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GENE：PTPRK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPRK
FullNmae protein tyrosine phosphatase receptor type K
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9674
EnsembleID ENSG00000152894
Uniprot Q15262

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPRK pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPRK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPRK GO:0004725,GO:0004725,GO:0005001,GO:0005515,GO:0005886,GO:0005886,GO:0005911,GO:0005912,GO:0006470,GO:0006470,GO:0007155,GO:0007165,GO:0007179,GO:0008013,GO:0008285,GO:0009986,GO:0010839,GO:0016020,GO:0016477,GO:0019901,GO:0030054,GO:0030336,GO:0031256,GO:0034394,GO:0034614,GO:0034644,GO:0043231,GO:0045295,GO:0045786,GO:0045892,GO:0048041

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GADD45G PTPRK 20005715 interaction type N/A PSP
PXN PTPRK 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
AR PTPRK 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PTPRK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PTPRK 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PTPRK 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PTPRK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000032BD73 PTPRK 23451058 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000065D58 PTPRK 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS000032BD73 PTPRK 23451058 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000033EBB8 PTPRK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D PTPRK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PTPRK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 PTPRK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PTPRK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C02E4 PTPRK 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 PTPRK 25348397 N/A physical interaction ComPPI
PKP4 PTPRK 25348397 N/A physical interaction ComPPI
GADD45G PTPRK 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
BMP7 PTPRK 25348397 N/A physical interaction ComPPI
TK1 PTPRK 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HYAL2 PTPRK 25348397 N/A physical interaction ComPPI
TUFM PTPRK 25348397 N/A physical interaction ComPPI
ERBB2 PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CBL PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
DGCR2 PTPRK 25348397 N/A physical interaction ComPPI
TEC PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PIK3R1 PTPRK 25348397 N/A physical interaction ComPPI
LCK PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
WNT5A PTPRK 25348397 N/A physical interaction ComPPI
MAPK3 PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PSMD11 PTPRK 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
JUP PTPRK 14525934 25348397 8663237 N/A experimental interaction detection,physical interaction ComPPI,HPRD
COL6A2 PTPRK 25348397 N/A physical interaction ComPPI
PDGFRB PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
GHR PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PLAT PTPRK 25348397 N/A physical interaction ComPPI
LAMA3 PTPRK 25348397 N/A physical interaction ComPPI
LRP1B PTPRK 25348397 N/A physical interaction ComPPI
PDPK1 PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
COL4A2 PTPRK 25348397 N/A physical interaction ComPPI
PXN PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
SCARB1 PTPRK 25348397 N/A physical interaction ComPPI
RPL28 PTPRK 25348397 N/A physical interaction ComPPI
ADAM9 PTPRK 25348397 N/A physical interaction ComPPI
BCHE PTPRK 25348397 N/A physical interaction ComPPI
PCSK5 PTPRK 25348397 N/A physical interaction ComPPI
SP3 PTPRK 25348397 N/A physical interaction ComPPI
CSK PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
NSF PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
MET PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
EGFR PTPRK 25348397 N/A physical interaction ComPPI
SCARB2 PTPRK 25348397 N/A physical interaction ComPPI
PLXNA1 PTPRK 25348397 N/A physical interaction ComPPI
CTNNB1 PTPRK 14525934 25348397 8663237 N/A experimental interaction detection,physical interaction ComPPI,HPRD
LAMB1 PTPRK 25348397 N/A physical interaction ComPPI
RIPK3 PTPRK 25348397 N/A physical interaction ComPPI
MEGF8 PTPRK 25348397 N/A physical interaction ComPPI
ITGA4 PTPRK 25348397 N/A physical interaction ComPPI
LGALS8 PTPRK 25348397 N/A physical interaction ComPPI
FBLN1 PTPRK 25348397 N/A physical interaction ComPPI
ATP2A2 PTPRK 25348397 N/A physical interaction ComPPI
FKBP8 PTPRK 25348397 N/A physical interaction ComPPI
INSR PTPRK 19167335 24234451 25348397 dephosphorylation reaction physical interaction,phosphatase assay ComPPI,IntAct
