GENE:FXR1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | FXR1 |
FullNmae | FMR1 autosomal homolog 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:4023 |
EnsembleID | ENSG00000114416 |
Uniprot | P51114 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
FXR1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
FXR1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
FXR1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
FXR1 | GO:0000381,GO:0001934,GO:0003723,GO:0003723,GO:0003730,GO:0003730,GO:0005515,GO:0005634,GO:0005635,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005844,GO:0006915,GO:0007286,GO:0007517,GO:0010494,GO:0014069,GO:0016020,GO:0016020,GO:0017148,GO:0021542,GO:0030424,GO:0030426,GO:0032720,GO:0033592,GO:0035925,GO:0036464,GO:0036464,GO:0042803,GO:0042803,GO:0043025,GO:0043034,GO:0043197,GO:0043232,GO:0043488,GO:0044326,GO:0045182,GO:0045187,GO:0045727,GO:0045727,GO:0046982,GO:0048471,GO:0050728,GO:0050767,GO:0051292,GO:0051489,GO:0051664,GO:0051966,GO:0060538,GO:0061157,GO:0098793,GO:0098978,GO:0140693,GO:0140694,GO:1900272,GO:1902737,GO:2000637 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NOS2 | FXR1 | 19864602 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SUZ12 | FXR1 | 23180781 24457600 | physical association | anti tag coimmunoprecipitation | InnateDB |
FXR1 | ELAVL1 | 19322201 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | FXR1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
E2F4 | FXR1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | FXR1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
MYC | FXR1 | 12747840 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | FXR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | FXR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | FXR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | FXR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | FXR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000EED18 | FXR1 | 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS0000065D58 | FXR1 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS00001C770D | FXR1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000006FDD4 | FXR1 | 22473208 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001AFC71 | FXR1 | 20371350 23446348 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000028BB8 | FXR1 | 20371350 23446348 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00000821E0 | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001F0C23 | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002FC5B0 | FXR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000021D08 | FXR1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A7F58 | FXR1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040828B | FXR1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EE123 | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5BAA | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003808EC | FXR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000202460 | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003ACE11 | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002C02E4 | FXR1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B59A2 | FXR1 | 23708386 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003D8730 | FXR1 | 23708386 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000306C70 | FXR1 | 23708386 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000004203C | FXR1 | 23708386 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002E1509 | FXR1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000AB32B | FXR1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000284586 | FXR1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000315338 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002C0FCB | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002ECEE4 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00003BBF48 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000521626 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000016C318 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000000C73C | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000042E1F | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000060B2B | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001C11BC | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000251D0B | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000031602A | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000195F5B | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00004BC299 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000043D2C1 | FXR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PAK1 | FXR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
CYFIP1 | FXR1 | 25361965 | interaction type | N/A | PTMCode2 |
FXR1 | CYFIP1 | 25361965 | interaction type | N/A | PTMCode2 |
FXR1 | FMR1 | 25361965 | interaction type | N/A | PTMCode2 |
FMR1 | FXR1 | 25361965 | interaction type | N/A | PTMCode2 |
FXR1 | CYFIP2 | 25361965 | interaction type | N/A | PTMCode2 |
CYFIP2 | FXR1 | 25361965 | interaction type | N/A | PTMCode2 |
FXR2 | FXR1 | 25361965 | interaction type | N/A | PTMCode2 |
FXR1 | FXR2 | 25361965 | interaction type | N/A | PTMCode2 |
DICER1 | FXR1 | 25361965 | interaction type | N/A | PTMCode2 |
FXR1 | DICER1 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TSNAX | FXR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FXR2 | FXR1 | 14525934 25348397 7489725 8668200 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
MAGEA4 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
SKP1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
BMI1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
NFATC1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
PRKCD | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
JUN | FXR1 | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
COPS5 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
EIF4G1 | FXR1 | 23974796 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
GLI1 | FXR1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
GSK3B | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
RBX1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
CUL3 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
CLU | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
NTRK1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
CSNK2A1 | FXR1 | 22113938 24234451 25348397 | phosphorylation reaction | physical interaction,protein kinase assay | ComPPI,IntAct |
HABP4 | FXR1 | 21771594 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
RANBP9 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
UBA6 | FXR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ORC2 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
THOC1 | FXR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TOP3B | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
CUL1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
PINX1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
HSPB1 | FXR1 | 24234451 25277244 25348397 | physical association | reverse ras recruitment system,physical interaction | ComPPI,IntAct |
CCNB1 | FXR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CRMP1 | FXR1 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
CEP126 | FXR1 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
CUL7 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
HDAC5 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
CAND1 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
BCLAF1 | FXR1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FXR1 | FMR1 | 10527928 14525934 24778252 25348397 26186194 27898060 7489725 8668200 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
FXR1 | CYFIP2 | 11438699 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
FXR1 | ERG28 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
FXR1 | PRSS23 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
FXR1 | LUC7L2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
FXR1 | LRIF1 | 14525934 16169070 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
FXR1 | GBP2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
FXR1 | CYFIP1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | GIGYF2 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | TDRD3 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | CAPRIN1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | LRWD1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | UBAP2 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | CCDC8 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | SUZ12 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | WDR76 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | LUC7L | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | IFI16 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | CCNA2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FXR1 | CDK18 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FXR1 | SNCA | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | NOP56 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | CCDC93 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | THOC2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FXR1 | SLAIN2 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | MYH7B | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | TUBA1C | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | FOXQ1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FXR1 | FOXS1 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
FXR1 | LGALS3BP | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | RRP8 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | PLEKHO1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | ZNF512 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | G3BP1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | FBXO4 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | CLEC14A | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | CEP63 | 24234451 25348397 26297806 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
FXR1 | RIF1 | 16169070 24234451 25348397 | physical association | two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
FXR1 | AGO2 | 17932509 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
FXR1 | SF3B3 | 23974796 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
FXR1 | PLEKHA7 | 24234451 25348397 28877994 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
PLK2 | FXR1 | 25348397 | N/A | physical interaction | ComPPI |
FXR1 | FXR1 | 14525934 21446998 24234451 7489725 | N/A | electron microscopy,experimental interaction detection | HPRD,IntAct |
DICER1 | FXR1 | 21858095 24234451 | association | anti tag coimmunoprecipitation | IntAct |
INAVA | FXR1 | 24234451 29420262 | association | anti tag coimmunoprecipitation | IntAct |
H1-2 | FXR1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
H1-5 | FXR1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
L1TD1 | FXR1 | 24234451 25702638 | association | anti bait coimmunoprecipitation | IntAct |
PAK1 | FXR1 | 20417602 27898060 | N/A | N/A | OmniPath |