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GENE：ABCG8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ABCG8
FullNmae ATP binding cassette subfamily G member 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13887
EnsembleID ENSG00000143921
Uniprot Q9H221

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ABCG8 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ABCG8 GO:0005515,GO:0005524,GO:0005886,GO:0005886,GO:0005886,GO:0007584,GO:0009410,GO:0010949,GO:0014850,GO:0015914,GO:0015918,GO:0016324,GO:0016324,GO:0016887,GO:0030299,GO:0033344,GO:0033344,GO:0033344,GO:0038183,GO:0042626,GO:0042626,GO:0042632,GO:0042632,GO:0043190,GO:0043235,GO:0043235,GO:0045796,GO:0046872,GO:0046982,GO:0055085,GO:0070328,GO:0120009,GO:0120020,GO:0120020,GO:0140359

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ABCG8 hsa:64241 path:hsa02010 ABC transporters - Homo sapiens (human)
ABCG8 hsa:64241 path:hsa04975 Fat digestion and absorption - Homo sapiens (human)
ABCG8 hsa:64241 path:hsa04976 Bile secretion - Homo sapiens (human)
ABCG8 hsa:64241 path:hsa04979 Cholesterol metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 ABCG8 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA ABCG8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ABCG8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ABCG8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ABCG8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ABCG8 18971253 21123766 trascriptional regulation,stimulation inferred by curator TFlink
NR5A2 ABCG8 15121760 trascriptional regulation,stimulation inferred by curator TFlink
SREBF2 ABCG8 21123766 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ABCG8 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00003003B4 ABCG8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA ABCG8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D ABCG8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 ABCG8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C ABCG8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 ABCG8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 ABCG8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000450F92 ABCG8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F ABCG8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB16 ABCG8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000605E00 ABCG8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 ABCG8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 ABCG8 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005586D0 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000315338 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C0FCB ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C770D ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C11BC ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000251D0B ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000939AF ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AB32B ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004818BD ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000555DA6 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045ED38 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027F5F3 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000031602A ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000547F6A ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001496AE ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004CCA62 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001F373E ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023F8DA ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045147B ABCG8 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NR4A1 ABCG8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LMNB1 ABCG8 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NOTCH3 ABCG8 25348397 N/A physical interaction ComPPI
MESD ABCG8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ABCG8 AKT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ABCG8 AGPAT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ABCG8 PTPRD 25348397 N/A physical interaction ComPPI

Visualization










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