GENE：P2RX1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | P2RX1 |
| FullNmae | purinergic receptor P2X 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8533 |
| EnsembleID | ENSG00000108405 |
| Uniprot | P51575 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| P2RX1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| P2RX1 | GO:0001614,GO:0002554,GO:0003056,GO:0004931,GO:0005261,GO:0005515,GO:0005524,GO:0005886,GO:0005886,GO:0006811,GO:0006915,GO:0007165,GO:0007320,GO:0008217,GO:0009897,GO:0019228,GO:0030168,GO:0030667,GO:0032991,GO:0033198,GO:0035249,GO:0035579,GO:0035590,GO:0042802,GO:0043924,GO:0044877,GO:0045211,GO:0046513,GO:0048787,GO:0060079,GO:0070588,GO:0098978,GO:0099509,GO:1905665,GO:2000300 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| P2RX1 | hsa:5023 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
| P2RX1 | hsa:5023 | path:hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| P2RX1 | hsa:5023 | path:hsa04611 | Platelet activation - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | P2RX1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | P2RX1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | P2RX1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | P2RX1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | P2RX1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | P2RX1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | P2RX1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GMCL1 | P2RX1 | 25348397 | N/A | physical interaction | ComPPI |
| P2RX1 | GMCL2 | 25348397 | N/A | physical interaction | ComPPI |
| P2RX1 | GOLPH3L | 25348397 | N/A | physical interaction | ComPPI |
| P2RX1 | OMA1 | 25348397 | N/A | physical interaction | ComPPI |
| P2RX1 | SGPL1 | 25348397 | N/A | physical interaction | ComPPI |
| P2RX1 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| GOLPH3 | P2RX1 | 25348397 | N/A | physical interaction | ComPPI |
| HSPD1 | P2RX1 | 24234451 30021884 | physical association | cross-linking study | IntAct |