Gene Information gene info

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GENE：CBL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CBL
FullNmae Cbl proto-oncogene
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1541
EnsembleID ENSG00000110395
Uniprot P22681

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CBL lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
CBL lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
CBL immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CBL GO:0001784,GO:0004842,GO:0005509,GO:0005515,GO:0005794,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005925,GO:0005929,GO:0006511,GO:0006974,GO:0007165,GO:0007175,GO:0008584,GO:0010332,GO:0014823,GO:0016567,GO:0016567,GO:0016567,GO:0016567,GO:0016600,GO:0017124,GO:0017124,GO:0019221,GO:0030426,GO:0030971,GO:0032487,GO:0033574,GO:0035635,GO:0036120,GO:0036312,GO:0042059,GO:0042059,GO:0042594,GO:0043066,GO:0043303,GO:0045121,GO:0045296,GO:0045471,GO:0045742,GO:0046875,GO:0048260,GO:0048471,GO:0051897,GO:0061630,GO:0061630,GO:0070086,GO:0090650,GO:1990090,GO:2000583

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CBL hsa:867 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
CBL hsa:867 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
CBL hsa:867 path:hsa04144 Endocytosis - Homo sapiens (human)
CBL hsa:867 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
CBL hsa:867 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
CBL hsa:867 path:hsa05200 Pathways in cancer - Homo sapiens (human)
CBL hsa:867 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
CBL hsa:867 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BCAR1 CBL 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 26192618 interaction type N/A ACSN
CBL RAPGEF1 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 26192618 interaction type N/A ACSN
CRK CBL 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 26192618 interaction type N/A ACSN
CRKL CBL 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 26192618 7682895 9314552 interaction type N/A ACSN
CBL CD247 11353765 15169881 18835194 20189481 26192618 interaction type N/A ACSN
CBL ZAP70 10358158 11133830 11353765 15169881 15268851 18835194 20189481 23109003 26192618 interaction type,inhibition N/A ACSN,SignaLink
CBL VAV1 11353765 15169881 18835194 20189481 26192618 interaction type N/A ACSN
GRB2 CBL 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26192618 26552706 8551221 interaction type N/A ACSN
CD48 CBL 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
SH2D1A CBL 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
SH2D1B CBL 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 26192618 7890616 9535722 interaction type N/A ACSN
SLAMF7 CBL 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 26192618 7890616 9535722 interaction type N/A ACSN
CBL RAP1A 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 26192618 interaction type N/A ACSN
ABL1 CBL 10837221 15459660 18835194 21051857 21199784 21435002 26192618 interaction type N/A ACSN
CBL GAB1 10514377 17635922 26192618 interaction type N/A ACSN
CBL GRB2 10514377 17635922 26192618 interaction type N/A ACSN
TRAF6 CBL 11406619 23180781 physical association anti tag coimmunoprecipitation InnateDB
CBL CD40 12637493 23180781 physical association anti tag coimmunoprecipitation InnateDB
CBL SYK 10617633 11331248 23180781 physical association anti tag coimmunoprecipitation InnateDB
VAV1 CBL 11331248 23180781 23331499 9200440 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
AXL CBL 15958209 23180781 physical association anti tag coimmunoprecipitation InnateDB
CD33 CBL 18062779 23180781 physical association pull down InnateDB
EGR1 CBL 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
CBL LYN 12244174 23180781 9160881 physical association two hybrid,affinity technology InnateDB
CBL EGFR 10086340 10428778 10514377 12061819 12593795 12604776 12734385 14505571 14627991 15107835 15159412 15210722 15282549 15668240 15962011 16105874 16246327 16969069 17242169 17486068 17545148 17971399 17995934 18273061 18316398 18508924 19225046 19531499 19713535 20940296 21071413 21772844 23331499 stimulation N/A SignaLink,SignaLink
LRIG1 CBL 15282549 23331499 stimulation N/A SignaLink,SignaLink
CBL PDGFRA 18988627 23331499 9234717 stimulation N/A SignaLink,SignaLink
LTK CBL 23331499 9223670 stimulation N/A SignaLink,SignaLink
CBL MET 11894096 15123609 16397241 18273061 19450681 23331499 stimulation N/A SignaLink
CBL ABL1 11494134 12475393 20675402 23331499 stimulation N/A SignaLink
FRS2 CBL 11997436 23331499 stimulation N/A SignaLink
SH2B2 CBL 10374881 15737992 23331499 stimulation N/A SignaLink
CBL LCK 11904433 23109003 inhibition N/A SignaLink
ZAP70 CBL 10779765 11133830 23109003 8798643 chemical activation reaction N/A SignaLink
CBL PLCG1 11709089 12941616 23109003 inhibition N/A SignaLink
CBL PIK3R1 15790353 16107703 17722974 22315502 23109003 8080844 inhibition N/A SignaLink
PTEN CBL 23109003 23118026 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ABI1 CBL 17395426 20005715 20542890 interaction type,stimulation N/A PSP,SignaLink
CD19 CBL 20005715 interaction type N/A PSP,SignaLink
CD2AP CBL 11067845 12618476 15128873 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
CRK CBL 20005715 interaction type N/A PSP,SignaLink
FRS2 CBL 20005715 interaction type N/A PSP,SignaLink
FYB1 CBL 20005715 interaction type N/A PSP,SignaLink
GRB2 CBL 10086340 10204582 10570290 11133830 11823423 11964172 11997436 14725908 15210722 16906159 169092 18273061 18988627 19278030 20005715 20542890 21071413 8063801 8621483 8995445 9108316 9174058 917890 9234717 9295052 9367879 9461587 98621719 interaction type,stimulation N/A PSP,SignaLink
