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GENE：LCK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LCK
FullNmae LCK proto-oncogene, Src family tyrosine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6524
EnsembleID ENSG00000182866
Uniprot P06239

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LCK pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LCK mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LCK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LCK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LCK apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LCK apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
LCK GO:0000242,GO:0001772,GO:0001784,GO:0004713,GO:0004713,GO:0004713,GO:0004713,GO:0004715,GO:0004715,GO:0004722,GO:0005102,GO:0005515,GO:0005524,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0006468,GO:0006882,GO:0006919,GO:0007169,GO:0009410,GO:0016004,GO:0018108,GO:0019901,GO:0019903,GO:0030097,GO:0030168,GO:0030217,GO:0030217,GO:0031234,GO:0031295,GO:0034116,GO:0035556,GO:0038083,GO:0038094,GO:0042169,GO:0042608,GO:0042609,GO:0042610,GO:0042802,GO:0043274,GO:0043548,GO:0045087,GO:0045121,GO:0050852,GO:0050853,GO:0050862,GO:0050870,GO:0050900,GO:0051117,GO:0051209,GO:0051249,GO:0070062,GO:1903039,GO:2001244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LCK hsa:3932 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
LCK hsa:3932 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
LCK hsa:3932 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
LCK hsa:3932 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
LCK hsa:3932 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
LCK hsa:3932 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
LCK hsa:3932 path:hsa05135 Yersinia infection - Homo sapiens (human)
LCK hsa:3932 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
LCK hsa:3932 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
LCK hsa:3932 path:hsa05340 Primary immunodeficiency - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LCK CD4 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 association N/A ACSN
LCK CD226 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
SH2D2A LCK 10975797 26192618 27896837 interaction type N/A ACSN
LAG3 LCK 15586367 22437870 26192618 27192565 7589152 interaction type N/A ACSN
BAG6 LCK 16286920 18055229 20819927 22437870 22863785 23414611 26192618 27192565 28900677 interaction type N/A ACSN
HAVCR2 LCK 16286920 18055229 20819927 22437870 22863785 23414611 26192618 27192565 28900677 interaction type N/A ACSN
CD2 LCK 19398758 19494291 26192618 26794910 interaction type N/A ACSN
CD58 LCK 19398758 19494291 26192618 26794910 interaction type N/A ACSN
B2M LCK 10358761 10559964 11154916 11509172 11717192 14508489 16181333 22076556 22790179 24457417 26192618 8642276 interaction type N/A ACSN
LCK VAV1 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK ITK 10652356 12731048 12740575 15771581 17544292 19132916 19290918 20814939 21127503 22513334 23109003 23620508 26192618 3263576 8478617 8986721 9312162 9438848 9738502 9751747 interaction type,chemical activation reaction N/A ACSN,SignaLink
LCK CD247 10652356 11062502 12731048 12740575 1505025 15536084 1706070 17544292 17979845 19290918 20814939 21127503 22513334 23109003 23620508 26192618 8478617 8986721 9438848 9738502 9751747 interaction type,chemical activation reaction N/A ACSN,SignaLink
LCK PTPRC 10652356 12414720 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 23886063 25312647 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
SPN LCK 18633355 23620508 23886063 26192618 interaction type N/A ACSN
CSK LCK 10790433 11181701 12414720 12485116 15259016 15489916 15713798 19290918 23109003 26192618 8011291 8986721 interaction type,inhibition N/A ACSN,SignaLink
LCK ZAP70 10318843 10652356 12731048 12740575 15144186 17544292 19290918 20814939 21127503 22513334 23331499 23620508 26192618 3263576 7961936 8478617 8798643 8986721 9438848 9685404 9738502 9751747 interaction type,stimulation N/A ACSN,SignaLink
LCK PRKCQ 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK CRTAM 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK SCRIB 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK FCER1G 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 26192618 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK GRB2 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 26192618 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK CLEC2B 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 26192618 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
