GENE:TWF1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TWF1 |
| FullNmae | twinfilin actin binding protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9620 |
| EnsembleID | ENSG00000151239 |
| Uniprot | Q12792 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TWF1 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TWF1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TWF1 | GO:0003779,GO:0003785,GO:0003785,GO:0005515,GO:0005524,GO:0005546,GO:0005737,GO:0005829,GO:0005884,GO:0005911,GO:0005925,GO:0010591,GO:0010613,GO:0010976,GO:0015629,GO:0030016,GO:0030016,GO:0030042,GO:0030175,GO:0030837,GO:0032587,GO:0042989,GO:0042989,GO:0043538,GO:0045296,GO:0048471,GO:0051015,GO:0051016 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | TWF1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TWF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TWF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TWF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | TWF1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00001D69F6 | TWF1 | 20571053 | rna interference,inhibition | array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS0000065D58 | TWF1 | 18668040 22473208 25416803 | mrna cleavage,inhibition | experimental interaction detection,clip | TarBase |
| URS0000338542 | TWF1 | 18668040 20584899 22815788 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,quantitative reverse transcription pcr | TarBase |
| URS00001D69F6 | TWF1 | 20571053 25416803 | mrna cleavage,inhibition | array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00000AA464 | TWF1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002FC5B0 | TWF1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032FC1A | TWF1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | TWF1 | 20371350 22815788 23592263 25416803 | mrna cleavage,inhibition | array technology,quantitative reverse transcription pcr,clip | TarBase |
| URS00000C85B2 | TWF1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | TWF1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | TWF1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001919B0 | TWF1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | TWF1 | 22815788 25416803 | mrna cleavage,inhibition | array technology,quantitative reverse transcription pcr | TarBase |
| URS00000B7E30 | TWF1 | 22815788 25416803 | mrna cleavage,inhibition | array technology,quantitative reverse transcription pcr | TarBase |
| URS00000600E6 | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000EF0B | TWF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | TWF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000157FBE | TWF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000166778 | TWF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000038718E | TWF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD02D | TWF1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D6605 | TWF1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CCBB9 | TWF1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009A9A2 | TWF1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | TWF1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | TWF1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004CD810 | TWF1 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000292B1 | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000046CDA6 | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000035CC3E | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A057E | TWF1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | TWF1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | TWF1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008F0CF | TWF1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DE669 | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | TWF1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000034B6F5 | TWF1 | 25416803 27435395 | mrna cleavage,inhibition | array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNW1 | TWF1 | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CDC5L | TWF1 | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ZBED1 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| AIMP2 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| KIF5B | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP1CB | TWF1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BTK | TWF1 | 21080425 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
| FLNA | TWF1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| DLD | TWF1 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| NTRK1 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| IQGAP1 | TWF1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BMPR2 | TWF1 | 25348397 | N/A | in vitro | ComPPI |
| MYO18A | TWF1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ABCE1 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| UNC45A | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| YAP1 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2A | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| CSE1L | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| PRPS1 | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPF | TWF1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | APP | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | TRMT1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | UBXN1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | TXNDC5 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | XPNPEP1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | USP28 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | UBA3 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | TPX2 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | FBXO25 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | IPO9 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | MCTS1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | ADSL | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | DIS3 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | USP5 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | WARS1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | DAPK1 | 24234451 25348397 25852190 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | AIMP1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | EEF1E1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | CIAPIN1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | CAPZA2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | DBN1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | PRICKLE3 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | MYH9 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | MYO1C | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | SYNPO | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | LIMA1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | ANLN | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | MYO19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TWF1 | ICAM1 | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | BCL7C | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | TIGAR | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | STYX | 25348397 | N/A | physical interaction | ComPPI |
| TWF1 | IKBKE | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| TWF1 | CCP110 | 18694559 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| TWF1 | PLEKHA7 | 24234451 25348397 28877994 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| L1TD1 | TWF1 | 24234451 25702638 | association | anti bait coimmunoprecipitation | IntAct |
| CAP2 | TWF1 | 11604420 27898060 | N/A | N/A | OmniPath |
