Gene Information gene info

GENE:NIPBL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NIPBL
FullNmae NIPBL cohesin loading factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28862
EnsembleID ENSG00000164190
Uniprot Q6KC79

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NIPBL mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NIPBL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NIPBL autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NIPBL GO:0000070,GO:0000122,GO:0000785,GO:0001656,GO:0003007,GO:0003007,GO:0003151,GO:0003682,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006974,GO:0007064,GO:0007064,GO:0007420,GO:0007420,GO:0007605,GO:0008104,GO:0032039,GO:0032116,GO:0034087,GO:0034088,GO:0035019,GO:0035115,GO:0035136,GO:0035261,GO:0036033,GO:0040018,GO:0042471,GO:0042634,GO:0042826,GO:0043231,GO:0045444,GO:0045778,GO:0045944,GO:0045995,GO:0048557,GO:0048565,GO:0048589,GO:0048592,GO:0048638,GO:0048703,GO:0050890,GO:0060325,GO:0061010,GO:0061038,GO:0061775,GO:0061780,GO:0070062,GO:0070087,GO:0071169,GO:0071481,GO:0090694,GO:0090694,GO:1990414,GO:1990841,GO:2001224

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NIPBL hsa:25836 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EED NIPBL 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NIPBL 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NIPBL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NIPBL 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NIPBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000055128B NIPBL 19826008 25416803 mrna cleavage,inhibition array technology,rna immunoprecipitation,quantitative reverse transcription pcr TarBase
URS00004505E4 NIPBL 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000009262D NIPBL 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 NIPBL 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000035CC3E NIPBL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002152A8 NIPBL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB NIPBL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000204177 NIPBL 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD NIPBL 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000058DCD8 NIPBL 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 NIPBL 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 NIPBL 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 NIPBL 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L NIPBL 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK6 NIPBL 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
RAD21 NIPBL 25348397 N/A physical interaction ComPPI
RPL10 NIPBL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SF3A2 NIPBL 25348397 N/A physical interaction ComPPI
RPA1 NIPBL 25348397 N/A physical interaction ComPPI
KSR2 NIPBL 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
EWSR1 NIPBL 25348397 N/A physical interaction ComPPI
RPA2 NIPBL 25348397 N/A physical interaction ComPPI
RPA3 NIPBL 25348397 N/A physical interaction ComPPI
SP100 NIPBL 25348397 N/A physical interaction ComPPI
SMC1A NIPBL 25348397 N/A physical interaction ComPPI
CBX5 NIPBL 20562864 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
MED23 NIPBL 25348397 N/A physical interaction ComPPI
SMC3 NIPBL 25348397 N/A physical interaction ComPPI
EED NIPBL 25348397 N/A physical interaction ComPPI
CDK8 NIPBL 25348397 N/A physical interaction ComPPI
TRIM25 NIPBL 25348397 N/A physical interaction ComPPI
TFG NIPBL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARFGAP1 NIPBL 25348397 N/A physical interaction ComPPI
BRCA1 NIPBL 25348397 N/A physical interaction ComPPI
HINFP NIPBL 25348397 N/A physical interaction ComPPI
LDHD NIPBL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM40 NIPBL 25348397 N/A physical interaction ComPPI
PRSS23 NIPBL 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MLLT3 NIPBL 25348397 N/A physical interaction ComPPI
USP37 NIPBL 25348397 N/A physical interaction ComPPI
DBN1 NIPBL 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NIPBL CBX3 25348397 N/A physical interaction ComPPI
NIPBL SIRT7 25348397 N/A physical interaction ComPPI
NIPBL PPT1 25348397 N/A physical interaction ComPPI
NIPBL MAU2 16802858 21934712 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
NIPBL OBSL1 25348397 N/A physical interaction ComPPI
NIPBL CCDC8 25348397 N/A physical interaction ComPPI
NIPBL SUCO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MKI67 NIPBL 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization