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GENE：VAV1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VAV1
FullNmae vav guanine nucleotide exchange factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12657
EnsembleID ENSG00000141968
Uniprot P15498

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VAV1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VAV1 GO:0001784,GO:0005085,GO:0005085,GO:0005085,GO:0005515,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0006955,GO:0007186,GO:0007229,GO:0008361,GO:0016477,GO:0030168,GO:0030217,GO:0030593,GO:0031295,GO:0035556,GO:0038095,GO:0038096,GO:0043087,GO:0043087,GO:0045954,GO:0046872,GO:0048010,GO:0051056,GO:0071466,GO:0072593,GO:0140031

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VAV1 hsa:7409 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04510 Focal adhesion - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
VAV1 hsa:7409 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
VAV1 hsa:7409 path:hsa05135 Yersinia infection - Homo sapiens (human)
VAV1 hsa:7409 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
VAV1 hsa:7409 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
VAV1 DNM2 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 15696170 16887996 19909365 20189481 22513334 22786724 22952938 25234227 25355530 25539813 26192618 26552706 8189062 8226994 9438848 association N/A ACSN
VAV1 PXN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 TUBGCP2 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 TUBGCP3 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 TUBGCP4 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 TUBGCP5 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 TUBGCP6 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 ICAM1 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 TLN1 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
CD28 VAV1 10426994 11034388 11907067 1313950 15197224 15536084 16713974 22437870 23109003 26192618 7523569 9359474 interaction type,chemical activation reaction N/A ACSN,SignaLink
FLNA VAV1 16849481 21277899 26192618 27242793 interaction type N/A ACSN
LCP2 VAV1 12640133 19909365 20189481 21536650 22786724 23474202 23620508 24343663 24584089 26192618 9765283 interaction type N/A ACSN
CBLB VAV1 10426994 10646608 11526404 11907067 15536084 16713974 19592273 26192618 interaction type N/A ACSN
LCK VAV1 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
CD4 VAV1 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
VAV1 LAT 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
VAV1 PLCG1 10077632 10395673 10646608 10679059 10714681 10849438 10898494 11007481 11080163 11278486 11340169 11526404 11698448 11709089 11754814 11804587 11994416 12094222 12165654 12186560 12573241 12616499 12626562 12670394 12740575 12885870 12917349 12941616 14764585 15169881 16887996 17540168 19909365 20189481 22513334 22786724 22952938 23109003 24243840 25355530 25539813 26192618 26552706 29145629 7518558 8189062 8226994 8629002 8630736 8673706 8986718 9099726 9438848 interaction type,physical association,chemical activation reaction inferred by curator ACSN,Reactome,SignaLink
VAV1 GRAP 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 23331499 25355530 25539813 26192618 26552706 7809090 8189062 8226994 9438848 interaction type,stimulation N/A ACSN,SignaLink
FYN VAV1 10591186 10648627 10849438 12218089 12670394 12731048 15699036 15886116 18295596 19290918 19909365 20814939 21378271 22683124 22863785 24440149 26192618 27192565 29145629 9738502 9822663 interaction type,enzymatic reaction,physical association inferred by curator ACSN,Reactome
GRB2 VAV1 10077632 10086337 10426994 10567412 10646608 10679059 10714681 10811803 10849438 10898494 10982827 11080163 11447289 11526404 11698448 11754814 11777939 11777960 11907067 11994416 12094222 12165654 12175651 12186560 12616499 12626562 12640133 12740575 12885870 12917349 14764585 15169881 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 8551221 9438848 interaction type N/A ACSN
CRK VAV1 15308668 16000375 16076871 18835194 22464172 26192618 interaction type N/A ACSN
SH2D1B VAV1 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 26192618 7890616 9535722 interaction type N/A ACSN
SLAMF7 VAV1 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 26192618 7890616 9535722 interaction type N/A ACSN
PTK2B VAV1 10679059 12626562 26192618 9763606 interaction type N/A ACSN
VAV1 RHOA 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14757747 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 23109003 25355530 25539813 26192618 26552706 8189062 8226994 9438848 9695188 interaction type,chemical activation reaction N/A ACSN,SignaLink
CBL VAV1 11353765 15169881 18835194 20189481 26192618 interaction type N/A ACSN
PTPN6 VAV1 12176909 12773515 12917349 15240681 15713798 22513334 22952938 25355530 26192618 26667266 27474009 8976179 8986721 9765283 interaction type N/A ACSN