KRT18 CBL 20005715 interaction type N/A PSP
LAT CBL 20005715 interaction type N/A PSP,SignaLink
LAT2 CBL 20005715 interaction type N/A PSP,SignaLink
LCP2 CBL 10204582 10477741 18988627 20005715 21071413 9716598 interaction type N/A PSP,SignaLink
NCK1 CBL 10204582 18988627 20005715 21071413 7517397 interaction type N/A PSP,SignaLink
PIK3R1 CBL 11087752 11994282 15107835 20005715 21071413 21203488 9461587 9918857 interaction type N/A PSP,SignaLink
PXN CBL 20005715 interaction type N/A PSP
SH2B2 CBL 20005715 interaction type N/A PSP,SignaLink
SH3BP2 CBL 20005715 interaction type N/A PSP,SignaLink
SH3GL2 CBL 20005715 interaction type N/A PSP,SignaLink
SHC1 CBL 20005715 interaction type N/A PSP
SLA2 CBL 11891219 12024036 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
SORBS1 CBL 11001060 12504111 15128873 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
SPRY2 CBL 20005715 interaction type N/A PSP
SPRY4 CBL 20005715 interaction type N/A PSP
YWHAB CBL 20005715 interaction type N/A PSP
YWHAG CBL 20005715 interaction type N/A PSP
YWHAQ CBL 20005715 interaction type N/A PSP
YWHAZ CBL 20005715 interaction type N/A PSP
NEDD4 CBL 12907674 20542890 inhibition N/A SignaLink
SH3KBP1 CBL 11071869 11152963 11894095 11894095 11894095 11894096 12135478 12177062 12177062 12618476 15107835 15456872 16407834 18988627 20542890 21071413 stimulation N/A SignaLink
SH3GLB1 CBL 11894095 20542890 stimulation N/A SignaLink
UBASH3A CBL 15107835 15107835 15159412 15159412 20542890 21071413 inhibition N/A SignaLink
CBL EGFR 15194809 20542890 stimulation N/A SignaLink
YWHAB CBL 20005715 21071413 9367879 N/A N/A SignaLink
YWHAQ CBL 20005715 21071413 8663231 N/A N/A SignaLink
YWHAZ CBL 20005715 21071413 9367879 N/A N/A SignaLink
UBASH3B CBL 15159412 15159412 18988627 20542890 inhibition N/A SignaLink
SHC1 CBL 10570290 18988627 20005715 21071413 8621719 8662998 9234717 9461587 N/A N/A SignaLink
KRT18 CBL 20005715 N/A N/A SignaLink
PXN CBL 20005715 21071413 22203672 8641358 N/A N/A SignaLink
SPRY4 CBL 18273061 20005715 21071413 N/A N/A SignaLink
YWHAG CBL 15324660 18988627 20005715 N/A N/A SignaLink
SPRY2 CBL 11053437 11983899 12234920 12593795 12593796 16246327 16893902 18273061 18988627 20005715 20877636 21071413 21596750 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 CBL 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CBL 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CBL 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CBL 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CBL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA CBL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 CBL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FD1A CBL 23604034 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 CBL 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 CBL 23434382 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS0000083D87 CBL 23434382 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS0000435A77 CBL 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 CBL 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 CBL 25416803 26206089 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000383DF4 CBL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000475586 CBL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 CBL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC CBL 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SYK CBL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SRC CBL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK CBL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
FYN CBL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LYN CBL 22135298 phosphorylation N/A PhosphoSite
PIK3CA CBL 25361965 interaction type N/A PTMCode2
CBL PIK3CA 25361965 interaction type N/A PTMCode2
KDR CBL 25361965 interaction type N/A PTMCode2
CBL KDR 25361965 interaction type N/A PTMCode2
CSK CBL 25361965 interaction type N/A PTMCode2
CBL CSK 25361965 interaction type N/A PTMCode2
CBL TYK2 25361965 interaction type N/A PTMCode2
TYK2 CBL 25361965 interaction type N/A PTMCode2
CBL ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CBL 25361965 interaction type N/A PTMCode2
CBL IGF1R 25361965 interaction type N/A PTMCode2
IGF1R CBL 25361965 interaction type N/A PTMCode2
CBL LRIG1 25361965 interaction type N/A PTMCode2
LRIG1 CBL 25361965 interaction type N/A PTMCode2
CBL PIK3R1 25361965 interaction type N/A PTMCode2
PIK3R1 CBL 25361965 interaction type N/A PTMCode2
CBL EGFR 25361965 interaction type N/A PTMCode2
EGFR CBL 25361965 interaction type N/A PTMCode2
CBL NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 CBL 25361965 interaction type N/A PTMCode2
CBL FLT1 25361965 interaction type N/A PTMCode2
FLT1 CBL 25361965 interaction type N/A PTMCode2
CBL UBASH3B 25361965 interaction type N/A PTMCode2
UBASH3B CBL 25361965 interaction type N/A PTMCode2
CBL SORBS2 25361965 interaction type N/A PTMCode2
SORBS2 CBL 25361965 interaction type N/A PTMCode2
CBL CSF1R 25361965 interaction type N/A PTMCode2
CSF1R CBL 25361965 interaction type N/A PTMCode2
CBL KIT 25361965 interaction type N/A PTMCode2
KIT CBL 25361965 interaction type N/A PTMCode2
CBL NCK1 25361965 interaction type N/A PTMCode2
NCK1 CBL 25361965 interaction type N/A PTMCode2
CBL STAT5A 25361965 interaction type N/A PTMCode2
STAT5A CBL 25361965 interaction type N/A PTMCode2
CBL MST1R 25361965 interaction type N/A PTMCode2
MST1R CBL 25361965 interaction type N/A PTMCode2
CBL F2RL1 25361965 interaction type N/A PTMCode2
F2RL1 CBL 25361965 interaction type N/A PTMCode2
CBL INPPL1 25361965 interaction type N/A PTMCode2
INPPL1 CBL 25361965 interaction type N/A PTMCode2
CBL FRS2 25361965 interaction type N/A PTMCode2
