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GENE：TNFRSF4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFRSF4
FullNmae TNF receptor superfamily member 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11918
EnsembleID ENSG00000186827
Uniprot P43489

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFRSF4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNFRSF4 GO:0001618,GO:0002639,GO:0005031,GO:0005515,GO:0005886,GO:0006954,GO:0006955,GO:0009897,GO:0009986,GO:0030890,GO:0033209,GO:0042098,GO:0043433,GO:0045892,GO:0046718

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFRSF4 hsa:7293 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TNFSF4 TNFRSF4 10626891 22437870 26192618 9378971 interaction type N/A ACSN
TRAF3 TNFRSF4 15941918 23180781 9488716 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF4 TNFRSF9 15941918 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF1 TNFRSF4 15941918 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF4 TRAF2 15941918 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF4 TNFRSF4 15941918 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF4 TRAF5 15941918 23180781 physical association anti tag coimmunoprecipitation InnateDB
TNFRSF4 TNFSF4 16905106 23180781 physical association x-ray crystallography InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 TNFRSF4 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TNFRSF4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC TNFRSF4 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TNFRSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNFRSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TNFRSF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TRAF3 TNFRSF4 14525934 25348397 9418902 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TRAF1 TNFRSF4 14525934 15941918 25348397 9488716 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TRAF2 TNFRSF4 14525934 25348397 9418902 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TRAF5 TNFRSF4 14525934 25348397 9488716 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SIVA1 TNFRSF4 12478477 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TRAF4 TNFRSF4 14525934 15941918 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TNFRSF4 TNFSF4 12134113 14525934 16905106 24234451 25348397 N/A affinity chromatography technology,experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,in vivo ComPPI,HPRD,IntAct
TNFRSF4 TNFRSF9 14525934 15941918 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TNFRSF4 TRAF2 10518213 15941918 27898060 9418902 N/A N/A OmniPath
TRAF2 TNFRSF4 10518213 15941918 27898060 9418902 N/A N/A OmniPath
TNFRSF4 TRAF3 15941918 27898060 9418902 9488716 N/A N/A OmniPath
TRAF3 TNFRSF4 15941918 27898060 9418902 9488716 N/A N/A OmniPath
TNFRSF4 TRAF5 15941918 27898060 9488716 N/A N/A OmniPath
TNFSF4 TNFRSF4 12134113 16905106 27898060 8076595 9488716 stimulant N/A OmniPath

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