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GENE：UCHL5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UCHL5
FullNmae ubiquitin C-terminal hydrolase L5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19678
EnsembleID ENSG00000116750
Uniprot Q9Y5K5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UCHL5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UCHL5 GO:0000723,GO:0003723,GO:0004843,GO:0004843,GO:0004843,GO:0004866,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0005829,GO:0006275,GO:0006281,GO:0006282,GO:0006310,GO:0006338,GO:0006511,GO:0016579,GO:0016579,GO:0016579,GO:0021670,GO:0030901,GO:0031011,GO:0031597,GO:0032435,GO:0033044,GO:0045739,GO:0045880,GO:0045893,GO:0045995,GO:0048853,GO:0051726,GO:0060382,GO:0061136,GO:0070628,GO:1904507

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UCHL5 hsa:51377 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP UCHL5 21832049 23180781 physical association protein array InnateDB
UCHL5 SMAD7 16027725 23331499 stimulation N/A SignaLink
UCHL5 TGFBR1 17052192 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
E2F4 UCHL5 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 UCHL5 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 UCHL5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UCHL5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UCHL5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000000EF0B UCHL5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A UCHL5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D UCHL5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A UCHL5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A UCHL5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 UCHL5 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KRT6B UCHL5 25348397 N/A physical interaction ComPPI
SNW1 UCHL5 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L UCHL5 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBED1 UCHL5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT19 UCHL5 25348397 N/A physical interaction ComPPI
TXN2 UCHL5 25348397 N/A physical interaction ComPPI
TFPT UCHL5 18922472 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FTL UCHL5 25348397 N/A physical interaction ComPPI
EIF1B UCHL5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ANP32B UCHL5 25348397 N/A physical interaction ComPPI
FTH1 UCHL5 25348397 N/A physical interaction ComPPI
ANXA1 UCHL5 25348397 N/A physical interaction ComPPI
SNRPA1 UCHL5 25348397 N/A physical interaction ComPPI
PSMC3 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC6 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTM3 UCHL5 25348397 N/A physical interaction ComPPI
ACTG1 UCHL5 25348397 N/A physical interaction ComPPI
CFL1 UCHL5 25348397 N/A physical interaction ComPPI
S100A14 UCHL5 25348397 N/A physical interaction ComPPI
PSMD14 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CASP14 UCHL5 25348397 N/A physical interaction ComPPI
SET UCHL5 25348397 N/A physical interaction ComPPI
PSMD7 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMNA UCHL5 25348397 N/A physical interaction ComPPI
ACTB UCHL5 25348397 N/A physical interaction ComPPI
CALM1 UCHL5 25348397 N/A physical interaction ComPPI
HBA1 UCHL5 25348397 N/A physical interaction ComPPI
PSMB2 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
INO80B UCHL5 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A16 UCHL5 25348397 N/A physical interaction ComPPI
ANXA4 UCHL5 25348397 N/A physical interaction ComPPI
H4C1 UCHL5 25348397 N/A physical interaction ComPPI
SMAD7 UCHL5 25348397 N/A physical interaction ComPPI
NACA UCHL5 25348397 N/A physical interaction ComPPI
SMAD2 UCHL5 25348397 N/A physical interaction ComPPI
SMAD3 UCHL5 25348397 N/A physical interaction ComPPI
PSMA3 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD11 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FLG UCHL5 25348397 N/A physical interaction ComPPI
CCNDBP1 UCHL5 25348397 N/A physical interaction ComPPI
ACTN4 UCHL5 25348397 N/A physical interaction ComPPI
YWHAZ UCHL5 25348397 N/A physical interaction ComPPI
PFN1 UCHL5 25348397 N/A physical interaction ComPPI
RAB7A UCHL5 25348397 N/A physical interaction ComPPI
CTSD UCHL5 25348397 N/A physical interaction ComPPI
UBC UCHL5 25348397 N/A physical interaction ComPPI
APOA1 UCHL5 25348397 N/A physical interaction ComPPI
PLA2G2A UCHL5 25348397 N/A physical interaction ComPPI
NTRK1 UCHL5 25348397 N/A physical interaction ComPPI
DSC3 UCHL5 25348397 N/A physical interaction ComPPI
RUVBL1 UCHL5 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN2 UCHL5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FHOD1 UCHL5 25348397 N/A physical interaction ComPPI