FRS2 CBL 25361965 interaction type N/A PTMCode2
CBL YWHAB 25361965 interaction type N/A PTMCode2
YWHAB CBL 25361965 interaction type N/A PTMCode2
CBL CRK 25361965 interaction type N/A PTMCode2
CRK CBL 25361965 interaction type N/A PTMCode2
CBL BCR 25361965 interaction type N/A PTMCode2
BCR CBL 25361965 interaction type N/A PTMCode2
CBL INSR 25361965 interaction type N/A PTMCode2
INSR CBL 25361965 interaction type N/A PTMCode2
CBL BTK 25361965 interaction type N/A PTMCode2
BTK CBL 25361965 interaction type N/A PTMCode2
CBL KHDRBS1 25361965 interaction type N/A PTMCode2
KHDRBS1 CBL 25361965 interaction type N/A PTMCode2
CBL TRAF6 25361965 interaction type N/A PTMCode2
TRAF6 CBL 25361965 interaction type N/A PTMCode2
CBL MET 25361965 interaction type N/A PTMCode2
MET CBL 25361965 interaction type N/A PTMCode2
CBL UBASH3A 25361965 interaction type N/A PTMCode2
UBASH3A CBL 25361965 interaction type N/A PTMCode2
CBL CSF1 25361965 interaction type N/A PTMCode2
CSF1 CBL 25361965 interaction type N/A PTMCode2
CBL PTK2B 25361965 interaction type N/A PTMCode2
PTK2B CBL 25361965 interaction type N/A PTMCode2
CBL LCK 25361965 interaction type N/A PTMCode2
CBL GRB2 25361965 interaction type N/A PTMCode2
GRB2 CBL 25361965 interaction type N/A PTMCode2
CBL ERBB4 25361965 interaction type N/A PTMCode2
ERBB4 CBL 25361965 interaction type N/A PTMCode2
CBL CD5 25361965 interaction type N/A PTMCode2
CD5 CBL 25361965 interaction type N/A PTMCode2
CBL SPRY1 25361965 interaction type N/A PTMCode2
SPRY1 CBL 25361965 interaction type N/A PTMCode2
CBL UBE2L3 25361965 interaction type N/A PTMCode2
UBE2L3 CBL 25361965 interaction type N/A PTMCode2
CBL SPRY4 25361965 interaction type N/A PTMCode2
SPRY4 CBL 25361965 interaction type N/A PTMCode2
CBL CRKL 25361965 interaction type N/A PTMCode2
CRKL CBL 25361965 interaction type N/A PTMCode2
CBL RET 25361965 interaction type N/A PTMCode2
RET CBL 25361965 interaction type N/A PTMCode2
CBL SRC 25361965 interaction type N/A PTMCode2
CBL EPHA2 25361965 interaction type N/A PTMCode2
EPHA2 CBL 25361965 interaction type N/A PTMCode2
CBL CD2AP 25361965 interaction type N/A PTMCode2
CD2AP CBL 25361965 interaction type N/A PTMCode2
CBL SPTA1 25361965 interaction type N/A PTMCode2
SPTA1 CBL 25361965 interaction type N/A PTMCode2
CBL FYN 25361965 interaction type N/A PTMCode2
CBL VAV2 25361965 interaction type N/A PTMCode2
VAV2 CBL 25361965 interaction type N/A PTMCode2
CBL CD40 25361965 interaction type N/A PTMCode2
CD40 CBL 25361965 interaction type N/A PTMCode2
CBL ABL1 25361965 interaction type N/A PTMCode2
ABL1 CBL 25361965 interaction type N/A PTMCode2
CBL FGR 25361965 interaction type N/A PTMCode2
FGR CBL 25361965 interaction type N/A PTMCode2
CBL ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 CBL 25361965 interaction type N/A PTMCode2
CBL SYK 25361965 interaction type N/A PTMCode2
CBL HCK 25361965 interaction type N/A PTMCode2
HCK CBL 25361965 interaction type N/A PTMCode2
CBL SPRY2 25361965 interaction type N/A PTMCode2
SPRY2 CBL 25361965 interaction type N/A PTMCode2
CBL EPHB6 25361965 interaction type N/A PTMCode2
EPHB6 CBL 25361965 interaction type N/A PTMCode2
CBL GAPVD1 25361965 interaction type N/A PTMCode2
GAPVD1 CBL 25361965 interaction type N/A PTMCode2
CBL SH3KBP1 25361965 interaction type N/A PTMCode2
SH3KBP1 CBL 25361965 interaction type N/A PTMCode2
CBL SH3GL3 25361965 interaction type N/A PTMCode2
SH3GL3 CBL 25361965 interaction type N/A PTMCode2
CBL PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CBL 25361965 interaction type N/A PTMCode2
CBL SLA 25361965 interaction type N/A PTMCode2
SLA CBL 25361965 interaction type N/A PTMCode2
CBL SHC1 25361965 interaction type N/A PTMCode2
SHC1 CBL 25361965 interaction type N/A PTMCode2
LCP2 CBL 25361965 interaction type N/A PTMCode2
CBL LCP2 25361965 interaction type N/A PTMCode2
EPOR CBL 25361965 interaction type N/A PTMCode2
CBL EPOR 25361965 interaction type N/A PTMCode2
TRIM21 CBL 25361965 interaction type N/A PTMCode2
CBL TRIM21 25361965 interaction type N/A PTMCode2
YWHAQ CBL 25361965 interaction type N/A PTMCode2
CBL YWHAQ 25361965 interaction type N/A PTMCode2
PDGFRA CBL 25361965 interaction type N/A PTMCode2
CBL PDGFRA 25361965 interaction type N/A PTMCode2
BLK CBL 25361965 interaction type N/A PTMCode2
CBL BLK 25361965 interaction type N/A PTMCode2
PIK3R2 CBL 25361965 interaction type N/A PTMCode2
CBL PIK3R2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 CBL 25348397 N/A physical interaction ComPPI
PIK3R2 CBL 14525934 19380743 24234451 25348397 25814554 7629144 association,physical association experimental interaction detection,physical interaction,two hybrid array,in vivo,tandem affinity purification,validated two hybrid ComPPI,HPRD,IntAct
KRT6A CBL 25348397 N/A physical interaction ComPPI
KRT6B CBL 25348397 N/A physical interaction ComPPI
KRT18 CBL 14525934 25348397 9367879 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
KRT6C CBL 25348397 N/A physical interaction ComPPI
LCP2 CBL 10204582 14525934 24234451 25348397 9716598 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RAB39B CBL 25348397 N/A physical interaction ComPPI
TRIM21 CBL 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FRS3 CBL 25348397 N/A physical interaction ComPPI
YES1 CBL 25348397 N/A physical interaction ComPPI
HSPA8 CBL 25348397 N/A physical interaction ComPPI
CDC42 CBL 25348397 N/A physical interaction ComPPI
SPRY2 CBL 11053437 12234920 12815057 14525934 15962011 16893902 18273061 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SPRY1 CBL 16893902 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBASH3A CBL 15107835 15159412 16429130 17709377 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBASH3B CBL 14525934 15159412 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SH3KBP1 CBL 10679202 11894095 12177062 12618476 14525934 14596919 15090612 15962011 16407834 19268472 20711168 24234451 25036637 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SGTA CBL 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
