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GENE：NEB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NEB
FullNmae nebulin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7720
EnsembleID ENSG00000183091
Uniprot P20929

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NEB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NEB GO:0005515,GO:0005829,GO:0007517,GO:0007525,GO:0008307,GO:0015629,GO:0030018,GO:0030018,GO:0030832,GO:0051015,GO:0070062,GO:0071691

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 NEB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NEB 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 NEB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 NEB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
DES NEB 25361965 interaction type N/A PTMCode2
NEB DES 25361965 interaction type N/A PTMCode2
TRIM63 NEB 25361965 interaction type N/A PTMCode2
NEB TRIM63 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DES NEB 12064939 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
CALM1 NEB 25348397 N/A physical interaction ComPPI
ROCK1 NEB 21281639 24234451 25348397 association pull down ComPPI,IntAct
KEAP1 NEB 25348397 N/A physical interaction ComPPI
MCM2 NEB 25348397 N/A physical interaction ComPPI
OPTN NEB 23414517 24234451 25348397 physical association proximity ligation assay ComPPI,IntAct
SMURF2 NEB 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
MAPK1 NEB 25348397 N/A physical interaction ComPPI
SP1 NEB 25348397 N/A physical interaction ComPPI
PTPN11 NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SOS1 NEB 12482578 24234451 25348397 N/A circular dichroism,classical fluorescence spectroscopy,nuclear magnetic resonance ComPPI,IntAct
TPM2 NEB 25348397 N/A physical interaction ComPPI
MAPK14 NEB 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TTN NEB 12482578 16902413 24234451 25348397 physical association circular dichroism,classical fluorescence spectroscopy,two hybrid,filter binding,isothermal titration calorimetry,nuclear magnetic resonance,in vitro,in vivo ComPPI,IntAct
ACTN4 NEB 11882289 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
KLHL41 NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
HIPK1 NEB 25348397 N/A physical interaction ComPPI
APC NEB 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CAPZA1 NEB 16902413 24234451 25348397 physical association pull down ComPPI,IntAct
ABI1 NEB 14525934 15048123 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
MYOM2 NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TRIM63 NEB 18157088 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYPN NEB 11309420 12482578 14525934 24234451 25348397 N/A classical fluorescence spectroscopy,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
SNTA1 NEB 25348397 N/A physical interaction ComPPI
STRADB NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SVIL NEB 14525934 18639526 24234451 25348397 27898060 colocalization,physical association two hybrid,experimental interaction detection,pull down,fluorescence microscopy,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
STK3 NEB 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DYSF NEB 23414517 24234451 25348397 colocalization,physical association two hybrid fragment pooling approach,confocal microscopy,proximity ligation assay ComPPI,IntAct
PRKAB2 NEB 25348397 N/A physical interaction ComPPI
TRIM55 NEB 25348397 N/A physical interaction ComPPI
AKTIP NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DOCK9 NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
STYXL1 NEB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACTG2 NEB 25348397 N/A physical interaction ComPPI
TMOD1 NEB 11016930 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
ENO3 NEB 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
XIRP1 NEB 25348397 N/A physical interaction ComPPI
NEB TMOD4 25348397 N/A physical interaction ComPPI
NEB XIRP2 25348397 N/A physical interaction ComPPI
NEB KLHL40 25348397 N/A physical interaction ComPPI
NEB TPM1 25348397 N/A physical interaction ComPPI
NEB FBXL13 25348397 N/A physical interaction ComPPI
NEB ACO1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
NEB TULP3 23414517 24234451 25348397 physical association proximity ligation assay ComPPI,IntAct
S100A10 NEB 24234451 30021884 physical association cross-linking study IntAct
ACTB NEB 24234451 30021884 physical association cross-linking study IntAct
VIM NEB 24234451 30021884 physical association cross-linking study IntAct
H2BC21 NEB 24234451 30021884 physical association cross-linking study IntAct
H4C1 NEB 24234451 30021884 physical association cross-linking study IntAct
NEB WASL 21798082 27898060 stimulant N/A OmniPath
GSK3B NEB 21798082 27898060 inhibition N/A OmniPath

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