Gene Information gene info

  1. Home

GENE：CDT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDT1
FullNmae chromatin licensing and DNA replication factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24576
EnsembleID ENSG00000167513
Uniprot Q9H211

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDT1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDT1 GO:0000076,GO:0000076,GO:0000278,GO:0000776,GO:0003677,GO:0003677,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0016604,GO:0030174,GO:0030174,GO:0033262,GO:0035563,GO:0045740,GO:0045786,GO:0051301,GO:0051315,GO:0070182,GO:0071163,GO:0071163,GO:0072708,GO:1902595,GO:2000104,GO:2000105

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CDT1 hsa:81620 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDT1 CDC45 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 CDC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 MCM2 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 MCM3 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 MCM4 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 MCM5 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 MCM6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC1 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC2 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC3 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC4 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC5 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDT1 ORC6 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
MCM7 CDT1 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 26192618 7575488 interaction type N/A ACSN
CDK2 CDT1 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 26192618 7575488 interaction type N/A ACSN
CDC7 CDT1 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 26192618 7575488 interaction type N/A ACSN
DBF4 CDT1 15279786 17018296 17102137 17116885 17296725 17303408 17582221 17660363 18590585 19793801 26192618 7575488 interaction type N/A ACSN
RPA1 CDT1 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258 26192618 interaction type N/A ACSN
RPA2 CDT1 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258 26192618 interaction type N/A ACSN
RPA3 CDT1 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258 26192618 interaction type N/A ACSN
HUS1 CDT1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD1 CDT1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
RAD17 CDT1 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 26192618 8943031 9524127 interaction type N/A ACSN
CDK1 CDT1 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 26192618 7575488 interaction type N/A ACSN
ATRIP CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
ATR CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CHEK1 CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
CLSPN CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN
TIPIN CDT1 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 26192618 8943031 9524127 association N/A ACSN