LAT CBL 14525934 25348397 8798643 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SORBS3 CBL 25348397 N/A physical interaction ComPPI
KRT5 CBL 25348397 N/A physical interaction ComPPI
KRT2 CBL 25348397 N/A physical interaction ComPPI
KRT79 CBL 25348397 N/A physical interaction ComPPI
VIM CBL 25348397 N/A physical interaction ComPPI
WAS CBL 25348397 N/A physical interaction ComPPI
TUBB CBL 15878338 19380743 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TRAF6 CBL 11406619 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ACTB CBL 25348397 N/A physical interaction ComPPI
TYK2 CBL 14525934 25348397 8780698 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
YWHAG CBL 11697890 14525934 15324660 24234451 25348397 association experimental interaction detection,biochemical,in vivo ComPPI,HPRD,IntAct
CALM1 CBL 25348397 N/A physical interaction ComPPI
UBE2D1 CBL 25348397 N/A physical interaction ComPPI
PTPN6 CBL 12176909 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAP1LC3B CBL 22138575 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
CRK CBL 14525934 15581361 19380743 24234451 25348397 25814554 8524328 8621483 8626543 8662998 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,validated two hybrid ComPPI,HPRD,IntAct
APPL1 CBL 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
ERBB2 CBL 24234451 25081058 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ERBIN CBL 25348397 N/A physical interaction ComPPI
CBL VAV1 11133830 14525934 24234451 25348397 9200440 association experimental interaction detection,pull down,physical interaction,genetic,in vitro,in vivo ComPPI,HPRD,IntAct
CBL LYN 12149655 14525934 24234451 25348397 8621719 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
CBL ZAP70 10074432 11133830 14525934 22266821 24234451 25348397 8798643 physical association experimental interaction detection,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
CBL ITK 14525934 25348397 8810341 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBL SRC 14525934 16636290 17094785 17141222 18273061 24234451 25348397 8635998 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,pull down,physical interaction,competition binding,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
CBL NOTCH1 11777909 14525934 25348397 26052821 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
CBL BTK 10427990 14525934 25348397 7629518 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CBL SYK 10540342 11133830 14525934 15556646 18273061 24234451 25348397 8621719 9857068 phosphorylation reaction,physical association coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CBL SCN5A 14525934 25348397 8621719 N/A experimental interaction detection,in vivo ComPPI,HPRD
CBL VAV2 11313921 14525934 15345594 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
CBL NCK1 14525934 24234451 25348397 7517397 physical association coimmunoprecipitation,experimental interaction detection,phage display,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CBL SHC1 10570290 14525934 15677445 19380743 24234451 25348397 8621719 8662998 9234717 association,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CBL INPPL1 12504111 14525934 19380743 24234451 25348397 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CBL SLA 10449770 14525934 16327786 17237826 18193084 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CBL PTK2B 11149930 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL UBE2G1 11032556 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBL CRKL 12244174 14525934 15556646 16982329 24234451 25348397 25814554 8621483 8626543 8662998 8978305 9162067 9590251 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,far western blotting,pull down,physical interaction,two hybrid array,in vitro,in vivo ComPPI,HPRD,IntAct
CBL KHDRBS1 14525934 24234451 25348397 9045636 physical association coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
CBL EPHB6 25348397 N/A in vivo ComPPI
CBL UBE2D2 10514377 14525934 22266821 24234451 25348397 physical association experimental interaction detection,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
CBL UBE2G2 11032556 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBL UBE2L3 10531381 10966114 11278816 12234920 14525934 15062086 16735510 24234451 25348397 27898060 N/A experimental interaction detection,x-ray crystallography,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
CBL CD2AP 11067845 12559036 12618476 12672817 12874286 14525934 15128873 17020880 17072306 17188587 22706086 24234451 25036637 25348397 25872741 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
CBL SORBS1 11001060 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CBL SLA2 11891219 12024036 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBL PTPN22 10068674 14525934 25348397 N/A anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBL FRS2 11997436 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CBL CDKL2 14525934 25348397 7721825 N/A experimental interaction detection,in vivo ComPPI,HPRD
CBL GRB2 11133830 11964172 14525934 14725908 15677445 16906159 169092 17094785 18273061 19380743 20936779 21706016 23799367 24234451 25036637 25348397 25814554 7642581 8063801 8621483 8995445 9108316 917890 9234717 9295052 98621719 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,two hybrid pooling approach,competition binding,in vitro,in vivo,tandem affinity purification,luminescence based mammalian interactome mapping ComPPI,HPRD,IntAct