SQSTM1 LCK 23180781 8650207 physical association gst pull down InnateDB
LCK MUC1 14766232 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
MAPK1 LCK 15967991 23180781 phosphorylation reaction protein kinase assay InnateDB
PIK3CG LCK 17998387 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZAP70 LCK 17998387 23180781 physical association anti tag coimmunoprecipitation InnateDB
SH3KBP1 LCK 15707590 23180781 physical association anti tag coimmunoprecipitation InnateDB
AXL LCK 23180781 9178760 physical association anti tag coimmunoprecipitation,far western blotting InnateDB
RUNX3 LCK 20100835 23180781 physical association anti tag coimmunoprecipitation InnateDB
FLOT1 LCK 17634952 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG LCK 20098747 23180781 physical association protein array InnateDB
LCK LCK 10318843 2250907 26467481 7642520 7961936 8798643 9685404 interaction type,phosphorylation reaction,bind,up-regulates activity,down-regulates activity N/A Signor
PTPN6 LCK 10488096 10574931 11294838 12468540 15489916 23109003 23331499 7512963 8114715 8692915 inhibition,stimulation N/A SignaLink,SignaLink
LCK NOTCH1 14583609 23331499 stimulation N/A SignaLink
LCK RASA1 11389730 1850098 23331499 stimulation N/A SignaLink
CBL LCK 11904433 23109003 inhibition N/A SignaLink
CD4 LCK 15489916 23109003 chemical activation reaction N/A SignaLink
LCK PTPN6 12459785 16231973 23109003 chemical activation reaction N/A SignaLink
LCK SIT1 10209036 23109003 chemical activation reaction N/A SignaLink
LCK PIK3R1 10488096 11526404 15032589 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
BCAR1 LCK 20005715 interaction type N/A PSP
DOK1 LCK 20005715 interaction type N/A PSP
DOK2 LCK 20005715 interaction type N/A PSP
DOK3 LCK 20005715 interaction type N/A PSP
GRAP LCK 20005715 interaction type N/A PSP,SignaLink
LAT LCK 20005715 interaction type N/A PSP,SignaLink
LAX1 LCK 20005715 interaction type N/A PSP,SignaLink
LCP2 LCK 20005715 interaction type N/A PSP
NEDD9 LCK 20005715 interaction type N/A PSP
NFKBIA LCK 20005715 interaction type N/A PSP
PAG1 LCK 20005715 interaction type N/A PSP
PIK3R1 LCK 20005715 21071413 8294442 interaction type N/A PSP,SignaLink
PXN LCK 20005715 interaction type N/A PSP,SignaLink
SH2B3 LCK 20005715 interaction type N/A PSP,SignaLink
SH2D2A LCK 10553045 18988627 20005715 interaction type N/A PSP,SignaLink
SH3BP2 LCK 20005715 interaction type N/A PSP,SignaLink
SHC1 LCK 20005715 interaction type N/A PSP
SIT1 LCK 20005715 interaction type N/A PSP
SKAP1 LCK 20005715 interaction type N/A PSP
SQSTM1 LCK 20005715 interaction type N/A PSP
TRPV4 LCK 20005715 interaction type N/A PSP
BCAR1 LCK 18988627 20005715 9020138 N/A N/A SignaLink
NEDD9 LCK 18988627 20005715 8879209 N/A N/A SignaLink
NFKBIA LCK 20005715 N/A N/A SignaLink
DOK1 LCK 20005715 20005715 N/A N/A SignaLink
DOK2 LCK 10799545 18988627 20005715 20005715 N/A N/A SignaLink
PAG1 LCK 10790433 10790433 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SQSTM1 LCK 18988627 20005715 20005715 21071413 8650207 8650207 N/A N/A SignaLink
LCP2 LCK 20005715 20005715 N/A N/A SignaLink
SHC1 LCK 20005715 20005715 N/A N/A SignaLink
DOK3 LCK 10733577 18988627 20005715 20005715 N/A N/A SignaLink
SIT1 LCK 10209036 18988627 20005715 20005715 N/A N/A SignaLink
SKAP1 LCK 18988627 20005715 20005715 21071413 9195899 9195899 N/A N/A SignaLink
TRPV4 LCK 12538589 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 LCK 18971253 20019798 7970721 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 LCK 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 LCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 LCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS2 LCK 7970721 trascriptional regulation,stimulation inferred by curator TFlink
MYB LCK 7970721 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LCK 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA LCK 22135298 phosphorylation N/A PhosphoSite
MAPK3 LCK 22135298 phosphorylation N/A PhosphoSite
LCK PRDX1 22135298 phosphorylation N/A PhosphoSite
LCK SH2D2A 22135298 phosphorylation N/A PhosphoSite