VAV1 CDC42 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14757747 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 23109003 25355530 25539813 26192618 26552706 8189062 8226994 9438848 9695188 interaction type,chemical activation reaction N/A ACSN,SignaLink
HRAS VAV1 1377053 1569084 23180781 29145629 8554611 phosphorylation reaction,enzymatic reaction inferred by curator,protein kinase assay InnateDB,Reactome
VAV1 LCP2 11331248 15388330 23180781 physical association gst pull down InnateDB
VAV1 CHUK 12626540 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFKBIA VAV1 12626540 23180781 phosphorylation reaction anti tag coimmunoprecipitation InnateDB
VAV1 SYK 11331248 12573241 16546099 23180781 23331499 24243840 29145629 7518558 8629002 8630736 8809042 8986718 phosphorylation reaction,enzymatic reaction,stimulation,physical association anti tag coimmunoprecipitation,gst pull down,inferred by curator,protein kinase assay InnateDB,Reactome,SignaLink
VAV1 CBL 11331248 23180781 23331499 9200440 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
VAV1 PIK3R1 10706702 11331248 15187135 23180781 29145629 7528218 7687428 7687539 7691807 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
VAV1 TYK2 23180781 9038355 physical association anti tag coimmunoprecipitation InnateDB
VAV1 MERTK 12920122 23180781 physical association two hybrid,pull down InnateDB
MAPK1 VAV1 23180781 9013873 physical association anti tag coimmunoprecipitation InnateDB
IL6ST VAV1 23180781 9013873 physical association pull down InnateDB
VAV1 GRB2 23180781 9013873 physical association anti tag coimmunoprecipitation InnateDB
VAV1 SPI1 19747912 23180781 physical association anti tag coimmunoprecipitation InnateDB
VAV1 ITGAM 19747912 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
VAV1 EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
VAV1 VAV1 11804587 29145629 9705280 physical association inferred by curator Reactome
CD19 VAV1 10706702 15187135 29145629 7528218 7687428 7687539 7691807 physical association inferred by curator Reactome
PIK3CD VAV1 10706702 15187135 29145629 7528218 7687428 7687539 7691807 physical association inferred by curator Reactome
LYN VAV1 29145629 7539782 8677749 9162069 9209406 physical association inferred by curator Reactome
VAV1 IRS2 29145629 7539782 8677749 9162069 9209406 physical association inferred by curator Reactome
IGKC VAV1 16546099 29145629 8809042 8986718 physical association inferred by curator Reactome
VAV1 SOS1 10395673 11007481 11278486 11340169 11804587 12573241 12670394 17540168 24243840 29145629 7518558 8629002 8630736 8673706 8986718 9099726 physical association inferred by curator Reactome
VAV1 PLCG2 10395673 11007481 11278486 11340169 11804587 12573241 12670394 17540168 24243840 29145629 7518558 8629002 8630736 8673706 8986718 9099726 physical association inferred by curator Reactome
VAV1 BTK 12573241 24243840 29145629 7518558 8629002 8630736 enzymatic reaction,physical association inferred by curator Reactome
KRAS VAV1 1377053 1569084 29145629 enzymatic reaction inferred by curator Reactome
NRAS VAV1 1377053 1569084 29145629 enzymatic reaction inferred by curator Reactome
MERTK VAV1 12920122 23331499 stimulation N/A SignaLink
ABL1 VAV1 11790798 23331499 stimulation N/A SignaLink
VAV1 PRKCQ 10725744 11956228 15802604 23109003 23331499 stimulation,chemical activation reaction N/A SignaLink,SignaLink
VAV1 MAPK1 23331499 9013873 stimulation N/A SignaLink
ITK VAV1 12186560 23109003 chemical activation reaction N/A SignaLink
LAT VAV1 12186560 23109003 chemical activation reaction N/A SignaLink
ZAP70 VAV1 11859198 14757747 15751964 23109003 chemical activation reaction N/A SignaLink
SH3BP2 VAV1 11859198 14757747 15751964 23109003 chemical activation reaction N/A SignaLink
VAV1 PRKCB 11956228 15802604 23109003 chemical activation reaction N/A SignaLink
VAV1 PRKCD 11956228 15802604 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 VAV1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 VAV1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ELK1 VAV1 N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN VAV1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYB VAV1 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 VAV1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 VAV1 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
ABL1 VAV1 22135298 phosphorylation N/A PhosphoSite
LCK VAV1 22135298 phosphorylation N/A PhosphoSite
VAV1 RAC1 25361965 interaction type N/A PTMCode2
RAC1 VAV1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HNRNPK VAV1 14525934 25348397 7862126 8051112 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
LCP2 VAV1 10347175 11331248 14525934 21725281 24234451 25348397 8673706 9047237 9341187 association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CDC42 VAV1 11287617 14525934 18511940 24234451 25348397 N/A experimental interaction detection,fluorescence technology,physical interaction,in vivo ComPPI,HPRD,IntAct
LAT VAV1 11368773 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