CBL PDGFRB 10514377 14525934 17620338 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
CBL YWHAB 11157475 11697890 14525934 24234451 24255178 25348397 9367879 association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro,two hybrid ComPPI,HPRD,IntAct
CBL YWHAZ 11697890 14525934 20618440 24234451 25348397 9367879 association two hybrid,physical interaction,biochemical,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
CBL PRKCA 11024037 14525934 24234451 25348397 25814554 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro ComPPI,HPRD,IntAct
CBL EPHA2 12496371 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL PTPN11 11157475 14525934 17330819 18519587 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
CBL FYB1 14525934 16503409 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL KDR 12649282 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CBL AXL 14525934 15958209 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL CD40 12637493 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CBL CAPN1 14525934 25348397 8695851 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBL EPOR 11443118 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL KIT 14525934 25348397 8950973 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL STAT5A 12193575 14525934 23533197 24234451 25348397 25814554 27898060 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,validated two hybrid ComPPI,HPRD,IntAct,OmniPath
CBL TNFRSF11A 11406619 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CBL STAT5B 12193575 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CBL LAT2 25348397 N/A in vitro,in vivo ComPPI
CBL SH2B2 10374881 11997497 14525934 15031295 15737992 18273061 24234451 25348397 9233773 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CBL ITCH 12226085 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CBL SORBS2 12475393 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CBL PIK3R1 11133830 14525934 15556646 15581361 16219545 16982329 19380743 24234451 25348397 7642581 8621719 8662998 9160881 9234717 9890970 association,physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,far western blotting,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CBL F2RL1 14525934 15708858 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,in vivo,confocal microscopy ComPPI,HPRD,IntAct,OmniPath
CBL ASAP1 14525934 17255943 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CBL PDGFRA 14525934 25348397 9234717 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBL FNBP1 14525934 18273061 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CBL EGFR 10092522 10799548 11239464 11994282 14525934 15657067 15677445 15962011 16729043 16914641 18273061 20308550 20562913 23799367 24234451 25348397 27059931 7657591 8662998 8798643 9890970 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,far western blotting,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,HPRD,IntAct
CBL FYN 10092522 10799548 11239464 11994282 14525934 15556646 17094785 24234451 25348397 7642581 8621719 9535867 9890970 phosphorylation reaction,physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,competition binding,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CBL HCK 10092522 10799548 11239464 11994282 14525934 25348397 9890970 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBL INSR 10635327 11997497 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBL LTK 14525934 25348397 9223670 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBL CD5 14525934 23376399 25348397 27898060 9603468 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CBL LCK 11741956 11904433 14525934 16107303 24234451 25348397 7721825 8621719 9178909 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
CBL CD19 14525934 25348397 9178909 N/A experimental interaction detection,in vivo ComPPI,HPRD
CBL RET 12727845 14525934 15677445 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
CBL CSF1R 11847211 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
CBL MET 11894096 14525934 18273061 21163258 24234451 25241761 25348397 ubiquitination reaction,physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,mass spectrometry studies of complexes,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct
CBL MYO1C 25348397 N/A physical interaction ComPPI
CBL ARHGEF7 16407834 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CBL SH3BP2 25348397 N/A physical interaction ComPPI
CBL SH3GL3 25348397 N/A physical interaction ComPPI
CBL FGR 12435267 14525934 25348397 7721825 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CBL ABL1 12475393 14525934 15556646 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
CBL PLCG1 12061819 14525934 16467851 24234451 25241761 25348397 9234717 9712732 physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
CBL FLOT1 25348397 N/A physical interaction ComPPI
CBL CSK 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CBL SPRY4 18273061 24234451 25348397 physical association anti tag coimmunoprecipitation,isothermal titration calorimetry,x-ray crystallography,physical interaction ComPPI,IntAct
CBL UBC 14661060 15117950 15273720 17679095 18596201 23851457 25348397 26548852 27898060 N/A physical interaction ComPPI,OmniPath
CBL CSF1 25348397 N/A physical interaction ComPPI
CBL GAPVD1 25348397 N/A physical interaction ComPPI
CBL ITSN1 16914641 17875942 18539136 18654987 21712076 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,far western blotting,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
CBL MST1R 12802274 16740632 18273061 24234451 25348397 27898060 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct,OmniPath
CBL UBE2M 25348397 N/A physical interaction ComPPI