LCK CD5 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK MED28 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK PLCG2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK IL2RB 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK CD247 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK SSBP3 22135298 phosphorylation N/A PhosphoSite
LCK CHN2 22135298 phosphorylation N/A PhosphoSite
LCK ZAP70 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK CD33 22135298 phosphorylation N/A PhosphoSite
LCK CCDC50 22135298 phosphorylation N/A PhosphoSite
LCK LCK 22135298 phosphorylation N/A PhosphoSite
LCK VAV1 22135298 phosphorylation N/A PhosphoSite
LCK PTPN6 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK LCP2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK PECAM1 22135298 phosphorylation N/A PhosphoSite
LCK THEMIS 22135298 phosphorylation N/A PhosphoSite
LCK MAPK14 22135298 phosphorylation N/A PhosphoSite
LCK STAT2 22135298 phosphorylation N/A PhosphoSite
LCK STAT5A 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK SLAMF1 22135298 phosphorylation N/A PhosphoSite
LCK ADAM15 22135298 phosphorylation N/A PhosphoSite
LCK CBL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK PTEN 22135298 phosphorylation N/A PhosphoSite
LCK PRKCQ 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK ITGB2 22135298 phosphorylation N/A PhosphoSite
LCK DGKA 22135298 phosphorylation N/A PhosphoSite
LCK ACP1 22135298 phosphorylation N/A PhosphoSite
LCK ESR1 22135298 phosphorylation N/A PhosphoSite
LCK SIGLEC10 22135298 phosphorylation N/A PhosphoSite
LCK NFKBIA 22135298 phosphorylation N/A PhosphoSite
LCK SOCS3 22135298 phosphorylation N/A PhosphoSite
LCK G3BP1 22135298 phosphorylation N/A PhosphoSite
LCK PPP2CA 22135298 phosphorylation N/A PhosphoSite
LCK ITK 22135298 phosphorylation N/A PhosphoSite
LCK EZR 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK WAS 22135298 phosphorylation N/A PhosphoSite
LCK DAPP1 22135298 phosphorylation N/A PhosphoSite
LCK SLC25A4 22135298 phosphorylation N/A PhosphoSite
LCK FOXP3 22135298 phosphorylation N/A PhosphoSite
MAPK1 LCK 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CSK LCK 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCA LCK 22135298 phosphorylation N/A PhosphoSite
AXL LCK 22135298 phosphorylation N/A PhosphoSite
STAT3 LCK 25361965 interaction type N/A PTMCode2
LCK STAT3 25361965 interaction type N/A PTMCode2
PIK3CA LCK 25361965 interaction type N/A PTMCode2
LCK PIK3CA 25361965 interaction type N/A PTMCode2
LCK SKAP1 25361965 interaction type N/A PTMCode2
SKAP1 LCK 25361965 interaction type N/A PTMCode2
EZR LCK 25361965 interaction type N/A PTMCode2
STAT5A LCK 25361965 interaction type N/A PTMCode2
CD5 LCK 25361965 interaction type N/A PTMCode2
LCK SH2B3 25361965 interaction type N/A PTMCode2
SH2B3 LCK 25361965 interaction type N/A PTMCode2
PLCG2 LCK 25361965 interaction type N/A PTMCode2
LCK PTPN22 25361965 interaction type N/A PTMCode2
PTPN22 LCK 25361965 interaction type N/A PTMCode2
LCK CD3E 25361965 interaction type N/A PTMCode2
CD3E LCK 25361965 interaction type N/A PTMCode2
CD247 LCK 25361965 interaction type N/A PTMCode2
LCK LAX1 25361965 interaction type N/A PTMCode2
LAX1 LCK 25361965 interaction type N/A PTMCode2
LCK PTPRC 25361965 interaction type N/A PTMCode2
PTPRC LCK 25361965 interaction type N/A PTMCode2
LCK FASLG 25361965 interaction type N/A PTMCode2
FASLG LCK 25361965 interaction type N/A PTMCode2
LCK CD48 25361965 interaction type N/A PTMCode2
CD48 LCK 25361965 interaction type N/A PTMCode2
LCK CD2 25361965 interaction type N/A PTMCode2
CD2 LCK 25361965 interaction type N/A PTMCode2
LCK SH2D1A 25361965 interaction type N/A PTMCode2
SH2D1A LCK 25361965 interaction type N/A PTMCode2
LCK SYK 25361965 interaction type N/A PTMCode2
SYK LCK 25361965 interaction type N/A PTMCode2
LCK PTPRH 25361965 interaction type N/A PTMCode2
PTPRH LCK 25361965 interaction type N/A PTMCode2
PTPN6 LCK 25361965 interaction type N/A PTMCode2
LCK JAK3 25361965 interaction type N/A PTMCode2
JAK3 LCK 25361965 interaction type N/A PTMCode2
LCK SHC1 25361965 interaction type N/A PTMCode2
SHC1 LCK 25361965 interaction type N/A PTMCode2
LCK MAPK1 25361965 interaction type N/A PTMCode2
THY1 LCK 25361965 interaction type N/A PTMCode2
LCK THY1 25361965 interaction type N/A PTMCode2
PTK2B LCK 25361965 interaction type N/A PTMCode2
