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GENE：PDIA6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDIA6
FullNmae protein disulfide isomerase family A member 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30168
EnsembleID ENSG00000143870
Uniprot Q15084

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDIA6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PDIA6 GO:0003756,GO:0005515,GO:0005615,GO:0005783,GO:0005783,GO:0005788,GO:0005788,GO:0005789,GO:0005793,GO:0005829,GO:0005886,GO:0006457,GO:0015035,GO:0015035,GO:0034663,GO:0034976,GO:0042470,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PDIA6 hsa:10130 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R PDIA6 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 PDIA6 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PDIA6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PDIA6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PDIA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
YY1 PDIA6 1330541 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009A9A2 PDIA6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000753AD PDIA6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000019F055 PDIA6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 PDIA6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 PDIA6 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A PDIA6 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000040EE1D PDIA6 20371350 22815788 23313552 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,clip TarBase
URS000015188E PDIA6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 PDIA6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PDIA6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 PDIA6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 PDIA6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED PDIA6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 PDIA6 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 PDIA6 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 PDIA6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 PDIA6 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A PDIA6 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PDIA6 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PDIA6 20371350 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 PDIA6 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 PDIA6 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
CDC73 PDIA6 25348397 N/A physical interaction ComPPI
CUL5 PDIA6 25348397 N/A physical interaction ComPPI
TPD52L2 PDIA6 25348397 N/A physical interaction ComPPI
RPN1 PDIA6 25348397 N/A physical interaction ComPPI
GLRX3 PDIA6 25348397 N/A physical interaction ComPPI
TRAF6 PDIA6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GTF2A1 PDIA6 25348397 N/A physical interaction ComPPI
CLNS1A PDIA6 25348397 N/A physical interaction ComPPI
GABARAPL2 PDIA6 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KEAP1 PDIA6 25348397 N/A physical interaction ComPPI
MCM2 PDIA6 25348397 N/A physical interaction ComPPI
MAP1LC3B PDIA6 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PTPRO PDIA6 25348397 N/A physical interaction ComPPI
CD81 PDIA6 25348397 N/A physical interaction ComPPI
CD9 PDIA6 23289620 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
JUN PDIA6 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 PDIA6 25348397 N/A physical interaction ComPPI
U2AF2 PDIA6 25348397 N/A physical interaction ComPPI
CUL3 PDIA6 25348397 N/A physical interaction ComPPI
SLC2A4 PDIA6 14525934 16396496 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SERPINH1 PDIA6 25348397 N/A physical interaction ComPPI
PDIA6 SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PDIA6 MTNR1A 14525934 17215244 24234451 25348397 26514267 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
PDIA6 MTNR1B 14525934 17215244 24234451 25348397 26514267 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
PDIA6 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA6 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA6 NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA6 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA6 HDAC5 25348397 N/A physical interaction ComPPI
PDIA6 CDK2 25348397 N/A physical interaction ComPPI
PDIA6 CUL1 25348397 N/A physical interaction ComPPI
PDIA6 CAND1 25348397 N/A physical interaction ComPPI
PDIA6 ATP13A2 22645275 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
PDIA6 FBXO6 25348397 N/A physical interaction ComPPI
PDIA6 P4HB 25348397 N/A physical interaction ComPPI
PDIA6 HSPA5 24189400 24234451 25348397 30021884 association,physical association cross-linking study,physical interaction,tandem affinity purification ComPPI,IntAct
PDIA6 TXNL1 25348397 N/A physical interaction ComPPI
PDIA6 IGBP1 25348397 N/A physical interaction ComPPI
PDIA6 TPI1 25348397 N/A physical interaction ComPPI
PDIA6 MACF1 25348397 N/A physical interaction ComPPI
PDIA6 SMURF1 25348397 N/A physical interaction ComPPI
PDIA6 CLN8 25348397 N/A physical interaction ComPPI
PDIA6 VKORC1 25348397 N/A physical interaction ComPPI
PDIA6 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 CSNK2A1 25348397 N/A physical interaction,protein kinase assay ComPPI
PDIA6 METTL23 25348397 N/A physical interaction ComPPI
PDIA6 IGSF8 25348397 N/A physical interaction ComPPI
PDIA6 ADRB2 25348397 N/A physical interaction ComPPI
PDIA6 CASP8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDIA6 PRKN 25348397 N/A physical interaction ComPPI
PDIA6 ARPC4 25348397 N/A physical interaction ComPPI
PDIA6 NRDC 25348397 N/A physical interaction ComPPI
PDIA6 C1QBP 25348397 N/A physical interaction ComPPI
PDIA6 P3H1 25348397 N/A physical interaction ComPPI
PDIA6 MAT2B 25348397 N/A physical interaction ComPPI
PDIA6 PCYT1A 25348397 N/A physical interaction ComPPI
