Gene Information gene info

GENE:BCL11B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BCL11B
FullNmae BCL11 transcription factor B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13222
EnsembleID ENSG00000127152
Uniprot Q9C0K0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BCL11B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BCL11B GO:0000978,GO:0001228,GO:0003334,GO:0003382,GO:0003700,GO:0005515,GO:0005634,GO:0006366,GO:0008285,GO:0010837,GO:0016514,GO:0019216,GO:0021773,GO:0021902,GO:0031077,GO:0033077,GO:0033153,GO:0035701,GO:0042475,GO:0043005,GO:0043368,GO:0045664,GO:0045944,GO:0045944,GO:0046632,GO:0046872,GO:0048538,GO:0070242,GO:0070244,GO:0071678,GO:0097535,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BCL11B hsa:64919 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BCL11B CHD3 16091750 23180781 physical association anti tag coimmunoprecipitation InnateDB
BCL11B MTA2 16091750 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
BCL11B MTA1 16091750 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
BCL11B HDAC2 16091750 23180781 physical association anti tag coimmunoprecipitation InnateDB
BCL11B HDAC1 16091750 23180781 physical association anti tag coimmunoprecipitation InnateDB
MBD3 BCL11B 16091750 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 BCL11B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C BCL11B 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 BCL11B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BCL11B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 BCL11B 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000345DEB BCL11B 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002FC5B0 BCL11B 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000003ABC4 BCL11B 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00004DA9DB BCL11B 23807165 25416803 mrna cleavage,inhibition array technology TarBase
URS00001E3523 BCL11B 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000018E6CD BCL11B 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 BCL11B 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B BCL11B 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 BCL11B 22291592 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000A939F BCL11B 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 BCL11B 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C BCL11B 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 BCL11B 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 BCL11B 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F BCL11B 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 BCL11B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 BCL11B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 BCL11B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 BCL11B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A BCL11B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 BCL11B 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCA BCL11B 22135298 phosphorylation N/A PhosphoSite
MTA1 BCL11B 25361965 interaction type N/A PTMCode2
BCL11B MTA1 25361965 interaction type N/A PTMCode2
CHD4 BCL11B 25361965 interaction type N/A PTMCode2
BCL11B CHD4 25361965 interaction type N/A PTMCode2
NR2F2 BCL11B 25361965 interaction type N/A PTMCode2
BCL11B NR2F2 25361965 interaction type N/A PTMCode2
BCL11B RBBP4 25361965 interaction type N/A PTMCode2
RBBP4 BCL11B 25361965 interaction type N/A PTMCode2
BCL11B SUV39H1 25361965 interaction type N/A PTMCode2
SUV39H1 BCL11B 25361965 interaction type N/A PTMCode2
BCL11B RBBP7 25361965 interaction type N/A PTMCode2
RBBP7 BCL11B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
AIM2 BCL11B 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
SP1 BCL11B 25348397 N/A physical interaction ComPPI
NOTCH1 BCL11B 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NFATC1 BCL11B 25348397 N/A physical interaction ComPPI
HDAC3 BCL11B 17245431 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NFATC2 BCL11B 25348397 N/A physical interaction ComPPI
NR2F2 BCL11B 10744719 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
BCL11B SUV39H1 14525934 17245431 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,HPRD,IntAct
BCL11B NR2F1 10744719 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
BCL11B CHD4 25348397 N/A physical interaction ComPPI
BCL11B MTA2 25348397 N/A physical interaction ComPPI
BCL11B MTA1 25348397 N/A physical interaction ComPPI
BCL11B RBBP7 25348397 N/A physical interaction ComPPI
BCL11B RBBP4 25348397 N/A physical interaction ComPPI
BCL11B HDAC2 17245431 23752268 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
BCL11B HDAC1 17245431 23752268 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
BCL11B MBD3 25348397 N/A physical interaction ComPPI
BCL11B HDAC6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL11B TAL1 19497860 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBX5 BCL11B 12692243 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath

Visualization