LCK PTK2B 25361965 interaction type N/A PTMCode2
CD4 LCK 25361965 interaction type N/A PTMCode2
LCK CD4 25361965 interaction type N/A PTMCode2
LCK CSK 25361965 interaction type N/A PTMCode2
CBL LCK 25361965 interaction type N/A PTMCode2
MED28 LCK 25361965 interaction type N/A PTMCode2
PRKCQ LCK 25361965 interaction type N/A PTMCode2
ZAP70 LCK 25361965 interaction type N/A PTMCode2
CD55 LCK 25361965 interaction type N/A PTMCode2
LCK CD55 25361965 interaction type N/A PTMCode2
LCP2 LCK 25361965 interaction type N/A PTMCode2
CD8A LCK 25361965 interaction type N/A PTMCode2
LCK CD8A 25361965 interaction type N/A PTMCode2
DEF6 LCK 25361965 interaction type N/A PTMCode2
LCK DEF6 25361965 interaction type N/A PTMCode2
TRAT1 LCK 25361965 interaction type N/A PTMCode2
LCK TRAT1 25361965 interaction type N/A PTMCode2
PAG1 LCK 25361965 interaction type N/A PTMCode2
LCK PAG1 25361965 interaction type N/A PTMCode2
HSP90AA1 LCK 25361965 interaction type N/A PTMCode2
LCK HSP90AA1 25361965 interaction type N/A PTMCode2
DOK2 LCK 25361965 interaction type N/A PTMCode2
LCK DOK2 25361965 interaction type N/A PTMCode2
PIK3R1 LCK 25361965 interaction type N/A PTMCode2
LCK PIK3R1 25361965 interaction type N/A PTMCode2
GAB2 LCK 25361965 interaction type N/A PTMCode2
LCK GAB2 25361965 interaction type N/A PTMCode2
CD44 LCK 25361965 interaction type N/A PTMCode2
LCK CD44 25361965 interaction type N/A PTMCode2
SIT1 LCK 25361965 interaction type N/A PTMCode2
LCK SIT1 25361965 interaction type N/A PTMCode2
KHDRBS1 LCK 25361965 interaction type N/A PTMCode2
LCK KHDRBS1 25361965 interaction type N/A PTMCode2
LIME1 LCK 25361965 interaction type N/A PTMCode2
LCK LIME1 25361965 interaction type N/A PTMCode2
CDC42 LCK 25361965 interaction type N/A PTMCode2
LCK CDC42 25361965 interaction type N/A PTMCode2
IL2RB LCK 25361965 interaction type N/A PTMCode2
CD28 LCK 25361965 interaction type N/A PTMCode2
LCK CD28 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LCP2 LCK 10556826 14525934 16354835 21725281 24234451 25348397 8702662 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,far western blotting,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS3 LCK 25348397 N/A physical interaction ComPPI
DEF6 LCK 12923183 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
WASL LCK 16293614 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
CDC42 LCK 14525934 16293614 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro ComPPI,HPRD,IntAct
SH3KBP1 LCK 25348397 N/A physical interaction ComPPI
LAT LCK 12186560 12359715 14525934 16938345 24234451 25348397 phosphorylation reaction,association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
PAK2 LCK 14525934 16374509 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LZTS2 LCK 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GRAP LCK 14525934 25348397 8995379 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
STAT1 LCK 10918587 11294897 11839738 12637327 12817007 14525934 15322115 25348397 7543024 7657660 7690989 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
WAS LCK 16107303 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
PTPRH LCK 25348397 N/A in vitro,in vivo ComPPI
ACTB LCK 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
PTPN6 LCK 10488096 10574931 11294838 12468540 14525934 19167335 24234451 25348397 7512963 8114715 8692915 dephosphorylation reaction,phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay,phosphatase assay,in vitro,in vivo ComPPI,HPRD,IntAct
HSP90AB1 LCK 22939624 24234451 25348397 physical association anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping ComPPI,IntAct
CTNND1 LCK 25348397 N/A physical interaction ComPPI
CD44 LCK 14525934 25348397 8576267 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CD4 LCK 11854499 14525934 16888650 17005671 24234451 25348397 8104794 8246987 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CBL LCK 11741956 11904433 14525934 16107303 24234451 25348397 7721825 8621719 9178909 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
VAV1 LCK 10669745 14525934 17050525 24234451 25348397 association experimental interaction detection,pull down,in vivo ComPPI,HPRD,IntAct
MAPK1 LCK 14525934 24234451 25348397 8506364 8618896 8626561 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SYK LCK 14525934 15536084 24234451 25348397 7539035 8621719 8798676 8798764 association,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
