GENE:DOCK5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DOCK5 |
| FullNmae | dedicator of cytokinesis 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23476 |
| EnsembleID | ENSG00000147459 |
| Uniprot | Q9H7D0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DOCK5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DOCK5 | GO:0002102,GO:0005085,GO:0005085,GO:0005096,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0005886,GO:0007520,GO:0010634,GO:0016477,GO:0016601,GO:0031267,GO:0042995,GO:0046849,GO:0070161,GO:0071800,GO:1900026,GO:1904694,GO:1904754 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DOCK5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | DOCK5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | DOCK5 | N/A | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS000009262D | DOCK5 | 22158624 | rna interference,inhibition | experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS0000324096 | DOCK5 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| URS000009262D | DOCK5 | 22158624 25416803 | mrna cleavage,inhibition | experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000122ED0 | DOCK5 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000070B1D | DOCK5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000DDD35 | DOCK5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000153377 | DOCK5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000284586 | DOCK5 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDC5L | DOCK5 | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HSPA8 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R1A | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ATXN1 | DOCK5 | 23275563 24234451 25348397 | physical association | physical interaction,two hybrid prey pooling approach | ComPPI,IntAct |
| CRKL | DOCK5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GRB2 | DOCK5 | 21706016 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PIK3CB | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| TUBA4A | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2CA | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ELMO1 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| ELMO2 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| RNASEL | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| TCP1 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CCT5 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CCT7 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ZHX2 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| HDAC6 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| MYCBP2 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| PJA1 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R1B | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| BRIP1 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| TGOLN2 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| PRKD2 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| TUBB1 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| DSP | DOCK5 | 25348397 | N/A | anti tag coimmunoprecipitation | ComPPI |
| STIL | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| TUBB3 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| CCT4 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CCT2 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CCT6A | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CDCA5 | DOCK5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PLEKHG4 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| NOL11 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| CCT8 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CCT3 | DOCK5 | 19156129 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| PPP4R3A | DOCK5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TRIM65 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| AHI1 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| SMG8 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| DOCK5 | WDR19 | 25348397 | N/A | physical interaction | ComPPI |
