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GENE：CDK16

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK16
FullNmae cyclin dependent kinase 16
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8749
EnsembleID ENSG00000102225
Uniprot Q00536

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK16 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDK16 GO:0000083,GO:0000307,GO:0004674,GO:0004693,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0006468,GO:0006468,GO:0006887,GO:0006887,GO:0007283,GO:0007283,GO:0008021,GO:0008021,GO:0009898,GO:0010508,GO:0015630,GO:0030252,GO:0031175,GO:0031175,GO:0043005,GO:0051726,GO:0061178,GO:0106310

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP CDK16 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CDK16 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CDK16 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CDK16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CDK16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CDK16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC CDK16 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE CDK16 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F CDK16 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002FC5B0 CDK16 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 CDK16 25416803 27073545 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001A7F58 CDK16 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000050CCE0 CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000035CC3E CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003804D8 CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017CCCB CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004818BD CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000020579D CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CC20C CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000209F04 CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036AFF1 CDK16 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA CDK16 22135298 phosphorylation N/A PhosphoSite
CDK16 PRKAR1A 22135298 phosphorylation N/A PhosphoSite
CDK16 CDKN1B 22135298 phosphorylation N/A PhosphoSite
CDK16 CCNY 22135298 phosphorylation N/A PhosphoSite
BRSK2 CDK16 22135298 phosphorylation N/A PhosphoSite
CDK2 CDK16 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
FAM110A CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SH3KBP1 CDK16 25348397 N/A physical interaction ComPPI
ZBTB14 CDK16 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EDC3 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PTS CDK16 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
LMNA CDK16 25348397 N/A physical interaction ComPPI
FAM53C CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YWHAG CDK16 12154078 14525934 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CDK5R1 CDK16 12084709 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
APPBP2 CDK16 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CBY1 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TIAM1 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GAB2 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HDAC4 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RTKN CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF1 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRKACA CDK16 12154078 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
YWHAB CDK16 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ CDK16 12154078 14525934 24234451 25348397 25852190 9197417 association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
BAG6 CDK16 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAGI1 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CSNK2A1 CDK16 25348397 N/A physical interaction ComPPI
PHLDB2 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PPP2CB CDK16 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CILK1 CDK16 25348397 N/A physical interaction ComPPI
PKM CDK16 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB3IP CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
XPO1 CDK16 25348397 N/A physical interaction ComPPI
YWHAQ CDK16 25348397 N/A physical interaction ComPPI
CSNK2A2 CDK16 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK2 CDK16 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAH CDK16 14525934 25348397 9799109 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
YWHAE CDK16 12154078 14525934 24234451 25348397 25852190 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MELK CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GTF2F1 CDK16 25348397 N/A physical interaction ComPPI
SH3PXD2A CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PPP2R2A CDK16 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TBC1D25 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK5 CDK16 12084709 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CDK8 CDK16 25348397 N/A physical interaction ComPPI
PJA1 CDK16 25348397 N/A physical interaction ComPPI
CDK16 SEC23A 14525934 16091426 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CDK16 BRCA1 25348397 N/A physical interaction ComPPI
CDK16 S100A10 25348397 N/A physical interaction ComPPI
CDK16 APP 25348397 N/A physical interaction ComPPI
CDK16 CSNK2B 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDK16 ATRIP 25348397 N/A physical interaction ComPPI
CDK16 CCNYL1 22184064 24234451 25348397 25852190 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
CDK16 CDK17 25348397 N/A physical interaction ComPPI
CDK16 CDK18 25348397 N/A physical interaction ComPPI
CDK16 PPP2R2D 25348397 N/A physical interaction ComPPI
CDK16 SNX27 25348397 N/A physical interaction ComPPI
CDK16 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CDK16 ISG20L2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK16 NUP54 25348397 N/A physical interaction ComPPI
CDK16 CCNY 22184064 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK16 MCMBP 25348397 N/A physical interaction ComPPI
CDK16 KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 ZBTB21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 DENND1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SRGAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SIPA1L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 LIMA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 TESK2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 DCLK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 ZNF638 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SRSF12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SYDE1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 AGAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 CDC25B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 FAM110B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 USP21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 ANKRD34A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 PPM1H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 MAPKAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 MAST3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 DENND4C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 NADK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 MAP3K21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 NF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 RASAL2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 CGN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 PLEKHA7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 AFDN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 DEPDC1B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 KIF1C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 CAMSAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 PLEKHA5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CDK16 SEC24D 16091426 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 CCNI 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 CCNK 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 SPDYA 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 FBXO8 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 MIF4GD 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 CFAP20DC 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 TMEM99 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 UAP1 22184064 24234451 25348397 physical association two hybrid ComPPI,IntAct
CDK16 CDK16 14525934 17192257 N/A experimental interaction detection HPRD
CDK5 CDK16 12084709 18691976 27898060 N/A N/A OmniPath
PRKACA CDK16 12154078 17322306 18212344 18669648 18691976 18767875 19651622 20068231 22184064 22798068 26305884 27898060 inhibition N/A OmniPath
ATM CDK16 12084709 12154078 27898060 N/A N/A OmniPath
CDK16 PRKAR1A 16582606 25605337 27898060 N/A N/A OmniPath
CDK16 CCNY 22184064 26205494 27898060 N/A N/A OmniPath

Visualization










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