PRKCQ LCK 10652356 14525934 21964608 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTK2B LCK 14525934 25348397 9091579 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SH3BP2 LCK 14525934 15751964 24234451 25348397 association experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS1 LCK 25348397 N/A physical interaction ComPPI
CBLB LCK 25348397 N/A physical interaction ComPPI
PAG1 LCK 10790433 14525934 18070987 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
PECAM1 LCK 25348397 N/A physical interaction,in vitro ComPPI
TRPV4 LCK 12538589 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
KIT LCK 14525934 24234451 24728074 25348397 9788619 N/A experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,in vitro ComPPI,HPRD,IntAct
LYN LCK 18070987 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PIK3R1 LCK 14525934 24234451 25348397 7504174 8246987 8294442 9461588 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN11 LCK 10617656 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCA LCK 14525934 25348397 8506364 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PTPRO LCK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
FCGR3A LCK 25348397 N/A in vitro,in vivo ComPPI
CD38 LCK 10636863 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DOK1 LCK 10799545 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SH2B3 LCK 10799879 14525934 25348397 9169414 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LCK AXL 14525934 25348397 9178760 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LCK CD48 12007789 14525934 25348397 8104794 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK STAT3 10825200 14525934 18070987 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
LCK CD8A 14500983 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK CD79B 14525934 25348397 8077654 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK IFNAR1 14525934 25348397 9403695 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK CD79A 10748115 14525934 25348397 8077654 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK CSF3R 14525934 25348397 9790917 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK CSF2RB 14525934 1638019 25348397 7896837 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK CD247 14525934 16461343 24234451 25348397 8626561 9047237 phosphorylation reaction,physical association experimental interaction detection,pull down,phosphorylation reaction,physical interaction,protein kinase assay,in vivo ComPPI,HPRD,IntAct
LCK STAT5A 10825200 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK ESR2 12415108 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK GAB2 11572860 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK LIME1 14525934 14610044 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK LAX1 12359715 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK SH2D1A 14525934 15096483 24234451 24688028 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,IntAct
LCK CTLA4 14525934 25348397 9712716 9973379 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LCK EZR 12560083 1382070 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK CSK 12485116 14525934 15144186 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK CD55 1385527 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
LCK MS4A1 14525934 25348397 7545683 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK PTPN22 14525934 16461343 19167335 21719704 24234451 25348397 dephosphorylation reaction,association experimental interaction detection,pull down,physical interaction,phosphatase assay,in vivo ComPPI,HPRD,IntAct
LCK NR3C1 14525934 16888650 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct
LCK HSP90AA1 14525934 16888650 24234451 25348397 physical association anti bait coimmunoprecipitation,biophysical,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
LCK ESR1 14525934 25348397 7539106 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK FAS 14525934 25348397 8864141 N/A anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LCK FASLG 11741599 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LCK RASA1 14525934 1850098 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LCK IL2RB 10214954 14525934 2047859 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK PTPRC 10369126 19167335 24234451 25348397 7507203 8576115 dephosphorylation reaction,phosphorylation reaction,physical association affinity chromatography technology,anti bait coimmunoprecipitation,pull down,dephosphorylation reaction,physical interaction,protein kinase assay,phosphatase assay,in vitro,in vivo,protein phosphatase assay ComPPI,IntAct
