Gene Information gene info

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GENE：PYGO2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PYGO2
FullNmae pygopus family PHD finger 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30257
EnsembleID ENSG00000163348
Uniprot Q9BRQ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PYGO2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PYGO2 GO:0001822,GO:0002088,GO:0003682,GO:0005515,GO:0005654,GO:0007289,GO:0007420,GO:0030879,GO:0033599,GO:0035034,GO:0042393,GO:0046872,GO:0048589,GO:0060021,GO:0060070,GO:1990907

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PYGO2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ELF1 PYGO2 18314487 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PYGO2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 PYGO2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF PYGO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PYGO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PYGO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PYGO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003CF1AD PYGO2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000054DF42 PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C4762 PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000072B4C8 PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005651EE PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002D349B PYGO2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AKT1 PYGO2 22135298 phosphorylation N/A PhosphoSite
BCL9 PYGO2 25361965 interaction type N/A PTMCode2
PYGO2 BCL9 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 PYGO2 16630820 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NF2 PYGO2 25348397 N/A physical interaction ComPPI
CREBBP PYGO2 19555349 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KMT2D PYGO2 25348397 N/A physical interaction ComPPI
ASH2L PYGO2 25348397 N/A physical interaction ComPPI
KSR2 PYGO2 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
TRIP6 PYGO2 25348397 N/A physical interaction ComPPI
RBBP5 PYGO2 25348397 N/A physical interaction ComPPI
CUL4A PYGO2 25348397 N/A physical interaction ComPPI
TRRAP PYGO2 25348397 N/A physical interaction ComPPI
SUPT3H PYGO2 25348397 N/A physical interaction ComPPI
KAT2A PYGO2 25348397 N/A physical interaction ComPPI
CTNNB1 PYGO2 25348397 N/A physical interaction ComPPI
DDB1 PYGO2 25348397 N/A physical interaction ComPPI
AKT1 PYGO2 25348397 N/A physical interaction ComPPI
BCL9 PYGO2 11955446 14525934 14612447 17113272 21399610 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PYGO2 KLC2 25348397 N/A physical interaction ComPPI
PYGO2 MOV10 25348397 N/A physical interaction ComPPI
PYGO2 NXF1 25348397 N/A physical interaction ComPPI
PYGO2 DCAF1 25348397 N/A physical interaction ComPPI
PYGO2 JRK 21399610 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
WDR5 PYGO2 25348397 N/A physical interaction ComPPI
AKT1 PYGO2 26170450 27898060 N/A N/A OmniPath

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