Gene Information gene info

GENE:FXR1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FXR1
FullNmae FMR1 autosomal homolog 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4023
EnsembleID ENSG00000114416
Uniprot P51114

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FXR1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FXR1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FXR1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FXR1 GO:0000381,GO:0001934,GO:0003723,GO:0003723,GO:0003730,GO:0003730,GO:0005515,GO:0005634,GO:0005635,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005844,GO:0006915,GO:0007286,GO:0007517,GO:0010494,GO:0014069,GO:0016020,GO:0016020,GO:0017148,GO:0021542,GO:0030424,GO:0030426,GO:0032720,GO:0033592,GO:0035925,GO:0036464,GO:0036464,GO:0042803,GO:0042803,GO:0043025,GO:0043034,GO:0043197,GO:0043232,GO:0043488,GO:0044326,GO:0045182,GO:0045187,GO:0045727,GO:0045727,GO:0046982,GO:0048471,GO:0050728,GO:0050767,GO:0051292,GO:0051489,GO:0051664,GO:0051966,GO:0060538,GO:0061157,GO:0098793,GO:0098978,GO:0140693,GO:0140694,GO:1900272,GO:1902737,GO:2000637

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NOS2 FXR1 19864602 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 FXR1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
FXR1 ELAVL1 19322201 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FXR1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 FXR1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FXR1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC FXR1 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FXR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FXR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FXR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FXR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FXR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 FXR1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 FXR1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001C770D FXR1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000006FDD4 FXR1 22473208 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001AFC71 FXR1 20371350 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000028BB8 FXR1 20371350 23446348 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000821E0 FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 FXR1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 FXR1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 FXR1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B FXR1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC FXR1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 FXR1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 FXR1 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 FXR1 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 FXR1 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C FXR1 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 FXR1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B FXR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 FXR1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C0FCB FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003BBF48 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000521626 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000016C318 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000C73C FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000042E1F FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000060B2B FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C11BC FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000251D0B FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000031602A FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000195F5B FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004BC299 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000043D2C1 FXR1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PAK1 FXR1 22135298 phosphorylation N/A PhosphoSite
CYFIP1 FXR1 25361965 interaction type N/A PTMCode2
FXR1 CYFIP1 25361965 interaction type N/A PTMCode2
FXR1 FMR1 25361965 interaction type N/A PTMCode2
FMR1 FXR1 25361965 interaction type N/A PTMCode2
FXR1 CYFIP2 25361965 interaction type N/A PTMCode2
CYFIP2 FXR1 25361965 interaction type N/A PTMCode2
FXR2 FXR1 25361965 interaction type N/A PTMCode2
FXR1 FXR2 25361965 interaction type N/A PTMCode2
DICER1 FXR1 25361965 interaction type N/A PTMCode2
FXR1 DICER1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TSNAX FXR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR2 FXR1 14525934 25348397 7489725 8668200 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAGEA4 FXR1 25348397 N/A physical interaction ComPPI
SKP1 FXR1 25348397 N/A physical interaction ComPPI
