GENE：CTNND2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CTNND2 |
| FullNmae | catenin delta 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2516 |
| EnsembleID | ENSG00000169862 |
| Uniprot | Q9UQB3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CTNND2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CTNND2 | GO:0005515,GO:0005634,GO:0005737,GO:0005886,GO:0005912,GO:0007043,GO:0007155,GO:0007165,GO:0008013,GO:0014069,GO:0016055,GO:0030425,GO:0043204,GO:0045296,GO:0050808,GO:0060828,GO:0060997,GO:0060997,GO:0098609 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CTNND2 | hsa:1501 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CTNND2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | CTNND2 | 18414489 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,chromatin immunoprecipitation assay | TFlink |
| GATA3 | CTNND2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CTNND2 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CTNND2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CTNND2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | CTNND2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PDZD2 | CTNND2 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND2 | PDZD2 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND2 | SPHK1 | 25361965 | interaction type | N/A | PTMCode2 |
| SPHK1 | CTNND2 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND2 | ATN1 | 25361965 | interaction type | N/A | PTMCode2 |
| ATN1 | CTNND2 | 25361965 | interaction type | N/A | PTMCode2 |
| LRRC7 | CTNND2 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND2 | LRRC7 | 25361965 | interaction type | N/A | PTMCode2 |
| CDH1 | CTNND2 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND2 | CDH1 | 25361965 | interaction type | N/A | PTMCode2 |
| CDH2 | CTNND2 | 25361965 | interaction type | N/A | PTMCode2 |
| CTNND2 | CDH2 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NUDT21 | CTNND2 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TTR | CTNND2 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| MCM2 | CTNND2 | 25348397 | N/A | physical interaction | ComPPI |
| ERBIN | CTNND2 | 24234451 24550280 25348397 | physical association | phage display,in vitro,in vivo | ComPPI,IntAct |
| LCK | CTNND2 | 12835311 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CDH1 | CTNND2 | 25348397 | N/A | in vivo | ComPPI |
| CLK1 | CTNND2 | 25348397 | N/A | physical interaction | ComPPI |
| DLG1 | CTNND2 | 24234451 24550280 25348397 30126976 | physical association | phage display,p8 filamentous phage display | ComPPI,IntAct |
| PSEN2 | CTNND2 | 10037471 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CTTN | CTNND2 | 12835311 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| LRRC7 | CTNND2 | 11729199 14525934 24234451 24550280 25348397 | physical association | two hybrid,experimental interaction detection,phage display,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| CTNND2 | PDZD2 | 10896674 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| CTNND2 | CTNNB1 | 14525934 25348397 9971746 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CTNND2 | CDH2 | 14525934 25348397 9971746 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CTNND2 | MAGI2 | 10080919 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CTNND2 | SPHK1 | 14525934 15193146 25348397 | N/A | two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD |
| CTNND2 | FYN | 12835311 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CTNND2 | PSEN1 | 10037471 10208590 14525934 25348397 9223106 | N/A | two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| CTNND2 | ATN1 | 25348397 | N/A | physical interaction | ComPPI |
| CTNND2 | ZBTB33 | 25348397 | N/A | physical interaction | ComPPI |
| CTNND2 | LNX1 | 25348397 | N/A | physical interaction | ComPPI |
| CTNND2 | SCRIB | 24234451 24550280 25348397 30126976 | physical association | phage display,p8 filamentous phage display | ComPPI,IntAct |
| CTNND2 | ABL1 | 11891774 14525934 | N/A | experimental interaction detection | HPRD |
| CTNND2 | CTNND2 | 10037471 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
| CTNND2 | PTGER4 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| CTNND2 | DLG4 | 24234451 30126976 | N/A | p8 filamentous phage display | IntAct |
| CTNND2 | CDH1 | 14610055 27898060 9971746 | stimulant | N/A | OmniPath |
| AKT1 | CTNND2 | 17993462 27898060 | N/A | N/A | OmniPath |
| CTNND2 | CDH2 | 14610055 27898060 9971746 | stimulant | N/A | OmniPath |
| ERBIN | CTNND2 | 11821434 27898060 | N/A | N/A | OmniPath |
| CTNND2 | ERBIN | 11821434 27898060 | stimulant | N/A | OmniPath |
| CTNND2 | CDH5 | 14610055 27898060 | stimulant | N/A | OmniPath |
| MAGI2 | CTNND2 | 10080919 27898060 | N/A | N/A | OmniPath |
| CTNND2 | CDH3 | 14610055 27898060 | stimulant | N/A | OmniPath |