Gene Information gene info

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GENE：ASPH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ASPH
FullNmae aspartate beta-hydroxylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:757
EnsembleID ENSG00000198363
Uniprot Q12797

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ASPH immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ASPH GO:0005198,GO:0005509,GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0005789,GO:0005886,GO:0006936,GO:0007389,GO:0008283,GO:0008285,GO:0008307,GO:0009055,GO:0022900,GO:0031647,GO:0032541,GO:0033017,GO:0035108,GO:0042264,GO:0045862,GO:0060021,GO:0060325,GO:0062101,GO:0097202,GO:1901879

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ASPH hsa:444 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
ASPH hsa:444 path:hsa04260 Cardiac muscle contraction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GET3 ASPH 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR ASPH 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 ASPH 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ASPH 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A ASPH 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SP1 ASPH 17681019 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP3 ASPH 17681019 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ASPH 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ASPH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NOTCH3 ASPH 21504125 trascriptional regulation,stimulation inferred by curator TFlink
USF1 ASPH 19087304 trascriptional regulation,stimulation inferred by curator TFlink
USF2 ASPH 19087304 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 ASPH 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000F31F4 ASPH 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 ASPH 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00003AD2AA ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A611 ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024CEE0 ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000585553 ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BE495 ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000243FF1 ASPH 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GET3 ASPH 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CUL3 ASPH 25348397 N/A physical interaction ComPPI
NECTIN3 ASPH 25348397 N/A physical interaction ComPPI
HNRNPL ASPH 25348397 N/A physical interaction ComPPI
STXBP3 ASPH 25348397 N/A physical interaction ComPPI
SQSTM1 ASPH 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCHE ASPH 25348397 N/A physical interaction ComPPI
STX4 ASPH 25348397 N/A physical interaction ComPPI
TRDN ASPH 11069905 14525934 25348397 9287354 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
STX8 ASPH 25348397 N/A physical interaction ComPPI
HTT ASPH 17500595 24234451 25348397 physical association pull down ComPPI,IntAct
MAP1LC3A ASPH 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NOS2 ASPH 25348397 N/A physical interaction ComPPI
HTR2C ASPH 25348397 N/A physical interaction ComPPI
BNIP1 ASPH 25348397 N/A physical interaction ComPPI
TRIM25 ASPH 25348397 N/A physical interaction ComPPI
HLA-E ASPH 25348397 N/A physical interaction ComPPI
ECSIT ASPH 25348397 N/A physical interaction ComPPI
STEAP3 ASPH 25348397 N/A physical interaction ComPPI
NELL2 ASPH 25348397 N/A physical interaction ComPPI
IQCB1 ASPH 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VTI1B ASPH 25348397 N/A physical interaction ComPPI
ASPH APP 25348397 N/A physical interaction ComPPI
ASPH TARDBP 25348397 N/A physical interaction ComPPI
ASPH FBLN7 25348397 N/A physical interaction ComPPI
ASPH PTCH1 25348397 N/A physical interaction ComPPI
ASPH OLFM1 25348397 N/A physical interaction ComPPI
ASPH ATL3 25348397 N/A physical interaction ComPPI
ASPH TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ASPH MCUB 25348397 N/A physical interaction ComPPI
ASPH MCU 25348397 N/A physical interaction ComPPI
ASPH FAM162A 25348397 N/A physical interaction ComPPI
ASPH TMEM160 25348397 N/A physical interaction ComPPI
ASPH SMDT1 25348397 N/A physical interaction ComPPI
ASPH NDUFAF1 25348397 N/A physical interaction ComPPI
ASPH NTAQ1 25348397 N/A physical interaction ComPPI
ASPH LEMD2 25348397 N/A physical interaction ComPPI
ASPH LYZL2 25348397 N/A physical interaction ComPPI
ASPH TMEM192 25348397 N/A physical interaction ComPPI
ASPH CD93 25348397 N/A physical interaction ComPPI
ASPH LRRC59 25348397 N/A physical interaction ComPPI
ASPH SERPINA12 25348397 N/A physical interaction ComPPI
ASPH EXD2 25348397 N/A physical interaction ComPPI
ASPH ACAD9 25348397 N/A physical interaction ComPPI
ASPH SLC7A6OS 25348397 N/A physical interaction ComPPI
ASPH PDGFRL 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
HSCB ASPH 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
CHRM5 ASPH 24234451 28298427 physical association ubiquitin reconstruction IntAct
ASPH TRPC3 15302852 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B6B15 ASPH 27087310 direct interaction,inhibition N/A NPInter
URS00009BB2EB ASPH 27087310 direct interaction,inhibition N/A NPInter

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