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GENE：SERPINB9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERPINB9
FullNmae serpin family B member 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8955
EnsembleID ENSG00000170542
Uniprot P50453

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERPINB9 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SERPINB9 GO:0002020,GO:0002448,GO:0004867,GO:0004867,GO:0005515,GO:0005615,GO:0005615,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005794,GO:0005829,GO:0006955,GO:0010951,GO:0010951,GO:0016020,GO:0042270,GO:0043027,GO:0043027,GO:0043066,GO:0062023,GO:0070062,GO:0071391

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERPINB9 hsa:5272 path:hsa05146 Amoebiasis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GZMB SERPINB9 11278311 11485349 15494398 16405655 16547231 17116752 23180781 9182575 9774654 physical association anti tag coimmunoprecipitation,comigration in gel electrophoresis,comigration in sds page InnateDB
GZMM SERPINB9 15494398 23180781 protein cleavage protease assay InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 SERPINB9 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 SERPINB9 11682627 14617632 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
ETS1 SERPINB9 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SERPINB9 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SERPINB9 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000076995 SERPINB9 21880628 25416803 mrna cleavage,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 SERPINB9 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000007340 SERPINB9 24517116 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SERPINB9 CASP4 10477277 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SERPINB9 EEF1A1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 GAPDH 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 XRCC6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 TLE1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 CRMP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 UNC119 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 ERG28 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 SETDB1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 UBR1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 ZHX1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 PRPF40A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 IGSF21 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SERPINB9 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SERPINB9 RBM48 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 CCDC90B 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 MED31 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 COPS6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
SERPINB9 GBP2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 ECH1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 PLEKHM1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 GDF9 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 TP53 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SERPINB9 TUBB2A 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SERPINB9 EEF1A1P5 25348397 N/A physical interaction ComPPI
SERPINB9 GZMB 14525934 25348397 8910377 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SERPINB9 CDK2 25348397 N/A physical interaction ComPPI
SERPINB9 CD81 25348397 N/A physical interaction ComPPI
SERPINB9 IGSF8 25348397 N/A physical interaction ComPPI
SERPINB9 TRAF5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SERPINB9 CASP1 25348397 N/A physical interaction ComPPI
SERPINB9 MCM2 25348397 N/A physical interaction ComPPI
SERPINB9 VAPA 25348397 N/A physical interaction ComPPI
SERPINB9 CASP8 25348397 N/A physical interaction ComPPI
SERPINB9 CASP10 25348397 N/A physical interaction ComPPI
SERPINB9 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SERPINB9 CASP1 10477277 27898060 inhibition N/A OmniPath

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