Gene Information gene info

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GENE：UNC5CL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UNC5CL
FullNmae unc-5 family C-terminal like
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21203
EnsembleID ENSG00000124602
Uniprot Q8IV45

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UNC5CL mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UNC5CL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UNC5CL GO:0005042,GO:0005515,GO:0005737,GO:0008233,GO:0016020,GO:0038007,GO:0043123,GO:0043123,GO:0046330,GO:0046330

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRAK4 UNC5CL 22158417 23180781 physical association anti tag coimmunoprecipitation InnateDB
UNC5CL IRAK1 22158417 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 UNC5CL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 UNC5CL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UNC5CL 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UNC5CL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 UNC5CL 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000081D1E UNC5CL 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001310DE UNC5CL 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NFKB1 UNC5CL 25361965 interaction type N/A PTMCode2
UNC5CL NFKB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BAG3 UNC5CL 25348397 N/A physical interaction ComPPI
NUMB UNC5CL 25348397 N/A physical interaction ComPPI
RELA UNC5CL 25348397 N/A physical interaction,in vivo ComPPI
BICD2 UNC5CL 25348397 N/A physical interaction ComPPI
CHEK1 UNC5CL 25348397 N/A physical interaction ComPPI
NFKB1 UNC5CL 25348397 N/A physical interaction,in vivo ComPPI
INSR UNC5CL 25348397 N/A physical interaction ComPPI
LRRC41 UNC5CL 25348397 N/A physical interaction ComPPI
NUMBL UNC5CL 25348397 N/A physical interaction ComPPI
IGF1R UNC5CL 25348397 N/A physical interaction ComPPI
POM121 UNC5CL 25348397 N/A physical interaction ComPPI
KDM8 UNC5CL 25348397 N/A physical interaction ComPPI
CHORDC1 UNC5CL 25348397 N/A physical interaction ComPPI
UNC5CL FLVCR1 25348397 N/A physical interaction ComPPI
UNC5CL USP22 25348397 N/A physical interaction ComPPI
UNC5CL DDRGK1 25348397 N/A physical interaction ComPPI
UNC5CL CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UNC5CL KRTAP13-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UNC5CL ZMYND12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UNC5CL PGAM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UNC5CL KRTAP6-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UNC5CL IRAK1 22158417 27898060 N/A N/A OmniPath
UNC5CL IRAK4 22158417 27898060 N/A N/A OmniPath

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