GENE:PTPRD
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PTPRD |
| FullNmae | protein tyrosine phosphatase receptor type D |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9668 |
| EnsembleID | ENSG00000153707 |
| Uniprot | P23468 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PTPRD | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PTPRD | GO:0004725,GO:0005001,GO:0005102,GO:0005515,GO:0005886,GO:0006470,GO:0006470,GO:0006796,GO:0007157,GO:0007185,GO:0030182,GO:0042734,GO:0046426,GO:0050775,GO:0050776,GO:0050804,GO:0050839,GO:0051965,GO:0070062,GO:0097105,GO:0098685,GO:0098686,GO:0098978,GO:0098978,GO:0099054,GO:0099054,GO:0099151,GO:0099545,GO:0099545,GO:0099560,GO:0099560,GO:0099560 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PTPRD | hsa:5789 | path:hsa04514 | Cell adhesion molecules - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PPFIA1 | PTPRD | 20005715 | interaction type | N/A | PSP |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PTPRD | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXP3 | PTPRD | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | PTPRD | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | PTPRD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003E1A9 | PTPRD | 20005803 | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS000008DA94 | PTPRD | 20005803 | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS000012A1DD | PTPRD | 20005803 | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS0000171525 | PTPRD | 20005803 | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS000055BBE5 | PTPRD | 20005803 | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS000055BBE5 | PTPRD | 20005803 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000008DA94 | PTPRD | 20005803 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000171525 | PTPRD | 20005803 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000003E1A9 | PTPRD | 20005803 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000012A1DD | PTPRD | 20005803 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00004719AB | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFEC1 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007FBA | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000002CF68 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028C188 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F6E49 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | PTPRD | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TPP2 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| PPFIA1 | PTPRD | 14525934 25348397 8524829 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| CSNK1D | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| TRIO | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| DSC3 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| CSNK1E | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| PLK1 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| LILRB4 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| PTPRS | PTPRD | 14525934 25348397 27898060 9566880 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD,OmniPath |
| RPL28 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| EPHA8 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| NEK2 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| PPFIA2 | PTPRD | 14525934 25348397 9624153 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| PPFIA3 | PTPRD | 14525934 25348397 9624153 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| MDM2 | PTPRD | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| EGFR | PTPRD | 24189400 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| IRS1 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| MARK2 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| BMX | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| NEK1 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| AURKA | PTPRD | 22305495 24234451 25348397 | physical association | anti tag coimmunoprecipitation,protein array | ComPPI,IntAct |
| IL2RG | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| FYN | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| NLGN3 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| PAK6 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| TRIM25 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| TBK1 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| MTNR1A | PTPRD | 24234451 25348397 26514267 | physical association | ubiquitin reconstruction,physical interaction | ComPPI,IntAct |
| COPG2 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| DDX54 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| LITAF | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| TSSK2 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| GPR37 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| NEK6 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| IL20RA | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| ABCG8 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| ICOSLG | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| ABLIM1 | PTPRD | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| IL17RD | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| MTSS1 | PTPRD | 12570871 14525934 25348397 27898060 | N/A | affinity chromatography technology,two hybrid,experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD,OmniPath |
| STMN4 | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| MTNR1B | PTPRD | 24234451 25348397 26514267 | physical association | ubiquitin reconstruction,physical interaction | ComPPI,IntAct |
| HADHB | PTPRD | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | LPAR6 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | SCN2B | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | LRRTM2 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | HADHA | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | LRRN1 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | PCDHB16 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | PIANP | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | CD83 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | PMEL | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | PCDH20 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | IZUMO1 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | PCDHGB4 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | TEX45 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | ARHGAP36 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | LINGO2 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | MILR1 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | TMEM52B | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | TPCN2 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | TMEM223 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRD | SLAIN2 | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| PTPRD | SMTNL2 | 22305495 24234451 25348397 | N/A | protein array | ComPPI,IntAct |
| PTPRD | PTPRA | 10777529 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
| PTPRD | PTPRE | 12376545 14525934 | N/A | experimental interaction detection | HPRD |
| PTPRD | PTPRF | 12376545 14525934 | N/A | experimental interaction detection | HPRD |
| PTPRD | PTPRD | 15978577 24234451 | association | tox-r dimerization assay | IntAct |
| PTPRD | STAT3 | 19478061 20418918 27898060 | inhibition | N/A | OmniPath |