HSPA5 UCHL5 25348397 N/A physical interaction ComPPI
E2F1 UCHL5 25348397 26396186 27898060 N/A physical interaction ComPPI,OmniPath
PRDX1 UCHL5 25348397 N/A physical interaction ComPPI
PSMA1 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA6 UCHL5 16990800 18922472 19490896 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA5 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB9 UCHL5 25348397 N/A physical interaction ComPPI
XPO5 UCHL5 25348397 N/A physical interaction ComPPI
TXN UCHL5 25348397 N/A physical interaction ComPPI
CAPZA1 UCHL5 25348397 N/A physical interaction ComPPI
TUBA4A UCHL5 25348397 N/A physical interaction ComPPI
MAPK6 UCHL5 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMD8 UCHL5 11163772 14525934 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PSMB8 UCHL5 25348397 N/A physical interaction ComPPI
PSMD1 UCHL5 18922472 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PKM UCHL5 25348397 N/A physical interaction ComPPI
E2F2 UCHL5 25348397 N/A physical interaction ComPPI
ARG1 UCHL5 25348397 N/A physical interaction ComPPI
PSMC5 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UNC45A UCHL5 25348397 N/A physical interaction ComPPI
HUWE1 UCHL5 25348397 N/A physical interaction ComPPI
RAD23A UCHL5 25348397 N/A physical interaction ComPPI
TPI1 UCHL5 25348397 N/A physical interaction ComPPI
CSTA UCHL5 25348397 N/A physical interaction ComPPI
CYB5A UCHL5 25348397 N/A physical interaction ComPPI
YY1 UCHL5 18922472 24234451 25348397 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
DUSP14 UCHL5 25348397 N/A physical interaction ComPPI
PSMC4 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCRS1 UCHL5 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM63 UCHL5 25348397 N/A physical interaction ComPPI
ACTL6A UCHL5 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPB1 UCHL5 25348397 N/A physical interaction ComPPI
S100A7 UCHL5 25348397 N/A physical interaction ComPPI
NOS2 UCHL5 20634424 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD2 UCHL5 16990800 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PKP1 UCHL5 25348397 N/A physical interaction ComPPI
PRDX6 UCHL5 25348397 N/A physical interaction ComPPI
SERPINB12 UCHL5 25348397 N/A physical interaction ComPPI
RAD23B UCHL5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD10 UCHL5 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PJA1 UCHL5 25348397 N/A physical interaction ComPPI
PSMD4 UCHL5 17139257 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SEM1 UCHL5 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGM3 UCHL5 25348397 N/A physical interaction ComPPI
PSMB5 UCHL5 18922472 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SERPINB3 UCHL5 25348397 N/A physical interaction ComPPI
ACTR8 UCHL5 18922472 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMC1 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RGPD5 UCHL5 25348397 N/A physical interaction ComPPI
KDM1A UCHL5 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIM27 UCHL5 25348397 N/A physical interaction ComPPI
BRCA1 UCHL5 25348397 N/A physical interaction ComPPI
PSMB4 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CAP1 UCHL5 25348397 N/A physical interaction ComPPI
PSMB1 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT1 UCHL5 25348397 N/A physical interaction ComPPI
CBX7 UCHL5 25348397 N/A physical interaction ComPPI
PSMB3 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA4 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EEF2 UCHL5 25348397 N/A physical interaction ComPPI
EIF4A1 UCHL5 25348397 N/A physical interaction ComPPI
PLRG1 UCHL5 25348397 N/A physical interaction ComPPI
EEF1G UCHL5 25348397 N/A physical interaction ComPPI
TRIM55 UCHL5 25348397 N/A physical interaction ComPPI
PRDX3 UCHL5 25348397 N/A physical interaction ComPPI
TRIM54 UCHL5 25348397 N/A physical interaction ComPPI
PRPF19 UCHL5 25348397 N/A physical interaction ComPPI
RUVBL2 UCHL5 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 HAUS7 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
UCHL5 NFRKB 17721549 18922472 19615732 24234451 25194926 25348397 25416956 25702870 25702872 26186194 27898060 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
UCHL5 PSMB6 18922472 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 PSMC2 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 PSMD3 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 PSMD12 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 PSMD13 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 USP14 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 TXNL1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 PSMD6 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 USP12 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 PAAF1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 INO80E 18922472 19615732 21303910 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 INO80 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 ACTR5 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 INO80D 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 DSC1 25348397 N/A physical interaction ComPPI
