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GENE：DRG1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DRG1
FullNmae developmentally regulated GTP binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3029
EnsembleID ENSG00000185721
Uniprot Q9Y295

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DRG1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DRG1 GO:0002181,GO:0003924,GO:0005515,GO:0005525,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005844,GO:0008017,GO:0016020,GO:0016604,GO:0030955,GO:0031116,GO:0042802,GO:1901673

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DRG1 RWDD1 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DRG1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DRG1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 DRG1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DRG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DRG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DRG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DRG1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC DRG1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 DRG1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 DRG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075ABF4 DRG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 DRG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002971AB DRG1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000081D1E DRG1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D1FC DRG1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001310DE DRG1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075B0F6 DRG1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STK16 DRG1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
UBE2I DRG1 25348397 N/A physical interaction ComPPI
SNW1 DRG1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L DRG1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
STK16 DRG1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3GLB1 DRG1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 SKIL 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DRG1 COIL 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DRG1 PHC2 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DRG1 TAL1 14525934 24234451 25348397 9824680 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
DRG1 RWDD1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
DRG1 CAPNS1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
DRG1 LYL1 14525934 25348397 27898060 8649774 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
DRG1 HDGF 25348397 N/A physical interaction ComPPI
DRG1 ZC3H15 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DRG1 GRB2 25348397 N/A physical interaction ComPPI
DRG1 BARD1 25348397 N/A physical interaction ComPPI
DRG1 BRCA1 25348397 N/A physical interaction ComPPI
DRG1 PAXIP1 25348397 N/A physical interaction ComPPI
DRG1 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DRG1 FN1 25348397 N/A physical interaction ComPPI
DRG1 ITGA4 25348397 N/A physical interaction ComPPI
DRG1 CLDN1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DRG1 SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
DRG1 HECW2 25348397 N/A physical interaction ComPPI
DRG1 WWOX 25348397 N/A physical interaction ComPPI
DRG1 PHKG2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DRG1 STAU1 25348397 N/A physical interaction ComPPI
DRG1 SSX2IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DRG1 CUL7 25348397 N/A physical interaction ComPPI
DRG1 CCDC8 25348397 N/A physical interaction ComPPI
DRG1 ABL1 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DRG1 MAST3 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DRG1 LRRC41 25348397 N/A physical interaction ComPPI
DRG1 NTMT1 25348397 N/A physical interaction ComPPI
DRG1 HAO1 25348397 N/A physical interaction ComPPI
DRG1 CAND1 25348397 N/A physical interaction ComPPI
DRG1 CAND2 25348397 N/A physical interaction ComPPI
DRG1 FEN1 25348397 N/A physical interaction ComPPI
DRG1 IFRD2 25348397 N/A physical interaction ComPPI
DRG1 KIF23 25348397 N/A physical interaction ComPPI
DRG1 NAA15 25348397 N/A physical interaction ComPPI
DRG1 SFN 25348397 N/A physical interaction ComPPI
DRG1 NTRK1 25348397 N/A physical interaction ComPPI
DRG1 XPO1 25348397 N/A physical interaction ComPPI
DRG1 RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DRG1 OSCP1 25348397 N/A physical interaction ComPPI
DRG1 COPZ1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 SUB1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 CHORDC1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 DIS3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 ZC3HAV1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 SEPTIN7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 PRCC 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 CDK5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 CYLD 25348397 N/A physical interaction ComPPI
DRG1 MTF1 25348397 N/A physical interaction ComPPI
DRG1 BRD1 25348397 N/A physical interaction ComPPI
DRG1 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DRG1 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DRG1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DRG1 STK4 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DRG1 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DRG1 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DRG1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
DRG1 LARP7 18281698 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SARNP DRG1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DRG1 DRG1 23711155 24234451 N/A molecular sieving IntAct
TRADD DRG1 24234451 30561431 association virotrap IntAct
STK16 DRG1 18184589 25416956 27898060 N/A N/A OmniPath

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