titration calorimetry,pull down InnateDB
SKP1 SUGT1 18818696 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SUGT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SUGT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SUGT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SUGT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SUGT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SUGT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 SUGT1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002971AB SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002578DA SUGT1 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000079F78 SUGT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 SUGT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 SUGT1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 SUGT1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000034979B SUGT1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F SUGT1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 SUGT1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA SUGT1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 SUGT1 20371350 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 SUGT1 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 SUGT1 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 SUGT1 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 SUGT1 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC SUGT1 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000035D2F9 SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001925C1 SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB35 SUGT1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SUGT1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A SUGT1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B SUGT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 SUGT1 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000508C13 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A4ABF SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000002569A SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000021D08 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C02E4 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000118224 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000008AA34 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043D2C1 SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015188E SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005D986D SUGT1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PLK1 SUGT1 22135298 phosphorylation N/A PhosphoSite
SKP1 SUGT1 25361965 interaction type N/A PTMCode2
SUGT1 SKP1 25361965 interaction type N/A PTMCode2
S100A6 SUGT1 25361965 interaction type N/A PTMCode2
SUGT1 S100A6 25361965 interaction type N/A PTMCode2
S100P SUGT1 25361965 interaction type N/A PTMCode2
SUGT1 S100P 25361965 interaction type N/A PTMCode2
HSP90AB1 SUGT1 25361965 interaction type N/A PTMCode2
SUGT1 HSP90AB1 25361965 interaction type N/A PTMCode2
HSP90AA1 SUGT1 25361965 interaction type N/A PTMCode2
SUGT1 HSP90AA1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 SUGT1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L SUGT1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA8 SUGT1 25348397 N/A physical interaction ComPPI
ZNRD2 SUGT1 25348397 N/A physical interaction ComPPI
GLRX3 SUGT1 25348397 N/A physical interaction ComPPI
BAG3 SUGT1 25348397 N/A physical interaction ComPPI
S100B SUGT1 25348397 N/A in vitro ComPPI
S100P SUGT1 25348397 N/A physical interaction,in vitro ComPPI
S100A4 SUGT1 25348397 N/A physical interaction ComPPI
CFL1 SUGT1 25348397 N/A physical interaction ComPPI
LRCH4 SUGT1 24234451 24255178 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SKP1 SUGT1 18818696 24234451 25348397 N/A isothermal titration calorimetry,physical interaction,in vitro ComPPI,IntAct
H2BC4 SUGT1 25348397 N/A physical interaction ComPPI
KEAP1 SUGT1 25348397 N/A physical interaction ComPPI
HSP90AB1 SUGT1 25348397 N/A physical interaction ComPPI
CENPH SUGT1 25348397 N/A physical interaction ComPPI
PAXIP1 SUGT1 25348397 N/A physical interaction ComPPI
AIP SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90AA1 SUGT1 19875381 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NTRK1 SUGT1 25348397 N/A physical interaction ComPPI
PTPRF SUGT1 25348397 N/A physical interaction ComPPI
PIR SUGT1 25348397 N/A physical interaction ComPPI
BUB3 SUGT1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSP90B1 SUGT1 25348397 N/A physical interaction ComPPI
PLK1 SUGT1 25348397 N/A physical interaction ComPPI
PSMA1 SUGT1 25348397 N/A physical interaction ComPPI
KSR2 SUGT1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
CSNK2A1 SUGT1 25348397 N/A physical interaction ComPPI
EEF1A1 SUGT1 25348397 N/A physical interaction ComPPI
CACYBP SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EVC2 SUGT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK6 SUGT1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PARD6A SUGT1 14676191 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4A SUGT1 25348397 N/A physical interaction ComPPI
NR4A1 SUGT1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FKBP4 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA4 SUGT1 25348397 N/A physical interaction ComPPI