BMI1 FXR1 25348397 N/A physical interaction ComPPI
NFATC1 FXR1 25348397 N/A physical interaction ComPPI
PRKCD FXR1 25348397 N/A physical interaction ComPPI
JUN FXR1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 FXR1 25348397 N/A physical interaction ComPPI
EIF4G1 FXR1 23974796 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
GLI1 FXR1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GSK3B FXR1 25348397 N/A physical interaction ComPPI
RBX1 FXR1 25348397 N/A physical interaction ComPPI
CUL3 FXR1 25348397 N/A physical interaction ComPPI
CLU FXR1 25348397 N/A physical interaction ComPPI
NTRK1 FXR1 25348397 N/A physical interaction ComPPI
CSNK2A1 FXR1 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
HABP4 FXR1 21771594 24234451 25348397 physical association two hybrid ComPPI,IntAct
RANBP9 FXR1 25348397 N/A physical interaction ComPPI
UBA6 FXR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ORC2 FXR1 25348397 N/A physical interaction ComPPI
THOC1 FXR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOP3B FXR1 25348397 N/A physical interaction ComPPI
CUL1 FXR1 25348397 N/A physical interaction ComPPI
PINX1 FXR1 25348397 N/A physical interaction ComPPI
HSPB1 FXR1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
CCNB1 FXR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRMP1 FXR1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CEP126 FXR1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CUL7 FXR1 25348397 N/A physical interaction ComPPI
HDAC5 FXR1 25348397 N/A physical interaction ComPPI
CAND1 FXR1 25348397 N/A physical interaction ComPPI
BCLAF1 FXR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR1 FMR1 10527928 14525934 24778252 25348397 26186194 27898060 7489725 8668200 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FXR1 CYFIP2 11438699 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
FXR1 ERG28 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FXR1 PRSS23 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FXR1 LUC7L2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FXR1 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FXR1 GBP2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FXR1 CYFIP1 25348397 N/A physical interaction ComPPI
FXR1 GIGYF2 25348397 N/A physical interaction ComPPI
FXR1 ELAVL1 25348397 N/A physical interaction ComPPI
FXR1 SIRT7 25348397 N/A physical interaction ComPPI
FXR1 TDRD3 25348397 N/A physical interaction ComPPI
FXR1 CAPRIN1 25348397 N/A physical interaction ComPPI
FXR1 LRWD1 25348397 N/A physical interaction ComPPI
FXR1 UBAP2 25348397 N/A physical interaction ComPPI
FXR1 CCDC8 25348397 N/A physical interaction ComPPI
FXR1 SUZ12 25348397 N/A physical interaction ComPPI
FXR1 WDR76 25348397 N/A physical interaction ComPPI
FXR1 LUC7L 25348397 N/A physical interaction ComPPI
FXR1 IFI16 25348397 N/A physical interaction ComPPI
FXR1 CCNA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR1 CDK18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR1 SNCA 25348397 N/A physical interaction ComPPI
FXR1 NOP56 25348397 N/A physical interaction ComPPI
FXR1 CCDC93 25348397 N/A physical interaction ComPPI
FXR1 THOC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR1 SLAIN2 25348397 N/A physical interaction ComPPI
FXR1 MYH7B 25348397 N/A physical interaction ComPPI
FXR1 TUBA1C 25348397 N/A physical interaction ComPPI
FXR1 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FXR1 FOXS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FXR1 LGALS3BP 25348397 N/A physical interaction ComPPI
FXR1 RRP8 25348397 N/A physical interaction ComPPI
FXR1 PLEKHO1 25348397 N/A physical interaction ComPPI
FXR1 ZNF512 25348397 N/A physical interaction ComPPI
FXR1 G3BP1 25348397 N/A physical interaction ComPPI
FXR1 FBXO4 25348397 N/A physical interaction ComPPI
FXR1 CLEC14A 25348397 N/A physical interaction ComPPI
FXR1 CEP63 24234451 25348397 26297806 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FXR1 AGO2 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FXR1 SF3B3 23974796 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
FXR1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
PLK2 FXR1 25348397 N/A physical interaction ComPPI
FXR1 FXR1 14525934 21446998 24234451 7489725 N/A electron microscopy,experimental interaction detection HPRD,IntAct
DICER1 FXR1 21858095 24234451 association anti tag coimmunoprecipitation IntAct
INAVA FXR1 24234451 29420262 association anti tag coimmunoprecipitation IntAct
H1-2 FXR1 24234451 30021884 physical association cross-linking study IntAct
H1-5 FXR1 24234451 30021884 physical association cross-linking study IntAct
L1TD1 FXR1 24234451 25702638 association anti bait coimmunoprecipitation IntAct
PAK1 FXR1 20417602 27898060 N/A N/A OmniPath

Visualization