Source Target Pmid Interactiontype Methods Database
E2F4 CDT1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 CDT1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CDT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CDT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CDT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CDT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 CDT1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 CDT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F CDT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000021D08 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000279B6F CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 CDT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 CDT1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 CDT1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F14FE CDT1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 CDT1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED CDT1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 CDT1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA CDT1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF CDT1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 CDT1 22135298 phosphorylation N/A PhosphoSite
MAPK8 CDT1 22135298 phosphorylation N/A PhosphoSite
MCM6 CDT1 25361965 interaction type N/A PTMCode2
CDT1 MCM6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 CDT1 25348397 N/A physical interaction ComPPI
ORC1 CDT1 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
CDC5L CDT1 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MAPK9 CDT1 25348397 N/A physical interaction ComPPI
CKS1B CDT1 25348397 N/A physical interaction ComPPI
NDC80 CDT1 22581055 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
GMNN CDT1 11125146 14525934 14993212 15232106 16482215 17318181 19906994 21543332 22581055 24234451 25348397 26496610 27107012 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer,molecular sieving,peptide array,protein array,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,x ray scattering,surface plasmon resonance array,validated two hybrid,barcode fusion genetics two hybrid ComPPI,HPRD,IntAct
NPM1 CDT1 25348397 N/A physical interaction ComPPI
PCNA CDT1 14525934 16407252 16482215 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
MCM6 CDT1 12192004 14525934 20202939 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MCM2 CDT1 25348397 N/A physical interaction ComPPI
ORC6 CDT1 22581055 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EP300 CDT1 25348397 N/A physical interaction ComPPI
TRIP4 CDT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS5 CDT1 25348397 N/A physical interaction ComPPI
MAPK14 CDT1 25348397 N/A physical interaction ComPPI
KAT2B CDT1 25348397 N/A physical interaction ComPPI
FZR1 CDT1 25348397 N/A physical interaction ComPPI
KPNB1 CDT1 25348397 N/A physical interaction ComPPI
FAF1 CDT1 25348397 N/A physical interaction ComPPI
CDC6 CDT1 14525934 14672932 15232106 24234451 25348397 physical association experimental interaction detection,protein array,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TP73 CDT1 25348397 N/A physical interaction ComPPI
XPO1 CDT1 25348397 N/A physical interaction ComPPI
ORC2 CDT1 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
CCNA1 CDT1 14993212 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4B CDT1 25348397 N/A physical interaction ComPPI
CDK2 CDT1 14525934 14993212 23455922 24234451 25348397 26496610 association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CUL1 CDT1 25348397 N/A physical interaction ComPPI
CUL4A CDT1 25348397 N/A physical interaction ComPPI
CDC20 CDT1 25348397 N/A physical interaction ComPPI
SKP2 CDT1 12840033 14525934 14993212 24234451 25348397 26496610 association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TFDP1 CDT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNB1 CDT1 25348397 N/A physical interaction ComPPI
TP63 CDT1 25348397 N/A physical interaction ComPPI
KAT7 CDT1 18832067 20980834 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BAZ1B CDT1 25348397 N/A physical interaction ComPPI
HDAC11 CDT1 19276081 20980834 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TIMM8A CDT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMM13 CDT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDB2 CDT1 25348397 N/A physical interaction ComPPI
DDB1 CDT1 15448697 22451935 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FOXO3 CDT1 25348397 N/A physical interaction ComPPI
CDK4 CDT1 25348397 N/A physical interaction ComPPI
CDT1 CCNA2 14525934 14993212 24234451 25348397 26496610 association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CDT1 CDC23 25348397 N/A physical interaction ComPPI
CDT1 ANAPC5 25348397 N/A physical interaction ComPPI
CDT1 SMARCA5 18162579 21937426 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CDT1 MCM4 25348397 N/A physical interaction ComPPI
CDT1 GRWD1 25348397 N/A physical interaction ComPPI
CDT1 TOP1 25348397 N/A physical interaction ComPPI
CDT1 ANAPC7 25348397 N/A physical interaction ComPPI
CDT1 TOP2A 25348397 N/A physical interaction ComPPI
CDT1 CCNE1 25348397 N/A physical interaction ComPPI
CDT1 CDK1 14525934 14993212 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
CDT1 DGCR8 25348397 N/A physical interaction ComPPI
CDT1 HECW2 25348397 N/A physical interaction ComPPI
CDT1 DTL 16861906 21930785 24906324 25348397 26272819 27898060 N/A physical interaction ComPPI,OmniPath
CDT1 FBXO31 25348397 N/A physical interaction ComPPI
CDT1 CDK3 25348397 N/A physical interaction ComPPI
CDT1 BZW1 25348397 N/A physical interaction ComPPI
CDT1 ANKHD1 25348397 N/A physical interaction ComPPI
CDT1 TRAPPC13 25348397 N/A physical interaction ComPPI
CDT1 SLAIN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDT1 USP37 25348397 N/A physical interaction ComPPI
CDT1 CKS2 25348397 N/A physical interaction ComPPI
CDT1 MCM7 25348397 N/A physical interaction ComPPI
CDT1 NUF2 22581055 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
CDT1 CDT1 14525934 14993212 N/A experimental interaction detection HPRD
CDT1 UBB 14525934 16407252 N/A experimental interaction detection HPRD
PCNA CDT1 16362051 16407242 16407252 16482215 16861906 18162579 19231300 21930785 24423875 26272819 27898060 inhibition,stimulant N/A OmniPath
CDK2 CDT1 14993212 15004027 15855168 23455922 26496610 27898060 N/A N/A OmniPath
MAPK14 CDT1 21930785 22820251 27898060 stimulant N/A OmniPath
E2F1 CDT1 14990995 18319725 19541929 27898060 stimulant N/A OmniPath
CDK1 CDT1 14993212 15855168 26186194 27898060 N/A N/A OmniPath
E2F4 CDT1 14990995 18319725 27898060 inhibition,stimulant N/A OmniPath
MAPK8 CDT1 18669648 21856198 27898060 N/A N/A OmniPath

Visualization










  Return