S100B VAV1 10394361 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TUBB VAV1 25348397 27898060 8530437 9880513 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
EMD VAV1 25348397 N/A physical interaction ComPPI
TYK2 VAV1 10673353 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 VAV1 14525934 25348397 8632004 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RAC1 VAV1 14525934 16397238 18511940 24234451 25348397 N/A experimental interaction detection,fluorescence technology,x-ray crystallography,physical interaction,in vivo ComPPI,HPRD,IntAct
CRK VAV1 14525934 24234451 25348397 8621483 physical association coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
ERBB2 VAV1 25348397 N/A physical interaction ComPPI
CBL VAV1 11133830 14525934 24234451 25348397 9200440 association experimental interaction detection,pull down,physical interaction,genetic,in vitro,in vivo ComPPI,HPRD,IntAct
VAV1 PRLR 11328862 14525934 25348397 27898060 7768923 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
VAV1 MAPK1 14525934 25348397 8900182 9013873 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 RHOG 12376551 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAV1 HRAS 14525934 25348397 8554611 N/A experimental interaction detection,in vivo ComPPI,HPRD
VAV1 BTK 14525934 25348397 9201297 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 SYK 14525934 25348397 8986718 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
VAV1 SHB 12084069 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAV1 PRKCQ 10725744 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 TEC 14525934 25348397 7651724 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAV1 IL6ST 14525934 25348397 9013873 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 SLA 10662792 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
VAV1 PTK2B 10867021 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAV1 EZH2 10780782 14525934 15882624 25348397 27898060 8649418 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
VAV1 ZYX 14525934 25348397 8622875 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
VAV1 SH3BP2 11390470 14525934 15345594 17306257 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cosedimentation through density gradient,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
VAV1 SIAH2 10207103 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
VAV1 ARHGDIB 10664460 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
VAV1 SOCS1 10022833 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
VAV1 AOC3 1375396 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
VAV1 NEK3 14525934 15618286 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
VAV1 CBLB 11857085 14525934 25348397 27898060 9399639 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
VAV1 BLNK 14525934 25348397 9697839 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 PAG1 10790433 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
VAV1 MET 14525934 15546961 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
VAV1 CASP3 10713703 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
VAV1 ARHGDIA 10664460 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAV1 ACTA1 11839310 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
VAV1 HCK 14525934 25348397 9400828 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAV1 CXCR4 14525934 15618472 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
VAV1 TUBA4A 14525934 25348397 8530437 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
VAV1 XRCC5 10673353 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 ZNF655 14525934 15558030 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
VAV1 ZAP70 14525934 16339550 24234451 25348397 7798261 9151714 association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
VAV1 GRB2 14525934 15558030 16339550 18692475 24234451 25348397 29997244 7809090 physical association bioluminescence resonance energy transfer,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
VAV1 MERTK 12920122 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
VAV1 SHC1 14525934 15688026 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
VAV1 PTPN22 14525934 16461343 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
VAV1 EGFR 10938113 14525934 24234451 24658140 25348397 physical association experimental interaction detection,ubiquitin reconstruction,physical interaction,in vivo ComPPI,HPRD,IntAct
VAV1 EPOR 14525934 25348397 9162069 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
VAV1 FYN 14525934 25348397 9822663 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAV1 INSR 14525934 25348397 7535775 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAV1 JAK2 14525934 25348397 7530656 9162069 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 BCR 11790798 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
VAV1 XRCC6 14525934 25348397 27898060 8524317 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
