Gene Information gene info

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GENE：KYNU

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KYNU
FullNmae kynureninase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6469
EnsembleID ENSG00000115919
Uniprot Q16719

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KYNU immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KYNU GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0006569,GO:0009435,GO:0019441,GO:0019805,GO:0030170,GO:0030429,GO:0030429,GO:0030429,GO:0034341,GO:0034354,GO:0034516,GO:0042803,GO:0043420,GO:0043420,GO:0061981,GO:0097053

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KYNU hsa:8942 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
KYNU hsa:8942 path:hsa01100 Metabolic pathways - Homo sapiens (human)
KYNU hsa:8942 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR KYNU 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 KYNU 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 KYNU 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 KYNU 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C KYNU 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KYNU 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000CF1D2 KYNU 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 KYNU 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 KYNU 21572407 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004719AB KYNU 21572407 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000085F64 KYNU 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 KYNU 21572407 23313552 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SGTA KYNU 25348397 N/A physical interaction ComPPI
LDHA KYNU 25348397 N/A physical interaction ComPPI
CFL1 KYNU 25348397 N/A physical interaction ComPPI
COIL KYNU 25348397 N/A physical interaction ComPPI
LYN KYNU 25348397 N/A physical interaction ComPPI
DSTN KYNU 25348397 N/A physical interaction ComPPI
NAGK KYNU 25348397 N/A physical interaction ComPPI
GLRX KYNU 25348397 N/A physical interaction ComPPI
RPS6KA1 KYNU 25348397 N/A physical interaction ComPPI
NDRG1 KYNU 25348397 N/A physical interaction ComPPI
TPM3 KYNU 25348397 N/A physical interaction ComPPI
BCCIP KYNU 25348397 N/A physical interaction ComPPI
SPR KYNU 25348397 N/A physical interaction ComPPI
RET KYNU 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FUBP1 KYNU 25348397 N/A physical interaction ComPPI
SIRT1 KYNU 25348397 N/A physical interaction ComPPI
CSE1L KYNU 25348397 N/A physical interaction ComPPI
GDA KYNU 25348397 N/A physical interaction ComPPI
PPIA KYNU 25348397 N/A physical interaction ComPPI
MVD KYNU 25348397 N/A physical interaction ComPPI
SMARCD2 KYNU 25348397 N/A physical interaction ComPPI
KHSRP KYNU 25348397 N/A physical interaction ComPPI
NUP210 KYNU 25348397 N/A physical interaction ComPPI
ADSS2 KYNU 25348397 N/A physical interaction ComPPI
SEC23IP KYNU 25348397 N/A physical interaction ComPPI
ASNS KYNU 25348397 N/A physical interaction ComPPI
GSR KYNU 25348397 N/A physical interaction ComPPI
FH KYNU 25348397 N/A physical interaction ComPPI
NXF1 KYNU 25348397 N/A physical interaction ComPPI
PPM1G KYNU 25348397 N/A physical interaction ComPPI
SSU72 KYNU 25348397 N/A physical interaction ComPPI
KYNU ADK 25348397 N/A physical interaction ComPPI

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