GENE:NIPBL
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | NIPBL |
FullNmae | NIPBL cohesin loading factor |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:28862 |
EnsembleID | ENSG00000164190 |
Uniprot | Q6KC79 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
NIPBL | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
NIPBL | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
NIPBL | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
NIPBL | GO:0000070,GO:0000122,GO:0000785,GO:0001656,GO:0003007,GO:0003007,GO:0003151,GO:0003682,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006974,GO:0007064,GO:0007064,GO:0007420,GO:0007420,GO:0007605,GO:0008104,GO:0032039,GO:0032116,GO:0034087,GO:0034088,GO:0035019,GO:0035115,GO:0035136,GO:0035261,GO:0036033,GO:0040018,GO:0042471,GO:0042634,GO:0042826,GO:0043231,GO:0045444,GO:0045778,GO:0045944,GO:0045995,GO:0048557,GO:0048565,GO:0048589,GO:0048592,GO:0048638,GO:0048703,GO:0050890,GO:0060325,GO:0061010,GO:0061038,GO:0061775,GO:0061780,GO:0070062,GO:0070087,GO:0071169,GO:0071481,GO:0090694,GO:0090694,GO:1990414,GO:1990841,GO:2001224 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
NIPBL | hsa:25836 | path:hsa04110 | Cell cycle - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | NIPBL | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | NIPBL | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | NIPBL | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | NIPBL | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000055128B | NIPBL | 19826008 25416803 | mrna cleavage,inhibition | array technology,rna immunoprecipitation,quantitative reverse transcription pcr | TarBase |
URS00004505E4 | NIPBL | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS000009262D | NIPBL | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000324096 | NIPBL | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS000035CC3E | NIPBL | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00002152A8 | NIPBL | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000345DEB | NIPBL | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000204177 | NIPBL | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002A71AD | NIPBL | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000058DCD8 | NIPBL | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000031E12 | NIPBL | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000259AE4 | NIPBL | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SNW1 | NIPBL | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDC5L | NIPBL | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDK6 | NIPBL | 22094256 24234451 25348397 | phosphorylation reaction | physical interaction,protein kinase assay | ComPPI,IntAct |
RAD21 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
RPL10 | NIPBL | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SF3A2 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
RPA1 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
KSR2 | NIPBL | 24234451 25348397 27086506 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
EWSR1 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
RPA2 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
RPA3 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
SP100 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
SMC1A | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
CBX5 | NIPBL | 20562864 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
MED23 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
SMC3 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
EED | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
CDK8 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
TRIM25 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
TFG | NIPBL | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ARFGAP1 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
BRCA1 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
HINFP | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
LDHD | NIPBL | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TOMM40 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
PRSS23 | NIPBL | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
MLLT3 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
USP37 | NIPBL | 25348397 | N/A | physical interaction | ComPPI |
DBN1 | NIPBL | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
NIPBL | CBX3 | 25348397 | N/A | physical interaction | ComPPI |
NIPBL | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
NIPBL | PPT1 | 25348397 | N/A | physical interaction | ComPPI |
NIPBL | MAU2 | 16802858 21934712 24234451 25348397 26496610 | association,physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
NIPBL | OBSL1 | 25348397 | N/A | physical interaction | ComPPI |
NIPBL | CCDC8 | 25348397 | N/A | physical interaction | ComPPI |
NIPBL | SUCO | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MKI67 | NIPBL | 24234451 26949251 | association | anti tag coimmunoprecipitation | IntAct |