Gene Information gene info

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GENE：RNF125

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF125
FullNmae ring finger protein 125
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21150
EnsembleID ENSG00000101695
Uniprot Q96EQ8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF125 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RNF125 GO:0000139,GO:0000209,GO:0000209,GO:0002039,GO:0002250,GO:0005515,GO:0006511,GO:0006511,GO:0008270,GO:0031624,GO:0032480,GO:0034098,GO:0034098,GO:0039536,GO:0043231,GO:0061630,GO:0061630,GO:1990830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RNF125 hsa:54941 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF125 UBE2L6 17460044 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
RNF125 DDX58 17460044 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,ubiquitination reaction InnateDB
RNF125 IFIH1 17460044 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,ubiquitination reaction InnateDB
RNF125 MAVS 17460044 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF125 UBA1 17460044 23180781 ubiquitination reaction,physical association ubiquitination reaction InnateDB
RNF125 UBE2D1 17460044 17990982 23180781 ubiquitination reaction,physical association two hybrid,ubiquitination reaction InnateDB
RNF125 UBE2D2 17460044 23180781 ubiquitination reaction,physical association ubiquitination reaction InnateDB
RNF125 UBE2D3 17460044 23180781 physical association ubiquitination reaction InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RNF125 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RNF125 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RNF125 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RNF125 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 RNF125 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000016C318 RNF125 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD RNF125 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000034979B RNF125 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 RNF125 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C RNF125 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFBE3 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 RNF125 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000100748 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000243FF1 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027352D RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D4175 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003FBC84 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000266339 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006372A RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C RNF125 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 RNF125 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000122F23 RNF125 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075B538 RNF125 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RNF125 UBE2L6 25361965 interaction type N/A PTMCode2
UBE2L6 RNF125 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2D1 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E2 RNF125 17460044 19549727 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D4 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D2 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2L3 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBC RNF125 25348397 N/A physical interaction ComPPI
UBE2N RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
JAK1 RNF125 25348397 N/A physical interaction ComPPI
EGFR RNF125 25348397 N/A physical interaction ComPPI
UBE2K RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D3 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2L6 RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL1RL2 RNF125 25348397 N/A physical interaction ComPPI
PML RNF125 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CHFR RNF125 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
USP2 RNF125 25348397 N/A physical interaction ComPPI
PCGF1 RNF125 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAVS RNF125 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBE2W RNF125 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM46 RNF125 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DDX58 RNF125 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
TP53 RNF125 25348397 25591766 27898060 N/A physical interaction ComPPI,OmniPath
RNF125 UBE2U 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RNF125 TRIM14 25348397 N/A physical interaction ComPPI
RNF125 IFIH1 17460044 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF125 MAVS 17460044 27898060 N/A N/A OmniPath
UBE2D3 RNF125 17460044 17719635 19549727 27898060 N/A N/A OmniPath
DDX58 RNF125 17460044 27898060 N/A N/A OmniPath
RNF125 DDX58 17460044 27898060 inhibition N/A OmniPath
RNF125 IFIH1 17460044 27898060 inhibition N/A OmniPath
IFIH1 RNF125 17460044 27898060 N/A N/A OmniPath
RNF125 UBE2D1 17460044 17990982 19549727 21571784 27898060 N/A N/A OmniPath
UBE2D2 RNF125 17460044 19549727 27898060 N/A N/A OmniPath
UBE2L6 RNF125 17460044 19549727 27898060 N/A N/A OmniPath

Visualization










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