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GENE：PTP4A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTP4A1
FullNmae protein tyrosine phosphatase 4A1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9634
EnsembleID ENSG00000112245
Uniprot Q93096

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTP4A1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTP4A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTP4A1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTP4A1 GO:0004725,GO:0004725,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005769,GO:0005783,GO:0005819,GO:0007049,GO:0008138,GO:0009898,GO:0016311,GO:0030335

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 PTP4A1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP PTP4A1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PTP4A1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PTP4A1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PTP4A1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTP4A1 18971253 9988683 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PTP4A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PTP4A1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB PTP4A1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000065D58 PTP4A1 18668040 21572407 22473208 23592263 25416803 27292025 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000003ABC4 PTP4A1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000600E6 PTP4A1 21572407 23592263 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000005481D PTP4A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PTP4A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B PTP4A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003FD55 PTP4A1 23696794 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003804D8 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F9A0F PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 PTP4A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000019907A PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002ED720 PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C48FA PTP4A1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000025EABA PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B3783 PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000042E1F PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002075FA PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039E1E1 PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006F90B PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000017DBB8 PTP4A1 21572407 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 PTP4A1 21572407 22473208 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005CF5F PTP4A1 21572407 22473208 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001DE669 PTP4A1 21572407 22473208 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000054D341 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D PTP4A1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039D790 PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BA274 PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000299AD8 PTP4A1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C PTP4A1 25416803 27377268 mrna cleavage,inhibition array technology,western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CREB3L2 PTP4A1 25361965 interaction type N/A PTMCode2
PTP4A1 CREB3L2 25361965 interaction type N/A PTMCode2
ATF7 PTP4A1 25361965 interaction type N/A PTMCode2
PTP4A1 ATF7 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RABGGTB PTP4A1 25348397 N/A physical interaction ComPPI
RPL36AL PTP4A1 25348397 N/A physical interaction ComPPI
NIFK PTP4A1 25348397 N/A physical interaction ComPPI
BLMH PTP4A1 25348397 N/A physical interaction ComPPI
NUDT12 PTP4A1 25348397 N/A physical interaction ComPPI
ZNF212 PTP4A1 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SND1 PTP4A1 25348397 N/A physical interaction ComPPI
TUBA1B PTP4A1 12235145 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
POLDIP2 PTP4A1 25348397 N/A physical interaction ComPPI
PA2G4 PTP4A1 25348397 N/A physical interaction ComPPI
PSMD1 PTP4A1 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PDHB PTP4A1 25348397 N/A physical interaction ComPPI
PTP4A2 PTP4A1 17353931 24234451 25348397 28330616 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PSMC5 PTP4A1 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
MACROD1 PTP4A1 25348397 N/A physical interaction ComPPI
PTPRE PTP4A1 25348397 N/A physical interaction ComPPI
PSMD2 PTP4A1 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
AUP1 PTP4A1 25348397 N/A physical interaction ComPPI
USP11 PTP4A1 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
SSB PTP4A1 25348397 N/A physical interaction ComPPI
ELAVL1 PTP4A1 25348397 N/A physical interaction ComPPI
PTP4A1 ATF7 25348397 N/A two hybrid,physical interaction,in vivo ComPPI
PTP4A1 TNFAIP8 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTP4A1 APP 25348397 N/A physical interaction ComPPI
PTP4A1 LAMP1 25348397 N/A physical interaction ComPPI
PTP4A1 GNL1 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PTP4A1 CREB3L2 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PTP4A1 LRRC39 25348397 N/A physical interaction ComPPI
PTP4A1 ISLR 25348397 N/A physical interaction ComPPI
PTP4A1 FNTB 25348397 N/A physical interaction ComPPI
PTP4A1 CNNM1 24234451 25348397 28330616 association,physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,proximity-dependent biotin identification ComPPI,IntAct
PTP4A1 CNNM3 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PTP4A1 CNNM4 24234451 25348397 28330616 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PTP4A1 FDFT1 25348397 N/A physical interaction ComPPI
PTP4A1 CDC25A 25348397 N/A physical interaction ComPPI
PTP4A1 RPS12 25348397 N/A physical interaction ComPPI
PTP4A1 CMSS1 25348397 N/A physical interaction ComPPI
PTP4A1 EIF3M 25348397 N/A physical interaction ComPPI
PTP4A1 MRTO4 25348397 N/A physical interaction ComPPI
PTP4A1 NUDT16 25348397 N/A physical interaction ComPPI
PTP4A1 GRSF1 25348397 N/A physical interaction ComPPI
PTP4A1 GADD45GIP1 25348397 N/A physical interaction ComPPI
PTP4A1 MRPS28 25348397 N/A physical interaction ComPPI
PTP4A1 RPL3L 25348397 N/A physical interaction ComPPI
PTP4A1 MBLAC2 25348397 N/A physical interaction ComPPI
PTP4A1 EIF3L 25348397 N/A physical interaction ComPPI
PTP4A1 PSMD3 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PTP4A1 HLCS 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PTP4A1 CNNM2 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
RPS19BP1 PTP4A1 25348397 N/A physical interaction ComPPI
ACOT8 PTP4A1 25348397 N/A physical interaction ComPPI
PTP4A1 PTP4A1 14525934 15571731 16142898 N/A experimental interaction detection HPRD
MKI67 PTP4A1 24234451 26949251 association anti tag coimmunoprecipitation IntAct
CD302 PTP4A1 25474114 27898060 N/A N/A OmniPath
PTP4A1 ATF7 11278933 27898060 inhibition N/A OmniPath

Visualization










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