LCK CD5 11298344 14525934 15144186 25348397 7513045 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro,in vivo ComPPI,HPRD
LCK CDC25C 11389730 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK RAF1 14525934 25348397 8939988 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LCK PIK3CA 14525934 25348397 8020561 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK ZAP70 10318843 10556826 14525934 15144186 16461343 24234451 25348397 7961936 8798643 9685404 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,experimental interaction detection,far western blotting,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
LCK PRKCD 11381116 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK PTPRF 12496362 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK CD28 10430626 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK ITK 14525934 15144186 25348397 9312162 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK CD2 24234451 25348397 9677430 phosphorylation reaction experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,IntAct
LCK NOTCH1 14525934 14583609 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LCK JAK3 11278738 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK PLCG2 25348397 N/A in vitro ComPPI
LCK SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 14525934 25348397 9121430 9446569 9710204 9741627 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK DLG1 14525934 24234451 25241761 25348397 9341123 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
LCK TUB 10455176 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK CCR5 11591716 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK SQSTM1 14525934 25348397 8650207 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LCK PRKACA 14525934 25348397 8506364 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK MAPK3 14525934 25348397 8506364 8618896 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK PLD2 12697812 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK KHDRBS1 11278465 14525934 16107303 16888650 24234451 25348397 7852312 9045636 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
LCK PXN 25348397 N/A physical interaction,in vivo ComPPI
LCK UNC119 14525934 14757743 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LCK TRAT1 14525934 25348397 9687533 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK SIT1 10209036 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LCK SKAP1 14525934 25348397 9195899 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK DOK2 10799545 14525934 24234451 25348397 25814554 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,validated two hybrid ComPPI,HPRD,IntAct
LCK ADAM15 11741929 14525934 16374509 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
LCK DAPP1 10880360 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK CD3E 11855827 14525934 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
LCK CTNND2 12835311 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LCK NEDD9 14525934 25348397 8879209 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK DOK3 10733577 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK KIR2DL3 14525934 25348397 9751747 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK UBE3A 25348397 N/A physical interaction ComPPI
LCK BCAR1 14525934 25348397 9020138 N/A experimental interaction detection,physical interaction ComPPI,HPRD
LCK PI4KA 25348397 N/A physical interaction ComPPI
LCK ADAM10 25348397 N/A physical interaction ComPPI
LCK THY1 1351058 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
LCK IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
LCK UHRF2 21952639 24234451 25348397 physical association physical interaction,antibody array ComPPI,IntAct
LCK CSNK2B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LCK HSP90AA2P 25348397 N/A physical interaction ComPPI
LCK FAM174A 25348397 N/A physical interaction ComPPI
LCK SOS1 25348397 N/A physical interaction ComPPI
LCK SOCS2 25348397 N/A physical interaction ComPPI
