GENE：CSRP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CSRP1 |
| FullNmae | cysteine and glycine rich protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2469 |
| EnsembleID | ENSG00000159176 |
| Uniprot | P21291 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CSRP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CSRP1 | GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005925,GO:0008270,GO:0008307,GO:0030018,GO:0042805,GO:0045214,GO:0060537,GO:0070062,GO:0070527 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CSRP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | CSRP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CSRP1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CSRP1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CSRP1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | CSRP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPB | CSRP1 | 14522018 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF1A | CSRP1 | 18292576 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| REL | CSRP1 | 14522018 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT3 | CSRP1 | 18292576 8621622 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPD | CSRP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYB | CSRP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFKB1 | CSRP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RELA | CSRP1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003380CC | CSRP1 | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | CSRP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D5659 | CSRP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | CSRP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045147B | CSRP1 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000544FF1 | CSRP1 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEE35 | CSRP1 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E780 | CSRP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E2232 | CSRP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031B6ED | CSRP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | CSRP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002D2333 | CSRP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C48FA | CSRP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BAG3 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| CFL1 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| BMI1 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB2 | CSRP1 | 21706016 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TRIP4 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| ACTN1 | CSRP1 | 10926853 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CANX | CSRP1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PRKAR2A | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| ACAA2 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| EGFR | CSRP1 | 20029029 24234451 25348397 | physical association | ubiquitin reconstruction,physical interaction | ComPPI,IntAct |
| RNF2 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| YBX3 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| HSPB1 | CSRP1 | 25348397 | N/A | physical interaction | ComPPI |
| CA9 | CSRP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CSRP1 | APP | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | MACF1 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | SUZ12 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | NUP214 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | UFM1 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | FUBP3 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | TALDO1 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | ESR1 | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| CSRP1 | CNTRL | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CSRP1 | ASCC2 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | ASCC1 | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | TES | 25348397 | N/A | physical interaction | ComPPI |
| CSRP1 | REEP1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CSRP1 | BCAR1 | 24234451 25348397 28007913 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CSRP1 | CSRP1 | 14525934 7938009 | N/A | experimental interaction detection,two hybrid | HPRD |