GENE：POLQ
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | POLQ |
| FullNmae | DNA polymerase theta |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9186 |
| EnsembleID | ENSG00000051341 |
| Uniprot | O75417 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| POLQ | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| POLQ | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| POLQ | GO:0003682,GO:0003684,GO:0003887,GO:0003887,GO:0003887,GO:0005515,GO:0005524,GO:0005654,GO:0005654,GO:0005694,GO:0005794,GO:0005829,GO:0006261,GO:0006281,GO:0006284,GO:0006302,GO:0006974,GO:0016446,GO:0017116,GO:0032508,GO:0051260,GO:0051575,GO:0071897,GO:0097681,GO:0097681,GO:2000042 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | POLQ | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | POLQ | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | POLQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | POLQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | POLQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | POLQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | POLQ | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| IRF1 | POLQ | 22367195 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000AA464 | POLQ | 20304954 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | POLQ | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00004A9320 | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | POLQ | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | POLQ | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003003B4 | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017DBB8 | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000412AC7 | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759EB8 | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020CEC2 | POLQ | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ED720 | POLQ | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F31F4 | POLQ | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | POLQ | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB14 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A052 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021202F | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000011166D | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEF5F | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | POLQ | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EE7F0 | POLQ | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000030F801 | POLQ | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | POLQ | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | POLQ | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | POLQ | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | POLQ | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RAD51 | POLQ | 25348397 25642963 27898060 | N/A | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,OmniPath |
| AP2S1 | POLQ | 25348397 | N/A | physical interaction | ComPPI |
| RBM25 | POLQ | 24234451 30021884 | physical association | cross-linking study | IntAct |