UCHL5 ASPRV1 25348397 N/A physical interaction ComPPI
UCHL5 KRT80 25348397 N/A physical interaction ComPPI
UCHL5 POF1B 25348397 N/A physical interaction ComPPI
UCHL5 KRT73 25348397 N/A physical interaction ComPPI
UCHL5 KRT78 25348397 N/A physical interaction ComPPI
UCHL5 ANXA8 25348397 N/A physical interaction ComPPI
UCHL5 ANXA8L1 25348397 N/A physical interaction ComPPI
UCHL5 DSP 25348397 N/A physical interaction ComPPI
UCHL5 KRT28 25348397 N/A physical interaction ComPPI
UCHL5 KRT26 25348397 N/A physical interaction ComPPI
UCHL5 SERPINB5 25348397 N/A physical interaction ComPPI
UCHL5 EPPK1 25348397 N/A physical interaction ComPPI
UCHL5 CDSN 25348397 N/A physical interaction ComPPI
UCHL5 IDE 25348397 N/A physical interaction ComPPI
UCHL5 HBB 25348397 N/A physical interaction ComPPI
UCHL5 ANXA7 25348397 N/A physical interaction ComPPI
UCHL5 NACA 25348397 N/A physical interaction ComPPI
UCHL5 NACA4P 25348397 N/A physical interaction ComPPI
UCHL5 IVL 25348397 N/A physical interaction ComPPI
UCHL5 ANP32E 25348397 N/A physical interaction ComPPI
UCHL5 POTEF 25348397 N/A physical interaction ComPPI
UCHL5 KRT9 25348397 N/A physical interaction ComPPI
UCHL5 POTEE 25348397 N/A physical interaction ComPPI
UCHL5 ACTC1 25348397 N/A physical interaction ComPPI
UCHL5 APOB 25348397 N/A physical interaction ComPPI
UCHL5 ECHS1 25348397 N/A physical interaction ComPPI
UCHL5 PRDX2 25348397 N/A physical interaction ComPPI
UCHL5 SRXN1 25348397 N/A physical interaction ComPPI
UCHL5 CYB5B 25348397 N/A physical interaction ComPPI
UCHL5 KRT10 25348397 N/A physical interaction ComPPI
UCHL5 PSMA2 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 INO80C 18922472 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UCHL5 RFFL 25348397 N/A physical interaction ComPPI
UCHL5 USP28 25348397 N/A physical interaction ComPPI
UCHL5 APP 25348397 N/A physical interaction ComPPI
UCHL5 WDR61 25348397 N/A physical interaction ComPPI
UCHL5 RBCK1 25348397 N/A physical interaction ComPPI
UCHL5 TRIM46 25348397 N/A physical interaction ComPPI
UCHL5 KCMF1 25348397 N/A physical interaction ComPPI
UCHL5 RPS21 25348397 N/A physical interaction ComPPI
UCHL5 SEM1 25348397 N/A physical interaction ComPPI
UCHL5 UBE3A 25348397 N/A physical interaction ComPPI
UCHL5 MAP3K1 25348397 N/A physical interaction ComPPI
UCHL5 CCDC74B 25348397 N/A physical interaction ComPPI
UCHL5 FDFT1 25348397 N/A physical interaction ComPPI
UCHL5 RGPD8 25348397 N/A physical interaction ComPPI
UCHL5 HERC2 25348397 N/A physical interaction ComPPI
UCHL5 HERC2P3 25348397 N/A physical interaction ComPPI
UCHL5 CCDC92 25348397 N/A physical interaction ComPPI
UCHL5 ARMT1 25348397 N/A physical interaction ComPPI
UCHL5 PLCG1 25348397 N/A physical interaction ComPPI
UCHL5 TIPRL 25348397 N/A physical interaction ComPPI
UCHL5 CIAPIN1 25348397 N/A physical interaction ComPPI
UCHL5 COMMD4 25348397 N/A physical interaction ComPPI
UCHL5 XPNPEP1 25348397 N/A physical interaction ComPPI
UCHL5 E2F3 25348397 N/A physical interaction ComPPI
UCHL5 KDELR1 25348397 N/A physical interaction ComPPI
UCHL5 SLC17A2 25348397 N/A physical interaction ComPPI
UCHL5 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
ADRM1 UCHL5 14525934 16501559 16906146 16990800 17139257 18922472 19490896 19615732 21516116 24234451 25348397 25416956 colocalization,association,physical association anti tag coimmunoprecipitation,two hybrid,cosedimentation through density gradient,experimental interaction detection,pull down,physical interaction,two hybrid array,imaging technique,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PNP UCHL5 25348397 N/A physical interaction ComPPI
UBLCP1 UCHL5 25348397 N/A physical interaction ComPPI
ECPAS UCHL5 25348397 N/A physical interaction ComPPI
RNF20 UCHL5 25348397 N/A physical interaction ComPPI
ADRM1 UCHL5 16501559 16906146 16990800 17139257 18922472 19615732 20471946 21516116 22863883 24752541 25416956 25702870 26186194 26344197 27898060 stimulant N/A OmniPath
UCHL5 SMAD2 16027725 27898060 stimulant N/A OmniPath
UCHL5 TGFBR1 17052192 27898060 stimulant N/A OmniPath
UCHL5 SMAD3 16027725 27898060 stimulant N/A OmniPath
UCHL5 SMAD7 16027725 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009ADA90 UCHL5 27087310 direct interaction,inhibition N/A NPInter

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