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GENE：ASAP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ASAP1
FullNmae ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2720
EnsembleID ENSG00000153317
Uniprot Q9ULH1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ASAP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ASAP1 GO:0000139,GO:0001786,GO:0002102,GO:0005096,GO:0005515,GO:0005546,GO:0005547,GO:0005829,GO:0032588,GO:0043197,GO:0045296,GO:0046872,GO:0060271,GO:0060271,GO:0061000,GO:0061512,GO:0098978,GO:0099175,GO:1903527

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ASAP1 hsa:50807 path:hsa04144 Endocytosis - Homo sapiens (human)
ASAP1 hsa:50807 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PLCG1 ASAP1 17474147 23180781 physical association anti tag coimmunoprecipitation,peptide array,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR ASAP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ASAP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ASAP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ASAP1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C ASAP1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ASAP1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 ASAP1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ASAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 ASAP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002FC5B0 ASAP1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000600E6 ASAP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004DA9DB ASAP1 24682952 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry TarBase
URS0000204177 ASAP1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 ASAP1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED ASAP1 24374217 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000034979B ASAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000330617 ASAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C83DA ASAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000308E4D ASAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C7662 ASAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PTK2B ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 PTK2B 25361965 interaction type N/A PTMCode2
ASAP1 SRC 25361965 interaction type N/A PTMCode2
SRC ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 CD2AP 25361965 interaction type N/A PTMCode2
CD2AP ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 SH3KBP1 25361965 interaction type N/A PTMCode2
SH3KBP1 ASAP1 25361965 interaction type N/A PTMCode2
PACSIN2 ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 PACSIN2 25361965 interaction type N/A PTMCode2
GRB2 ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 GRB2 25361965 interaction type N/A PTMCode2
CRK ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 CRK 25361965 interaction type N/A PTMCode2
PACSIN3 ASAP1 25361965 interaction type N/A PTMCode2
ASAP1 PACSIN3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 ASAP1 25348397 N/A physical interaction ComPPI
SH3KBP1 ASAP1 14525934 15090612 15719014 17255943 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,imaging technique,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PACSIN3 ASAP1 14525934 15719014 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CRK ASAP1 17474147 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
PACSIN1 ASAP1 25348397 N/A physical interaction ComPPI
CBL ASAP1 14525934 17255943 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TEC ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
PTK2B ASAP1 12771146 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
CBLB ASAP1 17255943 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PIK3R1 ASAP1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SRC ASAP1 14525934 16636290 17474147 24234451 25348397 9819391 physical association experimental interaction detection,peptide array,physical interaction,enzyme linked immunosorbent assay,in vitro,in vivo ComPPI,HPRD,IntAct
GRAP2 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
NCK1 ASAP1 16636290 17474147 24234451 25348397 physical association peptide array,enzyme linked immunosorbent assay ComPPI,IntAct
GRB2 ASAP1 17474147 19380743 20936779 21706016 21988832 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,peptide array,physical interaction,two hybrid pooling approach,tandem affinity purification ComPPI,IntAct
UBC ASAP1 17255943 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
NTRK1 ASAP1 25348397 N/A physical interaction ComPPI
APC ASAP1 20509626 24234451 25348397 27898060 N/A nuclear magnetic resonance ComPPI,IntAct,OmniPath
CDH1 ASAP1 25348397 N/A physical interaction ComPPI
PXN ASAP1 16636290 24234451 25348397 physical association pull down,physical interaction,in vitro ComPPI,IntAct
PTPN12 ASAP1 25348397 N/A physical interaction ComPPI
NPHP1 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
RAB11FIP1 ASAP1 25348397 N/A physical interaction ComPPI
REPS2 ASAP1 12149250 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
CBX4 ASAP1 25348397 N/A tandem affinity purification ComPPI
TRIP10 ASAP1 25348397 N/A physical interaction ComPPI
ARF6 ASAP1 25348397 N/A physical interaction ComPPI
DLG1 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
SNX9 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
PSTPIP1 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
CTTN ASAP1 16636290 17255943 24234451 25348397 association,physical association dynamic light scattering,molecular sieving,nuclear magnetic resonance,pull down,x-ray crystallography,physical interaction,competition binding ComPPI,IntAct
ASAP1 ARF1 14525934 16223492 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ASAP1 HCK 12029088 14525934 16636290 24234451 25348397 physical association experimental interaction detection,pull down,enzyme linked immunosorbent assay,in vivo ComPPI,HPRD,IntAct
ASAP1 PACSIN2 16636290 24234451 25348397 N/A physical interaction,enzyme linked immunosorbent assay ComPPI,IntAct
ASAP1 FCHSD1 25348397 N/A physical interaction ComPPI
ASAP1 ELAVL1 25348397 N/A physical interaction ComPPI
ASAP1 ARAP3 25348397 N/A physical interaction ComPPI
ASAP1 PTK2 25348397 N/A physical interaction ComPPI
ASAP1 LRRK1 25348397 N/A physical interaction ComPPI
ASAP1 RAB11FIP3 25348397 N/A physical interaction ComPPI
ASAP1 RAB11FIP2 25348397 N/A physical interaction ComPPI
ASAP1 ASAP3 25348397 N/A physical interaction ComPPI
ASAP1 TRIM25 25348397 N/A physical interaction ComPPI
ASAP1 PLCG1 17474147 24234451 25348397 physical association anti bait coimmunoprecipitation,fluorescence technology,peptide array ComPPI,IntAct
ASAP1 ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
ASAP1 FYN 16636290 17474147 24234451 25348397 physical association peptide array,enzyme linked immunosorbent assay ComPPI,IntAct
ASAP1 STAM 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
ASAP1 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ASAP1 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SH3GL2 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct

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