GENE:BCL11B
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | BCL11B |
FullNmae | BCL11 transcription factor B |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:13222 |
EnsembleID | ENSG00000127152 |
Uniprot | Q9C0K0 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
BCL11B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
BCL11B | GO:0000978,GO:0001228,GO:0003334,GO:0003382,GO:0003700,GO:0005515,GO:0005634,GO:0006366,GO:0008285,GO:0010837,GO:0016514,GO:0019216,GO:0021773,GO:0021902,GO:0031077,GO:0033077,GO:0033153,GO:0035701,GO:0042475,GO:0043005,GO:0043368,GO:0045664,GO:0045944,GO:0045944,GO:0046632,GO:0046872,GO:0048538,GO:0070242,GO:0070244,GO:0071678,GO:0097535,GO:1990837 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
BCL11B | hsa:64919 | path:hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
BCL11B | CHD3 | 16091750 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
BCL11B | MTA2 | 16091750 23180781 | physical association | anti tag coimmunoprecipitation,gst pull down | InnateDB |
BCL11B | MTA1 | 16091750 23180781 | physical association | anti tag coimmunoprecipitation,gst pull down | InnateDB |
BCL11B | HDAC2 | 16091750 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
BCL11B | HDAC1 | 16091750 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
MBD3 | BCL11B | 16091750 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | BCL11B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
TFAP2C | BCL11B | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | BCL11B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | BCL11B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000021D7C8 | BCL11B | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS0000345DEB | BCL11B | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
URS00002FC5B0 | BCL11B | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
URS000003ABC4 | BCL11B | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00004DA9DB | BCL11B | 23807165 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00001E3523 | BCL11B | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000018E6CD | BCL11B | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00005CCD18 | BCL11B | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000486E0B | BCL11B | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000007A060 | BCL11B | 22291592 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000A939F | BCL11B | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000435A77 | BCL11B | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000004203C | BCL11B | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A7F58 | BCL11B | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C85B2 | BCL11B | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B989F | BCL11B | 20371350 21572407 23446348 24398324 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000411752 | BCL11B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000E7139 | BCL11B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000BA274 | BCL11B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004B4B85 | BCL11B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000016FD1A | BCL11B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001CE046 | BCL11B | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PRKCA | BCL11B | 22135298 | phosphorylation | N/A | PhosphoSite |
MTA1 | BCL11B | 25361965 | interaction type | N/A | PTMCode2 |
BCL11B | MTA1 | 25361965 | interaction type | N/A | PTMCode2 |
CHD4 | BCL11B | 25361965 | interaction type | N/A | PTMCode2 |
BCL11B | CHD4 | 25361965 | interaction type | N/A | PTMCode2 |
NR2F2 | BCL11B | 25361965 | interaction type | N/A | PTMCode2 |
BCL11B | NR2F2 | 25361965 | interaction type | N/A | PTMCode2 |
BCL11B | RBBP4 | 25361965 | interaction type | N/A | PTMCode2 |
RBBP4 | BCL11B | 25361965 | interaction type | N/A | PTMCode2 |
BCL11B | SUV39H1 | 25361965 | interaction type | N/A | PTMCode2 |
SUV39H1 | BCL11B | 25361965 | interaction type | N/A | PTMCode2 |
BCL11B | RBBP7 | 25361965 | interaction type | N/A | PTMCode2 |
RBBP7 | BCL11B | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AIM2 | BCL11B | 24234451 25348397 25665578 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
SP1 | BCL11B | 25348397 | N/A | physical interaction | ComPPI |
NOTCH1 | BCL11B | 23022380 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
NFATC1 | BCL11B | 25348397 | N/A | physical interaction | ComPPI |
HDAC3 | BCL11B | 17245431 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
NFATC2 | BCL11B | 25348397 | N/A | physical interaction | ComPPI |
NR2F2 | BCL11B | 10744719 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
BCL11B | SUV39H1 | 14525934 17245431 24234451 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo | ComPPI,HPRD,IntAct |
BCL11B | NR2F1 | 10744719 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
BCL11B | CHD4 | 25348397 | N/A | physical interaction | ComPPI |
BCL11B | MTA2 | 25348397 | N/A | physical interaction | ComPPI |
BCL11B | MTA1 | 25348397 | N/A | physical interaction | ComPPI |
BCL11B | RBBP7 | 25348397 | N/A | physical interaction | ComPPI |
BCL11B | RBBP4 | 25348397 | N/A | physical interaction | ComPPI |
BCL11B | HDAC2 | 17245431 23752268 24234451 25348397 | colocalization,association,physical association | anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy | ComPPI,IntAct |
BCL11B | HDAC1 | 17245431 23752268 24234451 25348397 | colocalization,association,physical association | anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy | ComPPI,IntAct |
BCL11B | MBD3 | 25348397 | N/A | physical interaction | ComPPI |
BCL11B | HDAC6 | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
BCL11B | TAL1 | 19497860 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CBX5 | BCL11B | 12692243 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |