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GENE：DCK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DCK
FullNmae deoxycytidine kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2704
EnsembleID ENSG00000156136
Uniprot P27707

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DCK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DCK GO:0004136,GO:0004137,GO:0004137,GO:0004138,GO:0005524,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006220,GO:0009224,GO:0016310,GO:0042803,GO:0043771,GO:0106383,GO:1901293

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DCK hsa:1633 path:hsa00230 Purine metabolism - Homo sapiens (human)
DCK hsa:1633 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
DCK hsa:1633 path:hsa01100 Metabolic pathways - Homo sapiens (human)
DCK hsa:1633 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 DCK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC DCK 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SP1 DCK 14514691 20544528 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
SP3 DCK 14514691 trascriptional regulation,stimulation chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
USF1 DCK 14514691 trascriptional regulation,stimulation chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
USF2 DCK 14514691 trascriptional regulation,stimulation chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
FOXP3 DCK 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DCK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 DCK 20544528 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 DCK 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000012930C DCK 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D DCK 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 DCK 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK1D DCK 22135298 phosphorylation N/A PhosphoSite
ATR DCK 22135298 phosphorylation N/A PhosphoSite
ATM DCK 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RXRG DCK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CHRAC1 DCK 25348397 N/A physical interaction ComPPI
NTRK1 DCK 25348397 N/A physical interaction ComPPI
RANBP1 DCK 25348397 N/A physical interaction ComPPI
TFEC DCK 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HSPE1 DCK 25348397 N/A physical interaction ComPPI
ELAVL1 DCK 25348397 N/A physical interaction ComPPI
THOP1 DCK 25348397 N/A physical interaction ComPPI
TALDO1 DCK 25348397 N/A physical interaction ComPPI
DDX19B DCK 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CHMP4A DCK 25348397 N/A physical interaction ComPPI
MED19 DCK 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ADSS2 DCK 25348397 N/A physical interaction ComPPI
GOLM1 DCK 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IDH1 DCK 25348397 N/A physical interaction ComPPI
DCK CBX3 25348397 N/A physical interaction ComPPI
DCK EFHD2 25348397 N/A physical interaction ComPPI
DCK PTMS 25348397 N/A physical interaction ComPPI
DCK RBBP7 25348397 N/A physical interaction ComPPI
DGUOK DCK 25348397 N/A physical interaction ComPPI
TYMS DCK 25348397 N/A physical interaction ComPPI
DCK DCK 21900206 24234451 physical association two hybrid IntAct
CSNK1D DCK 16361699 17065079 17350163 18258203 20544527 20637175 21351740 22490700 24462681 25101980 27898060 N/A N/A OmniPath

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