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GENE：TWIST2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TWIST2
FullNmae twist family bHLH transcription factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20670
EnsembleID ENSG00000233608
Uniprot Q8WVJ9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TWIST2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TWIST2 GO:0000977,GO:0000981,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006357,GO:0014070,GO:0030154,GO:0030335,GO:0032502,GO:0032868,GO:0043066,GO:0045668,GO:0045892,GO:0046983

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TWIST2 hsa:117581 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CEBPA TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 TWIST2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A TWIST2 21931630 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 TWIST2 17909010 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TWIST2 SREBF1 14525934 14654692 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
TWIST2 MEF2C 11809751 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
TWIST2 TWIST1 25348397 N/A physical interaction ComPPI
TWIST2 ETS2 18598946 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TWIST2 TCF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TWIST2 CCM2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping,validated two hybrid ComPPI,IntAct
TWIST2 CRK 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TWIST2 PLCG2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TWIST2 TP53 22975381 24234451 25348397 physical association pull down ComPPI,IntAct
TWIST2 GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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