Gene Information gene info

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GENE：TP53RK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TP53RK
FullNmae TP53 regulating kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16197
EnsembleID ENSG00000172315
Uniprot Q96S44

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TP53RK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TP53RK GO:0000408,GO:0000408,GO:0002039,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006468,GO:0006468,GO:0008033,GO:0016787,GO:0070525,GO:0106310,GO:1901796

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AKT1 TP53RK 17712528 23180781 phosphorylation reaction in-gel kinase assay,protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 TP53RK 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TP53RK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TP53RK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TP53RK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TP53RK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TP53RK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000017EA6A TP53RK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000427B68 TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000009C45F TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 TP53RK 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TP53RK TP53 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
AKT1 TP53RK 22135298 phosphorylation N/A PhosphoSite
TPRKB TP53RK 25361965 interaction type N/A PTMCode2
TP53RK TPRKB 25361965 interaction type N/A PTMCode2
TP53 TP53RK 25361965 interaction type N/A PTMCode2
GLRX3 TP53RK 25361965 interaction type N/A PTMCode2
TP53RK GLRX3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TPD52L2 TP53RK 25348397 N/A physical interaction ComPPI
GLRX3 TP53RK 25348397 N/A physical interaction ComPPI
LAGE3 TP53RK 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TP53RK TPRKB 16189514 23414517 23455922 24234451 25348397 association,physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,tandem affinity purification ComPPI,IntAct
TP53RK CALCOCO2 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
TP53RK TP53 11546806 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TP53RK ELAVL1 25348397 N/A physical interaction ComPPI
TP53RK PRAME 25348397 N/A physical interaction ComPPI
TP53RK OSGEP 23414517 23455922 24234451 25348397 association,physical association physical interaction,two hybrid fragment pooling approach,tandem affinity purification ComPPI,IntAct
TP53RK GON7 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TP53RK HSP90AA1 25348397 N/A physical interaction ComPPI
TP53RK HSP90AA2P 25348397 N/A physical interaction ComPPI
TP53RK AARSD1 25348397 N/A physical interaction ComPPI
TP53RK KIFBP 25348397 N/A physical interaction ComPPI
TP53RK METTL1 25348397 N/A physical interaction ComPPI
TP53RK NIF3L1 25348397 N/A physical interaction ComPPI
TP53RK NSUN2 25348397 N/A physical interaction ComPPI
TP53RK PANK4 25348397 N/A physical interaction ComPPI
TP53RK PRKACB 25348397 N/A physical interaction ComPPI
TP53RK RANGAP1 25348397 N/A physical interaction ComPPI
TP53RK SAE1 25348397 N/A physical interaction ComPPI
TP53RK SH3GL1 25348397 N/A physical interaction ComPPI
TP53RK THG1L 25348397 N/A physical interaction ComPPI
TP53RK TOM1L1 25348397 N/A physical interaction ComPPI
TP53RK ACTR2 25348397 N/A physical interaction ComPPI
TP53RK ACTR3 25348397 N/A physical interaction ComPPI
TP53RK DPP9 25348397 N/A physical interaction ComPPI
TP53RK EEF2K 25348397 N/A physical interaction ComPPI
TP53RK EFL1 25348397 N/A physical interaction ComPPI
TP53RK RPRD1B 25348397 N/A physical interaction ComPPI
TP53RK UFM1 25348397 N/A physical interaction ComPPI
TP53RK SMS 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TP53RK NUP43 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TP53RK PATJ 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TP53RK MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TP53RK MEOX1 25348397 N/A physical interaction ComPPI
TP53RK STX19 25348397 N/A physical interaction ComPPI
TP53RK LURAP1L 25348397 N/A physical interaction ComPPI
TP53RK MBIP 25348397 N/A physical interaction ComPPI
TP53RK COMMD4 25348397 N/A physical interaction ComPPI
TP53RK ARPP19 25348397 N/A physical interaction ComPPI
TP53RK PRPS1 25348397 N/A physical interaction ComPPI
TP53RK CTH 25348397 N/A physical interaction ComPPI
TP53RK VARS1 25348397 N/A physical interaction ComPPI
TP53RK WDR4 25348397 N/A physical interaction ComPPI
TP53RK CHN2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TP53RK CLK1 25348397 N/A physical interaction ComPPI
TP53RK MDM2 25348397 N/A physical interaction ComPPI
TP53RK MTMR10 25348397 N/A physical interaction ComPPI
TP53RK NELL1 25348397 N/A physical interaction ComPPI
TP53RK UBA5 25348397 N/A physical interaction ComPPI
TP53RK COMMD10 25348397 N/A physical interaction ComPPI
TP53RK PLPPR2 25348397 N/A physical interaction ComPPI
TP53RK MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TP53RK DCTN1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TP53RK LRRC2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TP53RK SYNE1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TP53RK HSP90AB1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TP53RK GORASP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CALU TP53RK 25348397 N/A physical interaction ComPPI
TP53RK TP53RK 24722188 25416956 30476227 N/A two hybrid TheBiogrid
AKT1 TP53RK 17712528 27898060 stimulant N/A OmniPath
TP53RK TP53 10611322 10713094 10723129 10958792 11096068 11121242 11546806 11711532 12049739 12071847 12080066 12082529 12151394 12324477 12393500 12511424 12518062 12606585 12637545 12702572 12771937 12890678 12939400 14871840 14871926 15048074 15077171 15078887 15082766 15178764 15181149 15226429 15258567 15310764 15361830 15456784 15489892 15533933 15665826 15782130 15794754 15866171 15897882 16223874 16247456 16288207 16397295 16478990 16489034 16636671 16648554 16818505 16891474 16916644 17234789 17297446 17332358 17371838 17456577 17486112 17535811 17596534 17609585 17616578 17668048 17712528 17936559 18032786 18056442 18216278 18332866 18339864 18345031 18381438 18406507 18604166 18614045 18785202 18818083 18985806 19085961 19266268 19303885 19828454 19907922 19934315 19962312 20353948 20372057 20661218 20711232 20931131 20935676 21317290 21394211 21441950 21465263 21642861 21660965 21765463 22002314 22055193 23148227 23150668 23184057 23678107 24038750 24608431 24820418 24958101 25088203 25202122 25651062 25860929 25915850 26104798 27898060 9733515 9843217 stimulant N/A OmniPath

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