LAMA5 PTPRK 25348397 N/A physical interaction ComPPI
ECE1 PTPRK 25348397 N/A physical interaction ComPPI
MINK1 PTPRK 25348397 N/A physical interaction ComPPI
ARSA PTPRK 25348397 N/A physical interaction ComPPI
PLXNA2 PTPRK 25348397 N/A physical interaction ComPPI
GNPTG PTPRK 25348397 N/A physical interaction ComPPI
CDH2 PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CNTNAP3 PTPRK 25348397 N/A physical interaction ComPPI
PTPRU PTPRK 25348397 N/A physical interaction ComPPI
PLXNB2 PTPRK 25348397 N/A physical interaction ComPPI
CSNK2B PTPRK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TMEM132A PTPRK 25348397 N/A physical interaction ComPPI
MMP26 PTPRK 25348397 N/A physical interaction ComPPI
SEC24B PTPRK 25348397 N/A physical interaction ComPPI
ERO1B PTPRK 25348397 N/A physical interaction ComPPI
ITGA8 PTPRK 25348397 N/A physical interaction ComPPI
AMIGO1 PTPRK 25348397 N/A physical interaction ComPPI
AMIGO3 PTPRK 25348397 N/A physical interaction ComPPI
MICA PTPRK 25348397 N/A physical interaction ComPPI
GADD45A PTPRK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
COL6A1 PTPRK 25348397 N/A physical interaction ComPPI
DEFA5 PTPRK 25348397 N/A physical interaction ComPPI
MAN2A2 PTPRK 25348397 N/A physical interaction ComPPI
NID2 PTPRK 25348397 N/A physical interaction ComPPI
GLG1 PTPRK 25348397 N/A physical interaction ComPPI
LOX PTPRK 21690299 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
TMEM67 PTPRK 25348397 N/A physical interaction ComPPI
CTSF PTPRK 25348397 N/A physical interaction ComPPI
SUSD1 PTPRK 25348397 N/A physical interaction ComPPI
PTPRK LGALS9 25348397 N/A physical interaction ComPPI
PTPRK LAMB2 25348397 N/A physical interaction ComPPI
PTPRK ATRN 25348397 N/A physical interaction ComPPI
PTPRK CACNA2D2 25348397 N/A physical interaction ComPPI
PTPRK CES3 25348397 N/A physical interaction ComPPI
PTPRK TCTN2 25348397 N/A physical interaction ComPPI
PTPRK PXDN 25348397 N/A physical interaction ComPPI
PTPRK FRAS1 25348397 N/A physical interaction ComPPI
PTPRK CACNA2D1 25348397 N/A physical interaction ComPPI
PTPRK CD109 25348397 N/A physical interaction ComPPI
PTPRK POGLUT1 25348397 N/A physical interaction ComPPI
PTPRK ARSK 25348397 N/A physical interaction ComPPI
PTPRK UBR3 25348397 N/A physical interaction ComPPI
PTPRK GALNS 25348397 N/A physical interaction ComPPI
PTPRK ARSG 25348397 N/A physical interaction ComPPI
PTPRK LRIG3 25348397 N/A physical interaction ComPPI
PTPRK LRIG1 25348397 N/A physical interaction ComPPI
PTPRK B3GLCT 25348397 N/A physical interaction ComPPI
PTPRK NPC1 25348397 N/A physical interaction ComPPI
PTPRK EOGT 25348397 N/A physical interaction ComPPI
PTPRK PLXNA3 25348397 N/A physical interaction ComPPI
PTPRK MOXD1 25348397 N/A physical interaction ComPPI
PTPRK CCDC102A 25348397 N/A physical interaction ComPPI
PTPRK CHST10 25348397 N/A physical interaction ComPPI
PTPRK DNAJB9 25348397 N/A physical interaction ComPPI
PTPRK MAN2A1 25348397 N/A physical interaction ComPPI
PTPRK MANBA 25348397 N/A physical interaction ComPPI
PTPRK MGRN1 25348397 N/A physical interaction ComPPI
PTPRK ARSB 25348397 N/A physical interaction ComPPI
PTPRK CLN5 25348397 N/A physical interaction ComPPI
PTPRK FUT11 25348397 N/A physical interaction ComPPI
PTPRK CERCAM 25348397 N/A physical interaction ComPPI
PTPRK DCBLD2 25348397 N/A physical interaction ComPPI
PTPRK CHST12 25348397 N/A physical interaction ComPPI
PTPRK SIAE 25348397 N/A physical interaction ComPPI
PTPRK GALNT18 25348397 N/A physical interaction ComPPI
PTPRK P3H3 25348397 N/A physical interaction ComPPI
PTPRK BTD 25348397 N/A physical interaction ComPPI
PTPRK ANKRD46 25348397 N/A physical interaction ComPPI
PTPRK SIPA1L3 25348397 N/A physical interaction ComPPI
PTPRK ARHGAP32 25348397 N/A physical interaction ComPPI
PTPRK TANC1 25348397 N/A physical interaction ComPPI
PTPRK NCKAP5L 25348397 N/A physical interaction ComPPI
PTPRK PEAK1 25348397 N/A physical interaction ComPPI
PTPRK PCDHGB1 25348397 N/A physical interaction ComPPI
PTPRK PCDHGB4 25348397 N/A physical interaction ComPPI
PTPRK LYPD1 25348397 N/A physical interaction ComPPI
PTPRK ZNF3 25348397 N/A physical interaction ComPPI
PTPRK TMPRSS11B 25348397 N/A physical interaction ComPPI
PTPRK TEK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PTPRK PTPRM 14525934 27898060 7782276 N/A experimental interaction detection HPRD,OmniPath
PTPRK PTPRK 14525934 15978577 24234451 8264577 association experimental interaction detection,tox-r dimerization assay HPRD,IntAct
PTPRK CTNNB1 27898060 8663237 N/A N/A OmniPath
PTPRK EGFR 16263724 27898060 inhibition N/A OmniPath

Visualization










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