VAV1 LCK 10669745 14525934 17050525 24234451 25348397 association experimental interaction detection,pull down,in vivo ComPPI,HPRD,IntAct
VAV1 CD19 14525934 25348397 7528218 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VAV1 RAF1 14525934 25348397 8900182 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAV1 PLCG1 14525934 16467851 25348397 9891995 N/A experimental interaction detection,physical interaction ComPPI,HPRD
VAV1 PIK3R1 17050525 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
VAV1 JUN 25348397 N/A physical interaction ComPPI
VAV1 PDGFRB 25348397 N/A physical interaction ComPPI
VAV1 ABL1 19234221 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
VAV1 MAP2K1 25348397 N/A physical interaction ComPPI
VAV1 SIAH1 25348397 N/A physical interaction ComPPI
VAV1 PLCG2 25348397 N/A physical interaction ComPPI
VAV1 DOCK2 12393632 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
VAV1 SUZ12 25348397 N/A physical interaction ComPPI
VAV1 EED 25348397 N/A physical interaction ComPPI
VAV1 PHAX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VAV1 TUBA1A 25348397 N/A physical interaction ComPPI
VAV1 KHDRBS1 17855053 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
VAV1 FGFR1 25348397 N/A physical interaction ComPPI
VAV1 DOK1 25348397 N/A physical interaction ComPPI
VAV1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
VAV1 CD5 25348397 N/A physical interaction ComPPI
VAV1 SPI1 25348397 N/A physical interaction ComPPI
VAV1 ERBB3 25348397 N/A physical interaction ComPPI
VAV1 CD28 25348397 N/A physical interaction ComPPI
VAV1 MS4A2 25348397 N/A physical interaction ComPPI
VAV1 KLK7 25348397 N/A physical interaction ComPPI
VAV1 PLBD1 25348397 N/A physical interaction ComPPI
VAV1 NUB1 25348397 N/A physical interaction ComPPI
VAV1 SPECC1L 25348397 N/A physical interaction ComPPI
VAV1 SERPINA12 25348397 N/A physical interaction ComPPI
VAV1 AKAP2 25348397 N/A physical interaction ComPPI
VAV1 APLP2 25348397 N/A physical interaction ComPPI
VAV1 ACTBL2 25348397 N/A physical interaction ComPPI
VAV1 SDR9C7 25348397 N/A physical interaction ComPPI
VAV1 SERPINB2 25348397 N/A physical interaction ComPPI
VAV1 APBB2 25348397 N/A physical interaction ComPPI
VAV1 CDSN 25348397 N/A physical interaction ComPPI
VAV1 ACTA2 25348397 N/A physical interaction ComPPI
VAV1 CST6 25348397 N/A physical interaction ComPPI
VAV1 DNAJC1 25348397 N/A physical interaction ComPPI
VAV1 SBSN 25348397 N/A physical interaction ComPPI
VAV1 DSG1 25348397 N/A physical interaction ComPPI
VAV1 ATP2B2 25348397 N/A physical interaction ComPPI
VAV1 CHEK1 25348397 N/A physical interaction ComPPI
VAV1 ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
VAV1 AR 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
VAV1 HAVCR2 24234451 25348397 26492563 association anti bait coimmunoprecipitation ComPPI,IntAct
RACGAP1 VAV1 10748082 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
RHOA VAV1 14525934 16397238 18511940 24234451 25348397 N/A experimental interaction detection,fluorescence technology,in vivo ComPPI,HPRD,IntAct
GAB1 VAV1 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
ITGB2 VAV1 19234221 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VAV1 TUBB2A 14525934 8530437 N/A experimental interaction detection HPRD
VAV1 DNM2 14525934 15696170 N/A experimental interaction detection HPRD
SMC4 VAV1 24234451 30021884 physical association cross-linking study IntAct
LCK VAV1 10636924 10669745 15699036 16285729 17050525 20028078 24332539 27898060 898671 stimulant N/A OmniPath
LYN VAV1 15699036 27898060 stimulant N/A OmniPath
FYN VAV1 11005864 11262396 27898060 9822663 stimulant N/A OmniPath
CHUK VAV1 12626540 27898060 N/A N/A OmniPath
HRAS VAV1 27898060 8554611 N/A N/A OmniPath
LAT VAV1 11368773 12186560 27898060 stimulant N/A OmniPath
VAV1 SPI1 19747912 27898060 N/A N/A OmniPath
IL6ST VAV1 27898060 9013873 stimulant N/A OmniPath
VAV1 PRKCQ 10725744 27898060 stimulant N/A OmniPath
VAV1 GRB2 10207103 15558030 16339550 18692475 27898060 7809090 8900182 9013873 9209406 stimulant N/A OmniPath
VAV1 TYK2 10673353 27898060 9038355 N/A N/A OmniPath
TYK2 VAV1 10673353 27898060 9038355 N/A N/A OmniPath
ABL1 VAV1 11790798 19234221 23325923 27898060 stimulant N/A OmniPath
PIK3R1 VAV1 11331248 17050525 27898060 9162069 9891995 stimulant N/A OmniPath
VAV1 CBL 11133830 11331248 12881521 16289966 16356860 18835194 19635790 27898060 920044 9200440 stimulant N/A OmniPath
CBL VAV1 11133830 11331248 12881521 16289966 16356860 18835194 19635790 27898060 920044 9200440 N/A N/A OmniPath
VAV1 MAPK1 27898060 8900182 9013873 stimulant N/A OmniPath
VAV1 LCP2 10347175 11331248 15388330 19635790 27898060 8673706 8703037 9047237 9341187 N/A N/A OmniPath
VAV1 SYK 11262396 11331248 27898060 8900182 8986718 stimulant N/A OmniPath
SYK VAV1 11262396 11331248 27898060 8900182 8986718 stimulant N/A OmniPath
VAV1 GRAP 27898060 7809090 stimulant N/A OmniPath
MERTK VAV1 12920122 27898060 stimulant N/A OmniPath

Visualization










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