GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
CXCL6 |
FullNmae |
C-X-C motif chemokine ligand 6 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:10643 |
EnsembleID |
ENSG00000124875 |
Uniprot |
P80162 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
CXCL6 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
CXCL6 |
GO:0001776,GO:0005515,GO:0005576,GO:0005615,GO:0006935,GO:0006954,GO:0007165,GO:0007267,GO:0008009,GO:0008009,GO:0008201,GO:0030593,GO:0030593,GO:0032642,GO:0042119,GO:0042742,GO:0045236,GO:0061844,GO:0061844,GO:0070098,GO:0070951,GO:0071222,GO:0071222 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CXCL6 |
MMP1 |
18660381
23180781
|
protein cleavage |
protease assay |
InnateDB |
CXCL6 |
MMP9 |
18660381
23180781
|
protein cleavage |
protease assay |
InnateDB |
CXCL6 |
CXCR1 |
23180781
9485196
|
physical association |
competition binding |
InnateDB |
CXCL6 |
CXCR2 |
23180781
9485196
|
physical association |
competition binding |
InnateDB |
MMP12 |
CXCL6 |
18660381
23180781
|
protein cleavage |
protease assay |
InnateDB |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
CXCL6 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
GATA2 |
CXCL6 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
YBX1 |
CXCL6 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
CXCL6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
CXCL6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
CXCL6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
CXCL6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS000003ABC4 |
CXCL6 |
19088304
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS00000821E0 |
CXCL6 |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CXCL6 |
CXCR1 |
25361965
|
interaction type |
N/A |
PTMCode2 |
CXCR1 |
CXCL6 |
25361965
|
interaction type |
N/A |
PTMCode2 |
CXCL6 |
MMP9 |
25361965
|
interaction type |
N/A |
PTMCode2 |
MMP9 |
CXCL6 |
25361965
|
interaction type |
N/A |
PTMCode2 |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PF4 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding,surface plasmon resonance,surface plasmon resonance array |
ComPPI,IntAct |
CCL5 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding,surface plasmon resonance,surface plasmon resonance array |
ComPPI,IntAct |
CXCR2 |
CXCL6 |
10593335
14525934
25348397
9692902
|
N/A |
experimental interaction detection,in vivo |
ComPPI,HPRD |
CCL8 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
CXCL12 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding,surface plasmon resonance,surface plasmon resonance array |
ComPPI,IntAct |
SSX2IP |
CXCL6 |
24234451
24397932
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
CCL11 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
CXCL1 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
MMP9 |
CXCL6 |
25348397
|
N/A |
physical interaction |
ComPPI |
PPBP |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
CCL7 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
CXCR1 |
CXCL6 |
10593335
14525934
25348397
9692902
|
N/A |
experimental interaction detection,in vivo |
ComPPI,HPRD |
CXCL10 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
CXCL6 |
CXCL3 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
CXCL2 |
CXCL6 |
24234451
25348397
28381538
|
N/A |
filter binding |
ComPPI,IntAct |
MMP9 |
CXCL6 |
18660381
27898060
|
N/A |
N/A |
OmniPath |
MMP1 |
CXCL6 |
18660381
27898060
|
N/A |
N/A |
OmniPath |
CXCL6 |
CXCR2 |
10593335
24218476
27898060
9485196
9692902
|
stimulant |
N/A |
OmniPath |
CXCL6 |
CXCR1 |
10593335
12964882
24218476
27898060
9485196
9692902
|
stimulant |
N/A |
OmniPath |
Visualization