LCK CISH 25348397 N/A physical interaction ComPPI
LCK AJUBA 25348397 N/A physical interaction ComPPI
LCK G3BP1 15743820 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LCK HAVCR2 24234451 25348397 26492563 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
LCK SMAD2 25348397 N/A physical interaction ComPPI
LCK SMAD3 25348397 N/A physical interaction ComPPI
LCK BAG6 25348397 N/A physical interaction ComPPI
LCK CDKAL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCK BRCA1 25348397 N/A physical interaction ComPPI
LCK UBC 18539162 24234451 25348397 physical association nuclear magnetic resonance,pull down,physical interaction ComPPI,IntAct
LCK RIN3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LCK SMURF1 25348397 N/A physical interaction ComPPI
LCK SH2D2A 10553045 14525934 15827961 16839418 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down ComPPI,HPRD,IntAct
LCK PTPRM 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK PTPRG 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK PTPRZ1 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK PTPRB 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK PTPRJ 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK PTPN12 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
LCK BCL3 16099425 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
LCK MED25 19290556 24234451 25348397 N/A classical fluorescence spectroscopy ComPPI,IntAct
LCK ABI1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
LCK AR 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
LCK MET 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
LCK GATA3 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCK SLAMF6 24234451 24688028 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LCK GRB2 23460737 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
GAB1 LCK 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
NFKBIA LCK 12429743 14525934 25348397 8797825 9792645 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
YWHAQ LCK 25348397 N/A physical interaction ComPPI
MED28 LCK 10656681 14525934 16899217 24234451 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
ARHGAP17 LCK 11431473 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LCK MUC1 14525934 14766232 N/A experimental interaction detection HPRD
LCK LCK 14525934 15144186 17118402 24234451 24463463 8258691 8405050 8879209 8945479 phosphorylation reaction cosedimentation in solution,experimental interaction detection,fluorescence technology,x-ray crystallography,protein kinase assay HPRD,IntAct
PLCG1 LCK 14525934 1500851 N/A experimental interaction detection HPRD
LCK ACP1 14525934 9038134 N/A experimental interaction detection HPRD
LCK FLT3 24234451 28086240 N/A protein array IntAct
HSPD1 LCK 24234451 30021884 physical association cross-linking study IntAct
SOCS6 LCK 20007709 27898060 N/A N/A OmniPath
LCK SPTAN1 11971983 27898060 N/A N/A OmniPath
LCK PLCG1 1500851 27898060 7682059 stimulant N/A OmniPath
PRKACA LCK 27898060 8506364 N/A N/A OmniPath
PRKCA LCK 27898060 8506364 N/A N/A OmniPath
LCK PLCG2 11606584 12181444 15144186 15184383 16497976 19901323 27898060 7682059 stimulant N/A OmniPath
LCK TRPV4 12538589 27898060 stimulant N/A OmniPath
LCK PTEN 10866658 11948419 12077256 12297295 27898060 stimulant N/A OmniPath
LCK PRKCD 11381116 16497976 17016520 17389395 18691976 27898060 N/A N/A OmniPath
LCK SOCS3 12783885 15173187 16352613 27898060 stimulant N/A OmniPath
PTPRF LCK 12496362 27898060 stimulant N/A OmniPath
LCK PRDX1 20178744 27898060 N/A N/A OmniPath
LCK NME1 27898060 8245015 8810265 N/A N/A OmniPath
LCK CD28 10430626 22936936 27898060 8992971 stimulant N/A OmniPath
LCK LAT 12186560 12359715 14523017 16938345 27898060 stimulant N/A OmniPath
LCK ESR1 10571988 11145737 25386784 27898060 7539106 9500442 stimulant N/A OmniPath
IKBKG LCK 20098747 27898060 N/A N/A OmniPath
LCK PRKCQ 10652356 11772397 16460447 17548359 21964608 27898060 stimulant N/A OmniPath
LCK PTPN6 10488096 10574931 10617656 11294838 12468540 16497976 19167335 27898060 7512963 8114715 8692915 stimulant N/A OmniPath
PTPN6 LCK 10488096 10574931 10617656 11294838 12468540 16497976 19167335 27898060 7512963 8114715 8692915 inhibition,stimulant N/A OmniPath
LCK STAT1 10918587 11294897 11839738 12637327 12817007 15322115 27898060 7543024 7657660 7690989 stimulant N/A OmniPath
