Gene Information gene info

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GENE：FBXO4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FBXO4
FullNmae F-box protein 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13583
EnsembleID ENSG00000151876
Uniprot Q9UKT5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FBXO4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FBXO4 GO:0000151,GO:0000209,GO:0000209,GO:0004842,GO:0005515,GO:0005737,GO:0005829,GO:0010608,GO:0016567,GO:0016567,GO:0019005,GO:0019005,GO:0019725,GO:0031146,GO:0031146,GO:0031398,GO:0031647,GO:0031647,GO:0031648,GO:0032212,GO:0032212,GO:0035726,GO:0042803,GO:0048147,GO:0061630,GO:0071479,GO:0090398,GO:1900181,GO:1902916,GO:1990756,GO:2000001

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FBXO4 hsa:26272 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FBXO4 TERF1 16275645 19164295 19487455 20159592 22433952 26192618 interaction type N/A ACSN
FBXO4 CUL1 16278047 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO4 SKP1 16278047 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO4 LYL1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 FBXO4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FBXO4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FBXO4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FBXO4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FBXO4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 FBXO4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 FBXO4 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B FBXO4 22135298 phosphorylation N/A PhosphoSite
SKP1 FBXO4 25361965 interaction type N/A PTMCode2
FBXO4 SKP1 25361965 interaction type N/A PTMCode2
TERF1 FBXO4 25361965 interaction type N/A PTMCode2
FBXO4 TERF1 25361965 interaction type N/A PTMCode2
FBXO4 CUL1 25361965 interaction type N/A PTMCode2
CUL1 FBXO4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CCND1 FBXO4 25348397 N/A physical interaction ComPPI
SKP1 FBXO4 10531035 14525934 16278047 21242966 24234451 25348397 27705803 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
HSP90AB1 FBXO4 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
UBE2D2 FBXO4 25348397 N/A physical interaction ComPPI
HSP90AA1 FBXO4 25348397 N/A physical interaction ComPPI
AP1M1 FBXO4 25348397 N/A physical interaction ComPPI
NEDD8 FBXO4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AP1B1 FBXO4 25348397 N/A physical interaction ComPPI
CUL1 FBXO4 16278047 17353931 23108047 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAE FBXO4 21242966 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC34 FBXO4 25348397 N/A physical interaction ComPPI
PRKN FBXO4 25348397 N/A physical interaction ComPPI
FXR1 FBXO4 25348397 N/A physical interaction ComPPI
FMR1 FBXO4 25348397 N/A physical interaction ComPPI
ELAVL1 FBXO4 25348397 N/A physical interaction ComPPI
TERF1 FBXO4 14525934 16275645 19487455 20159592 20181953 24019069 24389012 25348397 27898060 N/A anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
TNNI3K FBXO4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FBXO4 ELF4 14525934 16581786 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FBXO4 FBXW8 25348397 N/A physical interaction ComPPI
FBXO4 TP53 25348397 N/A physical interaction ComPPI
FBXO4 HSP90AA2P 25348397 N/A physical interaction ComPPI
FBXO4 AMD1 25348397 N/A physical interaction ComPPI
FBXO4 DEFA1 25348397 N/A physical interaction ComPPI
FBXO4 ESPL1 25348397 N/A physical interaction ComPPI
FBXO4 FBXO4 21242966 24234451 association anti tag coimmunoprecipitation IntAct
GSK3B FBXO4 18187866 18598945 21242966 27898060 stimulant N/A OmniPath

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