SKP2 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR12 SUGT1 25348397 N/A physical interaction ComPPI
HDAC11 SUGT1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP8 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PMF1 SUGT1 25348397 N/A physical interaction ComPPI
RNF41 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOD1 SUGT1 17420470 23935490 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP5C SUGT1 24234451 25348397 28330616 association pull down ComPPI,IntAct
NLRP4 SUGT1 17420470 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6KB2 SUGT1 25348397 N/A physical interaction ComPPI
CLIC4 SUGT1 25348397 N/A physical interaction ComPPI
DDX39A SUGT1 25348397 N/A physical interaction ComPPI
FBXL2 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP3K3 SUGT1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PSMB1 SUGT1 25348397 N/A physical interaction ComPPI
S100A6 SUGT1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PPEF2 SUGT1 25348397 N/A physical interaction ComPPI
AURKB SUGT1 25348397 N/A physical interaction ComPPI
NOD2 SUGT1 17420470 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MIS12 SUGT1 25348397 N/A physical interaction ComPPI
DSN1 SUGT1 25348397 N/A physical interaction ComPPI
NLRP3 SUGT1 25348397 N/A physical interaction ComPPI
NPHP4 SUGT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MED20 SUGT1 25348397 N/A physical interaction ComPPI
NLRP2 SUGT1 17420470 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RSU1 SUGT1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 PHLPP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 HSP90AA2P 25348397 N/A physical interaction ComPPI
SUGT1 TONSL 21113133 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SUGT1 CEP97 24234451 25036637 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 NSL1 25348397 N/A physical interaction ComPPI
SUGT1 AHCYL1 25348397 N/A physical interaction ComPPI
SUGT1 PSMD3 25348397 N/A physical interaction ComPPI
SUGT1 PPIL3 25348397 N/A physical interaction ComPPI
SUGT1 LRCH3 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 MYG1 25348397 N/A physical interaction ComPPI
SUGT1 CHORDC1 25348397 N/A physical interaction ComPPI
SUGT1 IDH1 25348397 N/A physical interaction ComPPI
SUGT1 SMAP 25348397 N/A physical interaction ComPPI
SUGT1 FKBP5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 HSF4 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 RPAP3 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 LRRC40 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUGT1 WDR76 25348397 N/A physical interaction ComPPI
SUGT1 WDR90 25348397 N/A physical interaction ComPPI
SUGT1 LRRC39 25348397 N/A physical interaction ComPPI
SUGT1 LRRC42 25348397 N/A physical interaction ComPPI
SUGT1 ALDH1L2 25348397 N/A physical interaction ComPPI
SUGT1 KLHL18 25348397 N/A physical interaction ComPPI
SUGT1 LLGL2 25348397 N/A physical interaction ComPPI
SUGT1 AMBRA1 25348397 N/A physical interaction ComPPI
SUGT1 PNPO 25348397 N/A physical interaction ComPPI
SUGT1 SEPHS1 25348397 N/A physical interaction ComPPI
SUGT1 H2BC11 25348397 N/A physical interaction ComPPI
SUGT1 OFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 MKS1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 CEP170 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 CEP104 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 POC1A 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 STIL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUGT1 EEF1A1P5 25348397 N/A physical interaction ComPPI
SUGT1 PHLPP2 25348397 N/A physical interaction ComPPI
SUGT1 DUSP8 25348397 N/A physical interaction ComPPI
SUGT1 LRRC57 25348397 N/A physical interaction ComPPI
SUGT1 FBXL14 25348397 N/A physical interaction ComPPI
SUGT1 LRRC10 25348397 N/A physical interaction ComPPI
SUGT1 NEU4 25348397 N/A physical interaction ComPPI
SUGT1 LRRC8B 25348397 N/A physical interaction ComPPI
SUGT1 CYLD 25348397 N/A physical interaction ComPPI
SUGT1 LLGL1 24234451 24366813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NEK8 SUGT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PTGER4 SUGT1 24234451 28298427 physical association ubiquitin reconstruction IntAct
PLK1 SUGT1 21864708 22869522 27898060 N/A N/A OmniPath
NOD2 SUGT1 17420470 17435760 27898060 N/A N/A OmniPath
SUGT1 NOD2 17420470 17435760 27898060 N/A N/A OmniPath
HSP90B1 SUGT1 16501598 17466273 27898060 N/A N/A OmniPath
SUGT1 NLRP3 17435760 27898060 stimulant N/A OmniPath
SKP1 SUGT1 12746458 16501598 18818696 26344197 27898060 N/A N/A OmniPath
SUGT1 SKP1 12746458 16501598 18818696 26344197 27898060 N/A N/A OmniPath
SUGT1 NLRC4 17435760 27898060 N/A N/A OmniPath
NLRP4 SUGT1 17420470 17435760 27898060 N/A N/A OmniPath
SUGT1 NLRP4 17420470 17435760 27898060 N/A N/A OmniPath
SUGT1 ITGB1BP2 18474241 27898060 N/A N/A OmniPath
SUGT1 NLRP12 17435760 27898060 N/A N/A OmniPath
NOD1 SUGT1 17420470 17435760 27898060 N/A N/A OmniPath
SUGT1 NOD1 17420470 17435760 27898060 stimulant N/A OmniPath
HSPA4 SUGT1 17466273 27898060 N/A N/A OmniPath
SUGT1 HSPA4 17466273 27898060 N/A N/A OmniPath
SUGT1 NLRP2 17420470 17435760 27898060 N/A N/A OmniPath

Visualization










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