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GENE：GZMM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GZMM
FullNmae granzyme M
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4712
EnsembleID ENSG00000197540
Uniprot P51124

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GZMM immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GZMM GO:0001913,GO:0004252,GO:0005515,GO:0005576,GO:0006508,GO:0006915,GO:0008236,GO:0016020,GO:0031640,GO:0045087

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GZMM SERPINA3 15494398 23180781 physical association comigration in sds page InnateDB
GZMM SERPINA1 15494398 23180781 protein cleavage,physical association comigration in sds page InnateDB
GZMM SERPINB9 15494398 23180781 protein cleavage protease assay InnateDB
GZMM CASP3 16818775 23180781 protein cleavage protease assay InnateDB
GZMM DFFA 16818775 23180781 protein cleavage protease assay InnateDB
GZMM PARP1 16818775 23180781 protein cleavage protease assay InnateDB
TRAP1 GZMM 17513296 23180781 protein cleavage protease assay InnateDB
GZMM TUBA4A 18523284 23180781 protein cleavage protease assay InnateDB
GZMM EZR 18523284 23180781 protein cleavage protease assay InnateDB
GZMM TUBA1B 18523284 23180781 protein cleavage protease assay InnateDB
GZMM NPM1 19103589 23180781 protein cleavage protease assay InnateDB
GZMM PAK2 19103589 23180781 protein cleavage protease assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GZMM 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 GZMM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GZMM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A GZMM 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA GZMM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GZMM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GZMM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GZMM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 GZMM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000023BE29 GZMM 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003D5391 GZMM 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 GZMM 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F GZMM 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ZNF774 GZMM 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NPM1 GZMM 25348397 N/A physical interaction ComPPI
TUBA1B GZMM 25348397 N/A physical interaction ComPPI
PARP1 GZMM 25348397 N/A physical interaction ComPPI
DFFA GZMM 25348397 N/A physical interaction ComPPI
EZR GZMM 25348397 N/A physical interaction ComPPI
GZMM TRAP1 17513296 27898060 N/A N/A OmniPath
GZMM MEA1 23146178 27898060 N/A N/A OmniPath
GZMM CASP3 16818775 27898060 N/A N/A OmniPath
GZMM PAK2 19103589 27898060 N/A N/A OmniPath

Visualization










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