CBL ITGA5 25348397 N/A physical interaction ComPPI
CBL LRIG1 25348397 N/A physical interaction ComPPI
CBL GAPDH 25348397 N/A physical interaction ComPPI
CBL EEF1A1 25348397 N/A physical interaction ComPPI
CBL EEF1A1P5 25348397 N/A physical interaction ComPPI
CBL CD247 25348397 N/A physical interaction ComPPI
CBL STAP2 17675501 19401194 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CBL TNFRSF10A 25348397 N/A physical interaction ComPPI
CBL TNFRSF10B 25348397 N/A physical interaction ComPPI
CBL FCGR2A 25348397 N/A physical interaction ComPPI
CBL MYH9 25348397 N/A physical interaction ComPPI
CBL ACTA1 25348397 N/A physical interaction ComPPI
CBL ACTG2 25348397 N/A physical interaction ComPPI
CBL HSPA4 25348397 N/A physical interaction ComPPI
CBL HSPA5 25348397 N/A physical interaction ComPPI
CBL EPHA8 25348397 N/A physical interaction ComPPI
CBL UBE4B 25348397 N/A physical interaction ComPPI
CBL EPHB1 25348397 N/A physical interaction ComPPI
CBL IL7R 25348397 N/A physical interaction ComPPI
CBL CD33 25348397 N/A physical interaction ComPPI
CBL NTRK1 21570973 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL CFTR 20525683 22467879 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CBL PSMC5 25348397 N/A physical interaction ComPPI
CBL TEK 25348397 N/A physical interaction ComPPI
CBL BAG1 25348397 N/A physical interaction ComPPI
CBL PTK2 25348397 N/A physical interaction ComPPI
CBL PXN 25348397 N/A physical interaction ComPPI
CBL IRF8 25348397 N/A physical interaction ComPPI
CBL IRS1 25348397 N/A physical interaction ComPPI
CBL ITSN2 25348397 N/A physical interaction ComPPI
CBL HRAS 25348397 N/A physical interaction ComPPI
CBL DBNL 25348397 N/A physical interaction ComPPI
CBL TNFRSF1A 25348397 N/A physical interaction ComPPI
CBL MAPK14 25348397 N/A physical interaction ComPPI
CBL MAPK8 16982329 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL BLNK 10684856 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CBL INPP5D 16601135 25348397 27898060 9393882 N/A physical interaction ComPPI,OmniPath
CBL TUBA1A 25348397 N/A physical interaction ComPPI
CBL SOS1 25348397 N/A physical interaction ComPPI
CBL NOTCH3 25348397 N/A physical interaction ComPPI
CBL SMAD3 25348397 N/A physical interaction ComPPI
CBL SFN 11697890 24234451 25348397 association physical interaction,biochemical ComPPI,IntAct
CBL YWHAH 11697890 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction,biochemical ComPPI,IntAct
CBL YWHAE 11697890 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction,biochemical ComPPI,IntAct
CBL RAPGEF1 25348397 N/A physical interaction ComPPI
CBL ABI1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
CBL CBLIF 25348397 N/A physical interaction ComPPI
CBL TCN1 25348397 N/A physical interaction ComPPI
CBL TCN2 25348397 N/A physical interaction ComPPI
CBL MYH2 25348397 N/A physical interaction ComPPI
CBL HTR2A 25348397 N/A physical interaction ComPPI
CBL FGFR2 25348397 N/A physical interaction ComPPI
CBL GBA 21098288 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL ITGAV 25348397 N/A physical interaction ComPPI
CBL BCAR1 25348397 N/A physical interaction ComPPI
CBL CD38 18974118 19635790 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CBL BCR 25348397 N/A physical interaction ComPPI
CBL GRAP2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CBL PIK3CA 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CBL SYNM 25348397 N/A physical interaction ComPPI
CBL CUBN 25348397 N/A physical interaction ComPPI
CBL SNX18 25348397 N/A physical interaction ComPPI
CBL KRT10 25348397 N/A physical interaction ComPPI
CBL KRT1 25348397 N/A physical interaction ComPPI
CBL PIK3CB 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CBL SPTBN1 25348397 N/A physical interaction ComPPI
CBL KRT9 25348397 N/A physical interaction ComPPI
CBL KRT14 25348397 N/A physical interaction ComPPI
CBL ACACA 25348397 N/A physical interaction ComPPI
CBL KRT16 25348397 N/A physical interaction ComPPI
CBL TUBB4B 25348397 N/A physical interaction ComPPI
CBL TUBA1C 25348397 N/A physical interaction ComPPI
CBL HSPA1L 25348397 N/A physical interaction ComPPI
CBL MYH10 25348397 N/A physical interaction ComPPI
CBL KRT17 25348397 N/A physical interaction ComPPI
CBL HSPA1A 25348397 N/A physical interaction ComPPI
CBL HSPA1B 25348397 N/A physical interaction ComPPI
CBL SPTA1 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CBL SPTAN1 25348397 N/A physical interaction ComPPI
CBL HSPA6 25348397 N/A physical interaction ComPPI
CBL CCT8 25348397 N/A physical interaction ComPPI
CBL RPS19 25348397 N/A physical interaction ComPPI
CBL CBLB 25348397 N/A physical interaction ComPPI
CBL KRT84 25348397 N/A physical interaction ComPPI
CBL CORO1C 25348397 N/A physical interaction ComPPI
CBL KRT3 25348397 N/A physical interaction ComPPI
CBL CAD 25348397 N/A physical interaction ComPPI
CBL ACTN1 25348397 N/A physical interaction ComPPI
CBL POP1 25348397 N/A physical interaction ComPPI
CBL PRKCQ 25348397 N/A physical interaction ComPPI
CBL MAP3K11 25348397 N/A physical interaction ComPPI
CBL UBE2D3 25348397 N/A physical interaction ComPPI
CBL TRPV1 25348397 N/A physical interaction ComPPI
CBL USP21 25348397 N/A physical interaction ComPPI
CBL ITGA4 25348397 N/A physical interaction ComPPI
CBL PTEN 25348397 N/A physical interaction ComPPI
CBL TNS4 25348397 N/A physical interaction ComPPI
CBL CTNNB1 23744067 25348397 25784557 27898060 N/A physical interaction ComPPI,OmniPath
CBL TRAF4 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CBL TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CBL IRF1 25348397 N/A physical interaction ComPPI
CBL FLT3 25348397 N/A physical interaction ComPPI
CBL LOX 25348397 N/A physical interaction ComPPI