LCK MAPK3 17998336 27898060 8226850 8506364 8618896 stimulant N/A OmniPath
MAPK3 LCK 17998336 24688028 27898060 7597029 8226850 8506364 8618896 inhibition,stimulant N/A OmniPath
LCK SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 27898060 9121430 9446569 9710204 9741627 stimulant N/A OmniPath
LCK EZR 12560083 1382070 14504278 27898060 N/A N/A OmniPath
LCK NFKBIA 11231305 12429743 12909638 27898060 8797825 9792645 stimulant N/A OmniPath
LCK ITGB2 22990843 27898060 N/A N/A OmniPath
LCK PIK3R1 27898060 7504174 8246987 8294442 9115297 9461588 N/A N/A OmniPath
LCK TERT 10224060 27898060 N/A N/A OmniPath
LCK RAF1 27898060 7935389 8939988 stimulant N/A OmniPath
LCK CBL 11741956 11904433 11994282 16107303 25784557 27898060 7721825 8551236 8621719 8626543 8900205 9115297 9178909 9890970 stimulant N/A OmniPath
LCK MAPK1 15967991 27898060 8506364 8618896 8626561 stimulant N/A OmniPath
MAPK1 LCK 15967991 27898060 8226850 8262984 8506364 8618896 8626561 inhibition,stimulant N/A OmniPath
LCK MAPK8IP1 12756254 16195223 27898060 N/A N/A OmniPath
LCK NOTCH1 14583609 27898060 stimulant N/A OmniPath
LCK MUC1 14766232 27898060 stimulant N/A OmniPath
NR3C1 LCK 16888650 27898060 stimulant N/A OmniPath
LCK ZAP70 10037717 10318843 10556826 11270871 11514605 11514606 11976341 12522270 15100278 15144186 15592455 15699074 16049944 16094384 16339550 16461343 16501569 17579062 17998387 26237552 27898060 7539035 7642520 7781602 7961936 8756661 8798643 9685404 inhibition,stimulant N/A OmniPath
LCK CD247 16337488 16461343 19229850 22327568 27898060 8626561 9047237 stimulant N/A OmniPath
LCK KCNH2 10837251 11953308 27898060 N/A N/A OmniPath
LCK LCP2 10556826 11046020 12817019 16354835 21725281 22534133 22786724 27898060 8702662 stimulant N/A OmniPath
CBLB LCK 11904433 27898060 8083187 inhibition N/A OmniPath
LCK CTLA4 27898060 9712716 9973379 inhibition,stimulant N/A OmniPath
CSK LCK 12485116 15144186 1639064 16497976 18691976 19901323 27898060 inhibition,stimulant N/A OmniPath
LCK VAV2 12400014 12454019 27898060 stimulant N/A OmniPath
LCK RASA1 11389730 1850098 27898060 stimulant N/A OmniPath
LCK VAV1 10636924 10669745 15699036 16285729 17050525 20028078 24332539 27898060 898671 stimulant N/A OmniPath
LCK IL2RB 10214954 10602027 12200137 18348982 2047859 27898060 7499411 8643566 stimulant N/A OmniPath
LCK PPP1R8 27898060 9407077 N/A N/A OmniPath
SYK LCK 15536084 16497976 19664994 27898060 7539035 8621719 8798676 8798764 inhibition N/A OmniPath
LCK FOXP3 24155921 27898060 inhibition N/A OmniPath
LCK SIGLEC10 11733002 12163025 27898060 stimulant N/A OmniPath
LCK CD33 10206955 10887109 27898060 stimulant N/A OmniPath
PTCRA LCK 20626350 27898060 stimulant N/A OmniPath
LCK G3BP1 15743820 27898060 N/A N/A OmniPath
LCK DOK1 10799545 27898060 stimulant N/A OmniPath
LCK ADAM15 11741929 16374509 27898060 stimulant N/A OmniPath
LCK PIK3CG 17998387 27898060 stimulant N/A OmniPath
LCK ITK 12842872 15144186 17192257 19690332 27898060 9312162 stimulant N/A OmniPath
PTPRC LCK 10330160 10369126 11259588 11369760 12589038 15085197 19167335 2141630 2530588 27898060 7507203 8433999 8441403 8473339 8576115 8663450 9973453 inhibition,stimulant N/A OmniPath
FCGR3A LCK 15144186 18578522 27898060 8258691 8405050 8945479 stimulant N/A OmniPath
PTPRA LCK 27898060 9535845 stimulant N/A OmniPath
PTPRH LCK 12837766 27898060 inhibition N/A OmniPath
LCK SLAMF1 11806999 27898060 stimulant N/A OmniPath
LCK MED28 10656681 16899217 27898060 stimulant N/A OmniPath
LCK CHN2 19201754 27898060 N/A N/A OmniPath
LCK ACP1 10671492 10980198 16890200 17016520 27898060 9038134 N/A N/A OmniPath
LCK LIPE 15033481 15308678 16188906 2537200 27898060 3345839 9417067 N/A N/A OmniPath
LCK CETN1 11279195 27898060 N/A N/A OmniPath
LCK DEF6 12923183 18976935 27898060 stimulant N/A OmniPath
LCK CD5 11298344 11751967 15144186 27898060 7513045 stimulant N/A OmniPath
LCK DAPP1 10880360 17389395 19901323 27898060 stimulant N/A OmniPath
LCK SH2B3 10799879 27898060 9169414 stimulant N/A OmniPath
PTPN22 LCK 16461343 19167335 21719704 27898060 inhibition N/A OmniPath
LCK SSBP3 18080319 27898060 N/A N/A OmniPath
LCK CD3E 11855827 27898060 N/A N/A OmniPath
LCK SH2D2A 10553045 15827961 16839418 18541536 27898060 N/A N/A OmniPath
LCK GTF2A1L 12107178 27898060 N/A N/A OmniPath

Visualization










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