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GENE：CHAF1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CHAF1B
FullNmae chromatin assembly factor 1 subunit B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1911
EnsembleID ENSG00000159259
Uniprot Q13112

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CHAF1B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CHAF1B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CHAF1B GO:0000785,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0006260,GO:0006281,GO:0006334,GO:0006334,GO:0006335,GO:0007049,GO:0032991,GO:0033186,GO:0033186,GO:0033186,GO:0042393,GO:0051082

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 CHAF1B 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 CHAF1B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 CHAF1B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CHAF1B 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CHAF1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 CHAF1B 20304954 20371350 23446348 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS0000338542 CHAF1B 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00005651EE CHAF1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000042935A CHAF1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B CHAF1B 20371350 23446348 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D CHAF1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 CHAF1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED CHAF1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D CHAF1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC CHAF1B 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001B968D CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1B CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 CHAF1B 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 CHAF1B 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 CHAF1B 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 CHAF1B 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC CHAF1B 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA CHAF1B 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F CHAF1B 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 CHAF1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 CHAF1B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 CHAF1B 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHAF1A CHAF1B 25361965 interaction type N/A PTMCode2
CHAF1B CHAF1A 25361965 interaction type N/A PTMCode2
CHAF1B PCNA 25361965 interaction type N/A PTMCode2
PCNA CHAF1B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PCNA CHAF1B 25348397 N/A physical interaction ComPPI
SMAD4 CHAF1B 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PFDN4 CHAF1B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
H4C1 CHAF1B 25348397 N/A physical interaction ComPPI
ASF1A CHAF1B 11897662 14525934 16980972 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
RPL10 CHAF1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBX1 CHAF1B 21888893 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
SETDB1 CHAF1B 25348397 N/A physical interaction ComPPI
JUN CHAF1B 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4G1 CHAF1B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CHAF1A CHAF1B 14525934 19498464 24234451 25348397 27705803 9614144 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation through density gradient,experimental interaction detection,physical interaction,in vivo,confocal microscopy,tandem affinity purification ComPPI,HPRD,IntAct
MYC CHAF1B 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
UHRF2 CHAF1B 25348397 N/A physical interaction ComPPI
NFATC2 CHAF1B 25348397 N/A physical interaction ComPPI
RBBP4 CHAF1B 14525934 24234451 25348397 27705803 9614144 association anti bait coimmunoprecipitation,experimental interaction detection,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SUMO2 CHAF1B 25348397 N/A physical interaction ComPPI
CDK2 CHAF1B 10938080 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SOX2 CHAF1B 25348397 N/A physical interaction ComPPI
CBX5 CHAF1B 19498464 20562864 24234451 25348397 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
H3-4 CHAF1B 25348397 N/A physical interaction ComPPI
BANF1 CHAF1B 25348397 N/A physical interaction ComPPI
H3C15 CHAF1B 25348397 N/A physical interaction ComPPI
TRIM28 CHAF1B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
H3C1 CHAF1B 14525934 15664198 17081972 19410544 19410545 19498464 20080577 24234451 25348397 26167883 29568061 association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
ASF1B CHAF1B 11897662 14525934 16980972 17353931 24234451 25348397 27705803 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
H3-3A CHAF1B 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
LRIF1 CHAF1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHAF1B APP 25348397 N/A physical interaction ComPPI
CHAF1B CNOT6L 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHAF1B CBX6 25348397 N/A physical interaction ComPPI
CHAF1B CBX3 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
CHAF1B OBSL1 25348397 N/A physical interaction ComPPI
CHAF1B CCDC8 25348397 N/A physical interaction ComPPI
CHAF1B INSL3 25348397 N/A physical interaction ComPPI
CHAF1B FBXW11 25348397 N/A physical interaction ComPPI
CHAF1B RBPJ 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CHAF1B TEAD2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
CHAF1B CEP72 25348397 N/A physical interaction ComPPI
CHAF1B NUDC 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CHAF1B PFDN2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
CHAF1B CDK1 10938080 14525934 N/A experimental interaction detection HPRD
PCNA CHAF1B 10648606 20112283 22939629 26344197 27898060 stimulant N/A OmniPath
ASF1A CHAF1B 11897662 16980972 27898060 stimulant N/A OmniPath
ASF1B CHAF1B 11897662 16980972 17353931 26527279 27898060 stimulant N/A OmniPath

Visualization










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