PDIA6 PFDN5 25348397 N/A physical interaction ComPPI
PDIA6 PPP3CA 25348397 N/A physical interaction ComPPI
PDIA6 TPD52 25348397 N/A physical interaction ComPPI
PDIA6 XPO5 25348397 N/A physical interaction ComPPI
PDIA6 UGDH 25348397 N/A physical interaction ComPPI
PDIA6 HUWE1 25348397 N/A physical interaction ComPPI
PDIA6 CUL7 25348397 N/A physical interaction ComPPI
PDIA6 OBSL1 25348397 N/A physical interaction ComPPI
PDIA6 CCDC8 25348397 N/A physical interaction ComPPI
PDIA6 VWA1 25348397 N/A physical interaction ComPPI
PDIA6 PLS1 25348397 N/A physical interaction ComPPI
PDIA6 KLHL24 25348397 N/A physical interaction ComPPI
PDIA6 CCDC102A 25348397 N/A physical interaction ComPPI
PDIA6 TXNRD1 25348397 N/A physical interaction ComPPI
PDIA6 BTBD9 25348397 N/A physical interaction ComPPI
PDIA6 HNRNPLL 25348397 N/A physical interaction ComPPI
PDIA6 ISCA1 25348397 N/A physical interaction ComPPI
PDIA6 ZHX3 25348397 N/A physical interaction ComPPI
PDIA6 JMJD8 25348397 N/A physical interaction ComPPI
PDIA6 LGALS9 25348397 N/A physical interaction ComPPI
PDIA6 UNK 25348397 N/A physical interaction ComPPI
PDIA6 ACOT13 25348397 N/A physical interaction ComPPI
PDIA6 CANX 25348397 N/A physical interaction ComPPI
PDIA6 CCAR2 25348397 N/A physical interaction ComPPI
PDIA6 DNAJC3 25348397 N/A physical interaction ComPPI
PDIA6 LMAN2 25348397 N/A physical interaction ComPPI
PDIA6 MESD 25348397 N/A physical interaction ComPPI
PDIA6 NOTCH2 25348397 N/A physical interaction ComPPI
PDIA6 PRMT5 25348397 N/A physical interaction ComPPI
PDIA6 PSMD4 25348397 N/A physical interaction ComPPI
PDIA6 NTRK1 25348397 N/A physical interaction ComPPI
PDIA6 MED4 25348397 N/A physical interaction ComPPI
PDIA6 MED20 25348397 N/A physical interaction ComPPI
PDIA6 EWSR1 25348397 N/A physical interaction ComPPI
PDIA6 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDIA6 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDIA6 TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PDIA6 UBE3A 25348397 N/A physical interaction ComPPI
PDIA6 CRBN 25348397 N/A physical interaction ComPPI
PDIA6 PTPRN 25348397 N/A physical interaction ComPPI
PDIA6 DUSP13 25348397 N/A physical interaction ComPPI
PDIA6 DUSP13 25348397 N/A physical interaction ComPPI
PDIA6 MTMR14 25348397 N/A physical interaction ComPPI
PDIA6 PTPRA 25348397 N/A physical interaction ComPPI
PDIA6 CYLD 25348397 N/A physical interaction ComPPI
PDIA6 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 DNM1L 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 HSD17B10 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 PARK7 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PDIA6 CFTR 25348397 N/A physical interaction ComPPI
PDIA6 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PDIA6 MAPK13 19135240 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDIA6 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDIA6 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDIA6 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDIA6 PRDX4 21057456 24234451 25348397 colocalization,oxidoreductase activity electron transfer reaction enzymatic study ComPPI,IntAct
PDIA6 ESR1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
PDIA6 ESR2 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
PDIA6 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
PDIA6 DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
PDIA6 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
PDIA6 PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
TTC1 PDIA6 25348397 N/A physical interaction ComPPI
UBR7 PDIA6 25348397 N/A physical interaction ComPPI
METTL14 PDIA6 24234451 29507755 association anti tag coimmunoprecipitation IntAct
MC4R PDIA6 24234451 28298427 physical association ubiquitin reconstruction IntAct
PDIA6 DMXL1 24234451 30021884 physical association cross-linking study IntAct
PA2G4 PDIA6 24234451 30021884 physical association cross-linking study IntAct
PDIA6 MYCBP2 24234451 30021884 physical association cross-linking study IntAct
PDIA6 OR51F2 24234451 30021884 physical association cross-linking study IntAct
PDIA6 IGFBP5 24234451 30021884 physical association cross-linking study IntAct
PDIA6 ZNF281 24234451 30021884 physical association cross-linking study IntAct
PDIA6 SART3 24234451 30021884 physical association cross-linking study IntAct
PDIA6 ANKRD45 24234451 30021884 physical association cross-linking study IntAct
PDIA6 SLF1 24234451 30021884 physical association cross-linking study IntAct
PDIA6 ATG2B 24234451 30021884 physical association cross-linking study IntAct
PDIA6 PLEKHO1 24234451 30021884 physical association cross-linking study IntAct
PDIA6 RPL37AP8 24234451 30021884 physical association cross-linking study IntAct
PDIA6 GNMT 24234451 30021884 physical association cross-linking study IntAct
PDIA6 PRKAG2 24234451 30021884 physical association cross-linking study IntAct
PDIA6 GOLM2 24234451 30021884 physical association cross-linking study IntAct
PDIA6 DNHD1 24234451 30021884 physical association cross-linking study IntAct
PDIA6 DPEP3 24234451 30021884 physical association cross-linking study IntAct
PDIA6 RGS22 24234451 30021884 physical association cross-linking study IntAct
PDIA6 SUN2 24234451 30021884 physical association cross-linking study IntAct
PDIA6 MTRF1L 24234451 30021884 physical association cross-linking study IntAct
PDIA6 USP47 24234451 30021884 physical association cross-linking study IntAct
PDIA6 BEND3 24234451 30021884 physical association cross-linking study IntAct
L1TD1 PDIA6 24234451 25702638 association anti bait coimmunoprecipitation IntAct
PDIA6 CALR 10618487 27898060 N/A N/A OmniPath
IL7R PDIA6 20167604 27898060 N/A N/A OmniPath
CSNK2A1 PDIA6 27898060 9058200 N/A N/A OmniPath

Visualization










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