GENE：POU3F2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | POU3F2 |
| FullNmae | POU class 3 homeobox 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9215 |
| EnsembleID | ENSG00000184486 |
| Uniprot | P20265 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| POU3F2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| POU3F2 | GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0003677,GO:0003700,GO:0005515,GO:0005654,GO:0005654,GO:0005667,GO:0006357,GO:0006357,GO:0007399,GO:0008284,GO:0008544,GO:0010629,GO:0021799,GO:0021869,GO:0021897,GO:0021979,GO:0021985,GO:0022011,GO:0030182,GO:0040018,GO:0042802,GO:0045595,GO:0045944,GO:0048663,GO:0048665,GO:0048666,GO:0050770,GO:0061101,GO:0071310,GO:1990837 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA2 | POU3F2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | POU3F2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | POU3F2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SOX9 | POU3F2 | 15896776 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | POU3F2 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000044FD7 | POU3F2 | 21435193 | rna interference,inhibition | western blot,miRNA interference luciferase reporter assay | miRSponge |
| URS0000044FD7 | POU3F2 | 21435193 25416803 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
| URS0000170CF4 | POU3F2 | 20516212 25416803 | mrna cleavage,inhibition | quantitative reverse transcription pcr | TarBase |
| URS0000192A75 | POU3F2 | 22100165 22291592 23708386 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237AF9 | POU3F2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000098B3B | POU3F2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PRKACA | POU3F2 | 22135298 | phosphorylation | N/A | PhosphoSite |
| POU3F2 | SOX10 | 25361965 | interaction type | N/A | PTMCode2 |
| SOX10 | POU3F2 | 25361965 | interaction type | N/A | PTMCode2 |
| POU3F2 | PQBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| PQBP1 | POU3F2 | 25361965 | interaction type | N/A | PTMCode2 |
| SOX11 | POU3F2 | 25361965 | interaction type | N/A | PTMCode2 |
| POU3F2 | SOX11 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GTF2B | POU3F2 | 11029584 14525934 24234451 25348397 | N/A | experimental interaction detection,pull down,physical interaction | ComPPI,HPRD,IntAct |
| TBP | POU3F2 | 11029584 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| EP300 | POU3F2 | 11029584 14525934 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| PQBP1 | POU3F2 | 10332029 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD,OmniPath |
| PAX3 | POU3F2 | 11029584 24234451 25348397 | physical association | two hybrid,pull down,physical interaction | ComPPI,IntAct |
| SOX10 | POU3F2 | 11029584 14525934 24234451 25348397 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| POU3F2 | UBXN7 | 25348397 | N/A | physical interaction | ComPPI |
| SOX11 | POU3F2 | 14525934 9632656 | N/A | experimental interaction detection | HPRD |
| POU3F2 | POU3F2 | 11029584 14525934 24234451 | physical association | two hybrid,experimental interaction detection,pull down,two hybrid | HPRD,IntAct |