Gene Information gene info

GENE:P2RX6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol P2RX6
FullNmae purinergic receptor P2X 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8538
EnsembleID ENSG00000099957
Uniprot O15547

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
P2RX6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
P2RX6 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
P2RX6 GO:0001614,GO:0004888,GO:0004931,GO:0004931,GO:0005524,GO:0005737,GO:0005886,GO:0005886,GO:0006936,GO:0007165,GO:0015267,GO:0030054,GO:0030054,GO:0033198,GO:0035590,GO:0043025,GO:0043197,GO:0043235,GO:0044877,GO:0060079,GO:0070588,GO:0098688,GO:0098978,GO:0099634

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
P2RX6 hsa:9127 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
P2RX6 hsa:9127 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTCF P2RX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 P2RX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 P2RX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS P2RX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A P2RX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 P2RX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 P2RX6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA P2RX6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDH5 P2RX6 25361965 interaction type N/A PTMCode2
P2RX6 CDH5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDH5 P2RX6 12088286 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SRPK1 P2RX6 23602568 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
P2RX6 APP 25348397 N/A physical interaction ComPPI
P2RX6 DNAJB5 25348397 N/A physical interaction ComPPI
P2RX6 DNAJB4 25348397 N/A physical interaction ComPPI
P2RX6 BAG5 25348397 N/A physical interaction ComPPI
TP53 P2RX6 18431400 27898060 stimulant N/A OmniPath

Visualization