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GENE：VAMP7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol VAMP7
FullNmae vesicle associated membrane protein 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11486
EnsembleID ENSG00000124333
Uniprot P51809

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
VAMP7 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
VAMP7 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
VAMP7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
VAMP7 GO:0000149,GO:0005484,GO:0005515,GO:0005737,GO:0005765,GO:0005765,GO:0005765,GO:0005789,GO:0005802,GO:0005886,GO:0005886,GO:0006887,GO:0006888,GO:0006906,GO:0006906,GO:0006911,GO:0008333,GO:0008333,GO:0015031,GO:0016020,GO:0016192,GO:0017156,GO:0030027,GO:0030141,GO:0030658,GO:0030667,GO:0030669,GO:0030670,GO:0031091,GO:0031143,GO:0031201,GO:0031201,GO:0031201,GO:0031902,GO:0035577,GO:0043005,GO:0043231,GO:0043308,GO:0043308,GO:0043312,GO:0043312,GO:0043320,GO:0045202,GO:0045335,GO:0070062,GO:1903595

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
VAMP7 hsa:6845 path:hsa04130 SNARE interactions in vesicular transport - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ZNF143 VAMP7 14672948 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR1I2 VAMP7 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP1 VAMP7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 VAMP7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 VAMP7 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000DDD35 VAMP7 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SRC VAMP7 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNAP29 VAMP7 12853575 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
STX12 VAMP7 25348397 N/A physical interaction ComPPI
PPP2R1A VAMP7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
AP3M1 VAMP7 25348397 N/A physical interaction ComPPI
SNAP25 VAMP7 12853575 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SNAP23 VAMP7 14525934 24234451 25348397 26359495 9614185 physical association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
ANKRD27 VAMP7 19745841 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
STX4 VAMP7 14525934 14993220 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
STX1A VAMP7 12853575 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VAMP7 STX7 11278762 12175335 14525934 19557002 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
VAMP7 AP3D1 12853575 14525934 18775314 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
VAMP7 STX3 14525934 25348397 9614185 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
VAMP7 DNAJC5 14525934 15610015 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
VAMP7 AGFG1 14525934 18775314 24234451 25348397 physical association two hybrid,experimental interaction detection,isothermal titration calorimetry,pull down,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
VAMP7 ATP6V1B1 25348397 N/A physical interaction ComPPI
VAMP7 STX6 19557002 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VAMP7 GINM1 25348397 N/A physical interaction ComPPI
VAMP7 SIRT2 25348397 N/A physical interaction ComPPI
VAMP7 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VAMP7 RAB11A 25348397 N/A physical interaction ComPPI
VAMP7 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VAMP7 ATP6V1A 21674799 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
VAMP7 SNAP47 24234451 25348397 26359495 physical association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
VAMP7 BET1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VAMP7 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STX8 VAMP7 19557002 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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