Gene Information gene info

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GENE：USP14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP14
FullNmae ubiquitin specific peptidase 14
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12612
EnsembleID ENSG00000101557
Uniprot P54578

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP14 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
USP14 GO:0000502,GO:0004197,GO:0004843,GO:0004843,GO:0004866,GO:0005515,GO:0005829,GO:0005829,GO:0005886,GO:0007268,GO:0009986,GO:0016579,GO:0016579,GO:0031410,GO:0043161,GO:0045087,GO:0045202,GO:0050920,GO:0061136,GO:0061136,GO:0061578,GO:0070062,GO:0070628,GO:0070628,GO:1903070

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
USP14 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 USP14 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 USP14 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 USP14 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IGF1R USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 USP14 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 USP14 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 USP14 19074876 22100165 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS000003ABC4 USP14 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000029D9F1 USP14 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 USP14 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000568FF8 USP14 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC USP14 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C USP14 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 USP14 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 USP14 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 USP14 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 USP14 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001F373E USP14 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006A1CB USP14 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 USP14 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD USP14 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003CF1AD USP14 25416803 27448976 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 USP14 22135298 phosphorylation N/A PhosphoSite
AKT1 USP14 22135298 phosphorylation N/A PhosphoSite
PSMA6 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMA6 25361965 interaction type N/A PTMCode2
PSMC4 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMC4 25361965 interaction type N/A PTMCode2
PSMD8 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD8 25361965 interaction type N/A PTMCode2
USP14 PSMD11 25361965 interaction type N/A PTMCode2
PSMD11 USP14 25361965 interaction type N/A PTMCode2
USP14 FANCC 25361965 interaction type N/A PTMCode2
FANCC USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMC3 25361965 interaction type N/A PTMCode2
PSMC3 USP14 25361965 interaction type N/A PTMCode2
USP14 CDKL2 25361965 interaction type N/A PTMCode2
CDKL2 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 USP14 25361965 interaction type N/A PTMCode2
USP14 USP7 25361965 interaction type N/A PTMCode2
USP7 USP14 25361965 interaction type N/A PTMCode2
USP14 PIPSL 25361965 interaction type N/A PTMCode2
PIPSL USP14 25361965 interaction type N/A PTMCode2
USP14 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 USP14 25361965 interaction type N/A PTMCode2
USP14 ERG 25361965 interaction type N/A PTMCode2
ERG USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD14 25361965 interaction type N/A PTMCode2
PSMD14 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 USP14 25361965 interaction type N/A PTMCode2
PSMC1 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMC1 25361965 interaction type N/A PTMCode2
CD68 USP14 25361965 interaction type N/A PTMCode2
USP14 CD68 25361965 interaction type N/A PTMCode2
PSMD7 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD7 25361965 interaction type N/A PTMCode2
TXNL1 USP14 25361965 interaction type N/A PTMCode2
USP14 TXNL1 25361965 interaction type N/A PTMCode2
PSMD10 USP14 25361965 interaction type N/A PTMCode2
USP14 PSMD10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HNRNPK USP14 25348397 N/A physical interaction ComPPI
SH3GLB1 USP14 25348397 N/A physical interaction ComPPI
VIM USP14 25348397 N/A physical interaction ComPPI
PSMC3 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC6 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD14 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD7 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCDC22 USP14 25348397 N/A physical interaction ComPPI
AHNAK2 USP14 25348397 N/A physical interaction ComPPI
BCL2L1 USP14 25348397 25429837 26710889 27898060 N/A physical interaction ComPPI,OmniPath
VPS37B USP14 25348397 N/A physical interaction ComPPI
AR USP14 25348397 N/A physical interaction ComPPI
COPS5 USP14 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
USP7 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA3 USP14 25348397 N/A physical interaction ComPPI
RAP1GDS1 USP14 25348397 N/A physical interaction ComPPI
PSMD11 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC USP14 25348397 N/A physical interaction ComPPI
UBE2N USP14 25348397 N/A physical interaction ComPPI
ARFIP1 USP14 25348397 N/A physical interaction ComPPI
NTRK1 USP14 25348397 N/A physical interaction ComPPI
CNTN1 USP14 25348397 N/A physical interaction ComPPI
PSMA6 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPL USP14 25348397 N/A physical interaction ComPPI
PSMD8 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
NDRG1 USP14 25348397 N/A physical interaction ComPPI
AHNAK USP14 25348397 N/A physical interaction ComPPI
PSMD1 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 USP14 25348397 N/A physical interaction ComPPI
PSMC5 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UNC45A USP14 25348397 N/A physical interaction ComPPI
RAD23A USP14 25348397 N/A physical interaction ComPPI
FANCC USP14 25348397 N/A physical interaction ComPPI
HTT USP14 25348397 N/A physical interaction ComPPI
PSMC4 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB1 USP14 25348397 N/A physical interaction ComPPI
WDR12 USP14 25348397 N/A physical interaction ComPPI
CCNB1 USP14 25348397 N/A physical interaction ComPPI
PSMD2 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD10 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD4 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SEM1 USP14 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB5 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CXCR4 USP14 25348397 N/A physical interaction ComPPI
TRIM25 USP14 25348397 N/A physical interaction ComPPI
PSMC1 USP14 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DERL1 USP14 25348397 N/A physical interaction ComPPI
RGPD5 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GABBR1 USP14 25348397 N/A physical interaction ComPPI
PPP3R1 USP14 19896943 24234451 25348397 association pull down ComPPI,IntAct
ERN1 USP14 25348397 N/A physical interaction ComPPI
RPL23 USP14 25348397 N/A physical interaction ComPPI
PPP3CA USP14 19896943 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct,OmniPath
RNF11 USP14 25348397 N/A physical interaction ComPPI
UBE2V2 USP14 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
XPO7 USP14 25348397 N/A physical interaction ComPPI
CNDP2 USP14 25348397 N/A physical interaction ComPPI
UCHL5 USP14 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP21 USP14 25348397 N/A physical interaction ComPPI
ECHS1 USP14 25348397 N/A physical interaction ComPPI
ADRM1 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD13 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD12 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC2 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL30 USP14 25348397 N/A physical interaction ComPPI
PSMD6 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA2 USP14 25348397 N/A physical interaction ComPPI
TXNL1 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSS USP14 25348397 N/A physical interaction ComPPI
SRPRB USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP28 USP14 25348397 N/A physical interaction ComPPI
UBE3A USP14 25348397 N/A physical interaction ComPPI
SEM1 USP14 25348397 N/A physical interaction ComPPI
CHMP7 USP14 25348397 N/A physical interaction ComPPI
NXF1 USP14 25348397 N/A physical interaction ComPPI
PSMD3 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PFAS USP14 25348397 N/A physical interaction ComPPI
HLA-B USP14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USP15 USP14 25348397 N/A physical interaction ComPPI
USP14 UNK 25348397 N/A physical interaction ComPPI
USP14 NAPRT 25348397 N/A physical interaction ComPPI
HSPD1 USP14 24234451 30021884 physical association cross-linking study IntAct
GABRA1 USP14 19759851 27898060 N/A N/A OmniPath
CDK1 USP14 26523394 27898060 N/A N/A OmniPath

Visualization










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