CBL CAPZA1 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL PRPSAP2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL ERBB4 25348397 N/A physical interaction ComPPI
CBL SIRT2 25348397 N/A physical interaction ComPPI
CBL FLT1 18273061 24234451 25348397 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct
CBL TGFBR2 25348397 N/A physical interaction ComPPI
CBL ITPRID2 25348397 N/A physical interaction ComPPI
CBL SMAD7 25348397 N/A physical interaction ComPPI
CBL PIK3R3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping,validated two hybrid ComPPI,IntAct
CBL EPS8 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
CBL STAT3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
CBL MZF1 25348397 N/A physical interaction ComPPI
CBL SERPINA5 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CBL CEP170 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CBL CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CBL FBF1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CBL NPHP1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CBL XPO1 25348397 N/A physical interaction ComPPI
CBL PSMC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL XRCC5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CBL SP7 25348397 N/A physical interaction ComPPI
CBL ARHGEF6 25348397 N/A physical interaction ComPPI
CBL TGM2 25348397 N/A physical interaction ComPPI
CBL TSG101 25348397 N/A physical interaction ComPPI
CBL IRF3 25348397 N/A physical interaction ComPPI
CBL CDH1 25348397 N/A physical interaction ComPPI
CBL TRIM25 25348397 N/A physical interaction ComPPI
CBL TRAF2 25348397 N/A physical interaction ComPPI
CBL MYO1E 25348397 N/A two hybrid,physical interaction ComPPI
CBL FCGR1A 24234451 25348397 9716598 phosphorylation reaction experimental interaction detection ComPPI,IntAct
CBL STS 15159412 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CBL PTPRC 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL PTPRG 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL PTPRB 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL PTPRJ 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL PTPRO 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL SPRED2 17094949 24234451 25348397 27898060 association coimmunoprecipitation ComPPI,IntAct,OmniPath
CBL VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
CBL GOLM1 24234451 25348397 27569582 association anti tag coimmunoprecipitation ComPPI,IntAct
BLK CBL 14525934 24234451 25348397 8083187 8621719 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EIF5B CBL 14525934 25348397 8621719 N/A experimental interaction detection,in vivo ComPPI,HPRD
IQGAP1 CBL 25348397 N/A physical interaction ComPPI
YWHAQ CBL 11024037 11697890 14525934 15094368 24234451 25348397 8663231 9092538 association coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD,IntAct
HSPA9 CBL 25348397 N/A physical interaction ComPPI
SH3GL2 CBL 11894095 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
OSTF1 CBL 14525934 15135048 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
IGF1R CBL 14525934 18632619 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBL CBL 10078535 14525934 15677445 24234451 25814554 8063801 8995445 physical association experimental interaction detection,two hybrid array HPRD,IntAct
CBL DRK 24234451 9178769 N/A pull down IntAct
LMNA CBL 24234451 30021884 physical association cross-linking study IntAct
NGFR CBL 15337528 27898060 N/A N/A OmniPath
SRC CBL 10829062 11448952 11804588 11994282 12941616 14739300 15135048 15737992 16636290 17094785 17141222 17420256 18273061 19861161 22138575 22203672 27898060 7782294 8635998 8849724 9013636 stimulant N/A OmniPath
YES1 CBL 27898060 9525940 stimulant N/A OmniPath
LCK CBL 11741956 11904433 11994282 16107303 25784557 27898060 7721825 8551236 8621719 8626543 8900205 9115297 9178909 9890970 stimulant N/A OmniPath
PRKCA CBL 10358153 11024037 25814554 27898060 inhibition,stimulant N/A OmniPath
LYN CBL 10635327 11448952 12149655 12244174 14531861 15117950 15190072 18235045 27898060 7721825 7782294 8621719 8627181 8635998 9160881 9687507 9890970 stimulant N/A OmniPath
CBL LYN 12149655 12244174 14531861 15190072 18235045 27898060 7721825 7782294 8621719 8627181 8635998 9160881 9687507 9890970 N/A N/A OmniPath
CBL PIK3R2 11133830 11526404 15107835 19190244 19380743 25814554 27898060 7629144 8662998 9092574 inhibition N/A OmniPath
FYN CBL 10092522 10629042 10799548 10829062 11239464 11994282 12231245 12244174 12941616 15190072 15208330 15556646 15737992 16503409 17094785 19734451 25814554 27898060 7642581 7782294 8551236 8621719 8626543 8635998 8662998 8900205 8995358 9210408 9311917 9525940 9535867 9890970 stimulant N/A OmniPath
EGFR CBL 10086340 10092522 10428778 10635327 10799548 11239464 11370743 11408594 11823423 11994282 12061819 12593795 12604776 12734385 12803489 14505571 14627991 14691459 15107835 15117950 15159412 15210722 15282549 15383614 15465819 15556646 15668240 15677445 15735736 15737992 15962011 16105874 16246327 16497976 16729043 16829981 16849543 16923119 16969069 17139251 17182860 17242169 17372273 17389395 17486068 17545148 17880946 17971399 17995934 18271526 18273061 18316398 18508924 19155296 19225046 19531499 19578043 19713535 19836242 19947936 20029031 20124286 20298671 20332299 20562913 20877636 20940296 21772844 22203672 22266821 22394513 22591401 22833562 22976291 23027125 23153581 23158001 23175185 23418353 23457600 23774213 23799367 23897813 24714105 24797263 25140053 25521828 25872741 26055326 26177020 27898060 7592693 7657591 7782294 8550620 8662998 8798643 9121472 9130710 9178769 9756944 9890970 stimulant N/A OmniPath
