GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
MACROD2 |
FullNmae |
mono-ADP ribosylhydrolase 2 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:16126 |
EnsembleID |
ENSG00000172264 |
Uniprot |
A1Z1Q3 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
MACROD2 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
MACROD2 |
GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0006974,GO:0006974,GO:0007420,GO:0009617,GO:0016798,GO:0019213,GO:0042278,GO:0042278,GO:0051725,GO:0140291,GO:0140291,GO:0140293,GO:0140293 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
MACROD2 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
YBX1 |
MACROD2 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
TFAP2C |
MACROD2 |
20629094
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
MACROD2 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
GATA2 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
RUNX1 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TP53 |
MACROD2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00002CEB74 |
MACROD2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000011DF |
MACROD2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001CE046 |
MACROD2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000450F92 |
MACROD2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000544FF1 |
MACROD2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000078918 |
MACROD2 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000015A0D9 |
MACROD2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005CC20C |
MACROD2 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
TERF1 |
MACROD2 |
25348397
|
N/A |
physical interaction |
ComPPI |
TERF2 |
MACROD2 |
25348397
|
N/A |
physical interaction |
ComPPI |
EZR |
MACROD2 |
24234451
25348397
29568061
|
association |
pull down |
ComPPI,IntAct |
HSPA5 |
MACROD2 |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
Visualization