CBL EGFR 10086340 10092522 10428778 10514377 10635327 10799548 11239464 11370743 11408594 11823423 11994282 12061819 12593795 12604776 12734385 12803489 14505571 14627991 14691459 15107835 15117950 15159412 15210722 15282549 15383614 15465819 15668240 15677445 15735736 15737992 15962011 16105874 16246327 16729043 16829981 16849543 16923119 16969069 17139251 17182860 17242169 17372273 17486068 17545148 17880946 17971399 17995934 18271526 18273061 18316398 18508924 19155296 19225046 19531499 19578043 19713535 19836242 19947936 20029031 20124286 20298671 20332299 20562913 20877636 20940296 21772844 22203672 22266821 22394513 22591401 22833562 22976291 23027125 23153581 23158001 23175185 23418353 23457600 23774213 23799367 23897813 24714105 24797263 25140053 25521828 25872741 26055326 26177020 27898060 7592693 7657591 7782294 8550620 8662998 8798643 9121472 9130710 9178769 9756944 9890970 inhibition,stimulant N/A OmniPath
HCK CBL 10092522 10799548 11239464 11896602 11994282 12032836 22974441 27898060 8995358 9890970 stimulant N/A OmniPath
TRAF6 CBL 11406619 27898060 N/A N/A OmniPath
SH3GLB1 CBL 11894095 27898060 stimulant N/A OmniPath
CBL SORBS2 12475393 15128873 27898060 inhibition N/A OmniPath
GRB2 CBL 10025673 10086340 10204582 10521482 10570290 10829062 11133830 11263968 11399323 11792427 11823423 11964172 11997436 12839496 12941616 14725908 15210722 15677445 16906159 169092 17072306 17094785 17372273 17944804 17971399 18273061 19380743 19836242 20124286 20936779 21703542 21706016 21725061 25036637 25814554 25872741 27898060 7537740 7592693 7642581 7657591 7791764 8063801 8083187 8621483 8621719 8626404 8635998 8649804 8662998 8695851 8824292 8900205 8943292 8950973 8995358 8995445 9092538 9108316 9108392 9129019 9174058 917890 9178909 9233773 9234717 9242692 9259313 9295052 9311917 9367879 9434624 9461587 9541596 9716598 9851874 98621719 9872323 stimulant N/A OmniPath
ABL1 CBL 10391678 10829062 11494134 11997497 12475393 14604282 14725908 15556646 16955467 17389395 19380743 19823681 20675402 20841568 27898060 8626543 8635998 9174058 9195915 9393882 stimulant N/A OmniPath
CBL ABL1 10391678 10829062 11494134 12475393 14604282 14725908 15556646 16955467 19380743 19823681 20675402 27898060 8626543 8635998 9174058 9195915 9393882 inhibition,stimulant N/A OmniPath
SORBS1 CBL 11001060 11997497 12504111 12765336 15128873 17548467 27898060 9447983 stimulant N/A OmniPath
CBL PIK3R1 10025673 10358153 10391678 10620516 10633073 10799548 10918571 10940298 11030146 11042121 11087752 11133830 11157475 11406619 11418612 11526404 11944898 11994282 14530346 15107835 15556646 15581361 15581362 16135792 16219545 16289966 16798838 16982329 17237826 17420256 18374639 19190244 19380743 19861161 20133944 21203488 24113870 25814554 27898060 7642581 7791764 8612729 8621719 8662998 8695807 8702998 8896416 8941725 8995243 9013636 9092538 9092574 9115297 9160881 9174058 9178909 9234717 9259313 9414268 9461587 9541596 9890943 9890970 9918857 9988765 inhibition N/A OmniPath
CRK CBL 10633073 10962563 11069064 11146548 11792427 11997497 12393469 15581361 15581362 16289966 18835194 19380743 20697350 22974441 25814554 27898060 8524328 8621483 8626404 8626543 8635998 8662998 8683103 8943292 9013636 9129019 9178909 9210408 9348226 9416834 9447983 9461587 9617486 9988765 stimulant N/A OmniPath
CBL ERBB2 12574167 20332299 26716506 27898060 inhibition N/A OmniPath
ABI1 CBL 17395426 27898060 stimulant N/A OmniPath
SH2B2 CBL 10374881 10854852 11498022 11997497 15031295 1573799 15737992 17620296 18273061 20298671 27898060 9233773 9989826 stimulant N/A OmniPath
ERBB4 CBL 16829981 18793634 27898060 stimulant N/A OmniPath
CBL MET 11894096 15123609 16397241 18273061 19433454 19450681 21163258 21222362 25241761 27898060 inhibition,stimulant N/A OmniPath
CD40 CBL 12637493 27898060 N/A N/A OmniPath
CBL CFLAR 19597496 27898060 inhibition N/A OmniPath
INSR CBL 10635327 10934191 11997497 12604776 15922744 15951569 27898060 stimulant N/A OmniPath
CBL INSR 10635327 11498022 11997497 27898060 inhibition N/A OmniPath
LTK CBL 27898060 9223670 stimulant N/A OmniPath
VAV1 CBL 11133830 11331248 12881521 16289966 16356860 18835194 19635790 27898060 920044 9200440 stimulant N/A OmniPath
CBL VAV1 11133830 11331248 12881521 16289966 16356860 18835194 19635790 27898060 920044 9200440 N/A N/A OmniPath
CBL SYK 10540342 10570266 10617633 11042121 11133830 11331248 11742985 12435267 15536084 15556646 15577829 15737992 16289966 18273061 27898060 7721825 8621719 9857068 inhibition N/A OmniPath
SYK CBL 10540342 10570266 10617633 10635327 10829062 11042121 11133830 11331248 11742985 12435267 15117950 15536084 15556646 15577829 15737992 15922744 16289966 18273061 27898060 7721825 8621719 9102067 9525940 9857068 N/A N/A OmniPath
CBL PDGFRA 10347229 27898060 9234717 inhibition,stimulant N/A OmniPath
CBL CD33 18062779 27898060 N/A N/A OmniPath
CBL FRS2 11997436 17944804 27898060 inhibition N/A OmniPath
FRS2 CBL 11997436 17944804 27898060 stimulant N/A OmniPath
CBL LRIG1 15282549 27898060 inhibition N/A OmniPath
LRIG1 CBL 15282549 27898060 stimulant N/A OmniPath
CBL AXL 15958209 27898060 N/A N/A OmniPath
SH3KBP1 CBL 10679202 11071869 11152963 11894095 11894096 12135478 12177062 12618476 12874286 14596919 15090612 15107835 15456872 16228008 16407834 17072306 17306257 17675467 19268472 19417776 19531213 20130058 20711168 21830225 22262777 22833562 24167568 25036637 25472714 27898060 stimulant N/A OmniPath
FGFR4 CBL 10608804 10829062 12604776 15922744 27898060 N/A N/A OmniPath
UBASH3B CBL 15159412 16429130 17675467 17880946 19380743 27898060 inhibition N/A OmniPath
PTPRJ CBL 19167335 19836242 27898060 N/A N/A OmniPath
PTPN22 CBL 10068674 27898060 inhibition N/A OmniPath

Visualization










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